RetrogeneDB ID:

retro_pabe_794

Retrocopy
location
Organism:Orangutan (Pongo abelii)
Coordinates:11:104029167..104030381(-)
Located in intron of:ENSPPYG00000003833
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:DKFZP459C0539
Ensembl ID:ENSPPYG00000008456
Aliases:None
Description:DKFZP459C0539 protein [Source:RefSeq peptide;Acc:NP_001128829]


Retrocopy-Parental alignment summary:






>retro_pabe_794
GAAAGACCATCTTATGCCCCACCTCCCACCCCAGCTCCTACAACACAAATGCCCAGCACACCAAGGTTTGTGGGATACAG
TCCATACAGTCATCTCGCCTACAACAATTACAGGCTGGGAGGGAACCCTGGTACCAACAGCCAGTTCACGGCATCCTCTG
GTGCTACGATTCCAAAACCCCCAAAGCCACCAGATAAGCTGCTGATGCCCTACATGAGGTACAGCTGAAAGGTCTGGGAC
CAAAGTAAGGGCTTCCAACCCAGACCTAAAGTTGTGGAAGACTGGCAAGATTATTGGTGGCATGTGGCGAGATCTCACTG
ATGAAGAAAAACAAGAATATTTAAATGGATACGAAGCAGAAAGTTAGAGTACAATGAATTTATGAAGGCCTATCATAATT
CCCCCACCTACCTTGCTTACGTAAATGCAAAAAATCGTGCAGAAGCTGCTTTAGAGGAAGAAAGTTGACAGAGACAGTCT
CACATGGAGAAAGGAGAACTATATATGAGCATTCAGCTCTGCTGAAGATCCAGATGATTATGATGATGGGTTTTTAGTGA
AGCATACAGCCACTGACTGTTTCCAGAGAAACCGTCACCTCTTCAGTGAAATCCTTAGTGAGAGTGTGGTGCCAGACGTT
CGGTCAGTTGTCGCAACAGCTAGAATGCAGGTCCTTAAATGACAGGTTCAGTCCTTAATGGTTCCTCAGCGAAAACTAGA
AGCTGAACTTCTTCAAATACAGGAGGAGAAGAGGAAATTCCTAGAAAGCACAGATTCACTTAACAATGAACTTAAAAGGT
TGTGCGGTCTGACAGTAGAAGTGGATATGGAGAGAGTTGCAGCTGAGATTGCACAGGCAGAGGAACAGACTGGCAAAAAG
CAGGAGGAAAGGGAGAAGGAGGCAGCAGAGCAAGCCGAGTGCAGTCAAAGCAGCATCATTCGTGAGGAAGAACAAGCACC
AAACAAAGGTGAGGAGAAGAAAGACGAGGAGAACATTCCAATGGAGACAGAGGAGACACACCTTGAAGAAACCACAGAGT
CAACAGAATGGTGAAGAAGGCACGTCTACTACTGAGGACAAGGAGAGTGGGCAGGAGGGGGTTGACAGTATGGCAGAGGA
AGGAACCAGTGATAGTAACACTGGCTCAGAGAGCAACAGCACAACAGTGGAAGAGCCACTGACAGATCCCCTACCAGAAG
ATGAGAAAAAAGAA

ORF - retro_pabe_794 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 84.5 %
Parental protein coverage: 99.51 %
Number of stop codons detected: 3
Number of frameshifts detected 4


Retrocopy - Parental Gene Alignment:

ParentalKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMP
.RPSYAPPPTPAP.TQMPSTP.FVGY.PYSHLAYNNYRLGGNPGTNS..TASSG.TIPKPPKPPDK.LMP
RetrocopyERPSYAPPPTPAPTTQMPSTPRFVGYSPYSHLAYNNYRLGGNPGTNSQFTASSGATIPKPPKPPDKLLMP
ParentalYMRYSRKVWDQ-VKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAE-KIEYNESMKAYHNSPAYL
YMRYS.KVWDQ.V.ASNPDLKLW..GKIIGGMWRDLTDEEKQEYLN.YEAE.K.EYNE.MKAYHNSP.YL
RetrocopyYMRYS*KVWDQ>VRASNPDLKLWKTGKIIGGMWRDLTDEEKQEYLNGYEAE<KLEYNEFMKAYHNSPTYL
ParentalAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQ-PAEDPDDYDDGFSMKHTATARFQRNHRLISEILSE
AY.NAK.RAEAALEEES.QRQS.MEKGE.YMSIQ..AEDPDDYDDGF..KHTAT..FQRN..L.SEILSE
RetrocopyAYVNAKNRAEAALEEES*QRQSHMEKGELYMSIQ>SAEDPDDYDDGFLVKHTATDCFQRNRHLFSEILSE
ParentalSVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVE
SVVPDVRSVV.TARMQVLK.QVQSLMV.QRKLEAELLQI....QE.KRKFLESTDS.NNELKRLCGL.VE
RetrocopySVVPDVRSVVATARMQVLK*QVQSLMVPQRKLEAELLQI----QEEKRKFLESTDSLNNELKRLCGLTVE
ParentalVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEE
VDME..AAEIAQAEEQ..K.QEEREKEAAEQAE.SQSSI..EEEQA.NKGEEKKD.ENIPMETEETHLEE
RetrocopyVDMERVAAEIAQAEEQTGKKQEEREKEAAEQAECSQSSIIREEEQAPNKGEEKKDEENIPMETEETHLEE
ParentalTTES-QQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE
TTES.Q...E....T.EDKESGQEGVDSMAEEGTSDSNTGSESNS.TVEEP.TDP.PEDEKKE
RetrocopyTTES>QNGEEGTSTT-EDKESGQEGVDSMAEEGTSDSNTGSESNSTTVEEPLTDPLPEDEKKE

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .11 RPM 50 .65 RPM
SRP007412_cerebellum 0 .00 RPM 64 .81 RPM
SRP007412_heart 0 .03 RPM 22 .85 RPM
SRP007412_kidney 0 .10 RPM 52 .07 RPM
SRP007412_liver 0 .03 RPM 29 .32 RPM
Pongo abelii was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_pabe_794 retrocopy.
Pongo abelii was not studied using FANTOM5 data.
retro_pabe_794 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_pabe_794 has 2 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Homo sapiens retro_hsap_922
Pan troglodytes retro_ptro_639

Parental genes homology:
Parental genes homology involve 21 parental genes, and 82 retrocopies.

Species Parental gene accession Retrocopies number
Canis familiaris ENSCAFG000000160258 retrocopies
Choloepus hoffmanni ENSCHOG000000087273 retrocopies
Callithrix jacchus ENSCJAG000000135734 retrocopies
Felis catus ENSFCAG000000096462 retrocopies
Homo sapiens ENSG000000735845 retrocopies
Gorilla gorilla ENSGGOG000000118032 retrocopies
Microcebus murinus ENSMICG000000098214 retrocopies
Myotis lucifugus ENSMLUG000000046091 retrocopy
Macaca mulatta ENSMMUG000000040053 retrocopies
Mustela putorius furoENSMPUG000000146604 retrocopies
Mus musculus ENSMUSG000000379355 retrocopies
Nomascus leucogenys ENSNLEG000000019574 retrocopies
Oryctolagus cuniculus ENSOCUG000000089811 retrocopy
Otolemur garnettii ENSOGAG000000016527 retrocopies
Ochotona princeps ENSOPRG000000009851 retrocopy
Pongo abelii ENSPPYG00000008456 4 retrocopies
Pan troglodytes ENSPTRG000000229025 retrocopies
Pteropus vampyrus ENSPVAG000000113551 retrocopy
Rattus norvegicus ENSRNOG000000106767 retrocopies
Tupaia belangeri ENSTBEG0000000077010 retrocopies
Tursiops truncatus ENSTTRG000000138851 retrocopy



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