RetrogeneDB ID: retro_ptro_2756

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 8:62369984..62370224(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NDUFA4
• Ensembl ID: ENSPTRG00000018934
• Aliases: None
• Description: Pan troglodytes NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa (NDUFA4), nuclear gene encoding mitochondrial protein, mRNA. [Source:RefSeq mRNA;Acc:NM_001079924]

Sequence

>retro_ptro_2756
ATGCTCTGCTAGATTCTCAGTCAGGCCAAGAAGCATCTGAGCTTGATCCCCCGCTTTGTATTTATTGGAGCTGGAGGTAC
TGGAGCAGCACAATTTGTCTTGCATCTGGCATCGTTCAATCCAGATGTTAGCTGGGACAGAAAGAACCCAGAGCCCTGGA
ACAAATGGGGTCCCAATGATCAATACAAATTTTACTCAATGAATGTAGATTACAGCAAACTGAAGAAAGAAGGTCCAGAT

Alignment

ORF - retro_ptro_2756 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.25 %
• Parental protein coverage: 98.77 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPNDQYKFYSVNVD
          ML..I..QAKKH.SLIP.FVFIG.G.TGA....L.LA.FNPDV.WDR.NPEPWNK.GPNDQYKFYS.NVD
Retrocopy MLC*ILSQAKKHLSLIPRFVFIGAGGTGAAQFVLHLASFNPDVSWDRKNPEPWNKWGPNDQYKFYSMNVD

Parental  YSKLKKERPD
          YSKLKKE.PD
Retrocopy YSKLKKEGPD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	238.82 RPM
SRP007412_cerebellum	0.00 RPM	80.80 RPM
SRP007412_heart	0.00 RPM	209.21 RPM
SRP007412_kidney	0.00 RPM	128.12 RPM
SRP007412_liver	0.00 RPM	39.74 RPM
SRP007412_testis	0.00 RPM	7.48 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_2756 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_2756 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_2756 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4067
Pongo abelii	retro_pabe_3339

---

Parental genes homology:

Parental genes homology involve 16 parental genes, and 135 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000002493	10 retrocopies	retro_amel_1356, retro_amel_1633, retro_amel_18, retro_amel_1800, retro_amel_1866, retro_amel_533, retro_amel_608, retro_amel_638, retro_amel_845, retro_amel_955,
Choloepus hoffmanni	ENSCHOG00000012330	1 retrocopy	retro_chof_2667,
Callithrix jacchus	ENSCJAG00000000748	3 retrocopies	retro_cjac_3291, retro_cjac_36, retro_cjac_90,
Dasypus novemcinctus	ENSDNOG00000011217	12 retrocopies	retro_dnov_1874, retro_dnov_1921, retro_dnov_2015, retro_dnov_2258, retro_dnov_2566, retro_dnov_2567, retro_dnov_2641, retro_dnov_349, retro_dnov_506, retro_dnov_725, retro_dnov_744, retro_dnov_764,
Homo sapiens	ENSG00000189043	18 retrocopies	retro_hsap_1459, retro_hsap_200, retro_hsap_2374, retro_hsap_2386, retro_hsap_259, retro_hsap_2685, retro_hsap_2726, retro_hsap_285, retro_hsap_3241, retro_hsap_4067, retro_hsap_4188, retro_hsap_4292, retro_hsap_4699, retro_hsap_4700, retro_hsap_4750, retro_hsap_4856, retro_hsap_650, retro_hsap_877,
Gorilla gorilla	ENSGGOG00000001437	3 retrocopies	retro_ggor_249, retro_ggor_30, retro_ggor_567,
Microcebus murinus	ENSMICG00000013999	5 retrocopies	retro_mmur_1225, retro_mmur_1314, retro_mmur_133, retro_mmur_341, retro_mmur_696,
Myotis lucifugus	ENSMLUG00000006470	6 retrocopies	retro_mluc_1778, retro_mluc_1821, retro_mluc_329, retro_mluc_450, retro_mluc_517, retro_mluc_849,
Macaca mulatta	ENSMMUG00000020894	2 retrocopies	retro_mmul_272, retro_mmul_274,
Monodelphis domestica	ENSMODG00000014107	2 retrocopies	retro_mdom_1095, retro_mdom_1593,
Oryctolagus cuniculus	ENSOCUG00000029372	1 retrocopy	retro_ocun_41,
Otolemur garnettii	ENSOGAG00000000358	17 retrocopies	retro_ogar_1023, retro_ogar_1026, retro_ogar_1319, retro_ogar_1403, retro_ogar_1566, retro_ogar_1960, retro_ogar_1976, retro_ogar_2050, retro_ogar_2350, retro_ogar_2528, retro_ogar_3023, retro_ogar_3413, retro_ogar_3434, retro_ogar_3457, retro_ogar_694, retro_ogar_731, retro_ogar_997,
Pongo abelii	ENSPPYG00000017780	5 retrocopies	retro_pabe_2296, retro_pabe_24, retro_pabe_301, retro_pabe_3339, retro_pabe_678,
Pan troglodytes	ENSPTRG00000018934	19 retrocopies	retro_ptro_1134, retro_ptro_1736, retro_ptro_1745, retro_ptro_1811, retro_ptro_182, retro_ptro_1842, retro_ptro_219, retro_ptro_2191, retro_ptro_235, retro_ptro_2756 , retro_ptro_2844, retro_ptro_2908, retro_ptro_3034, retro_ptro_3123, retro_ptro_3165, retro_ptro_3233, retro_ptro_473, retro_ptro_766, retro_ptro_993,
Tupaia belangeri	ENSTBEG00000016629	16 retrocopies	retro_tbel_1049, retro_tbel_1848, retro_tbel_2008, retro_tbel_2058, retro_tbel_2194, retro_tbel_2274, retro_tbel_2423, retro_tbel_2761, retro_tbel_3262, retro_tbel_4255, retro_tbel_4309, retro_tbel_436, retro_tbel_4380, retro_tbel_4426, retro_tbel_4719, retro_tbel_815,
Tarsius syrichta	ENSTSYG00000000041	15 retrocopies	retro_tsyr_1427, retro_tsyr_1650, retro_tsyr_1766, retro_tsyr_1948, retro_tsyr_1973, retro_tsyr_1974, retro_tsyr_198, retro_tsyr_270, retro_tsyr_425, retro_tsyr_473, retro_tsyr_492, retro_tsyr_659, retro_tsyr_685, retro_tsyr_821, retro_tsyr_937,