RetrogeneDB ID: retro_mdom_610

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 1:523608364..523608837(-)
• Located in intron of: ENSMODG00000015208

Retrocopy information

• Ensembl ID: ENSMODG00000015211
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSMODG00000004242
• Aliases: None
• Description: None

Sequence

>retro_mdom_610
ATGGCCGCCTACAAGCTCGTGCTAATCCGCCACGGAGAGAGCGCCTGGAACCTGGAGACCGCTTCAGCGGTTGGTACGAC
GCAGACCTGAGCCCCGCCGGGCACCAAGAGGCCCAGCGTGGCGGCCAAGCTCTGCGAGATGCTGGCTATGAATTTGATAT
CTGCTTCACCTCTGTCCAAAAGAAAGCAATTTGTACTCTTTGGATAGTACTAGATGCTATTGACCAAATGTGGCTGCCTG
TTGTGAGGACCTGGCGCCTCAATGAGAGGCATTATGGAGGTCTGACGGGCCTCAACAAAGCAGAGACAGCTGCTAAGCAT
GGTGAGGCCCAGGTCAAGATCTGGCAACGATCCTACGATATCCCACCACCTCCGATGGAGGCCAACCACCCCTTCTACAG
CAACATCAACAAGGACCGGCGCCATGCAGATCTTACTGAGGATCAGTTGCCCTCCTGTGAGAGCCTGAAAGAC

Alignment

ORF - retro_mdom_610 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.23 %
• Parental protein coverage: 50.97 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MAAYKLVLIRHGESAWNLE-NRFSGWYDADLSPAGHQEAQRGGQALRDAGYEFDICFTSVQKRAIRTLWI
          MAAYKLVLIRHGESAWNLE..RFSGWYDADLSPAGHQEAQRGGQALRDAGYEFDICFTSVQK.AI.TLWI
Retrocopy MAAYKLVLIRHGESAWNLE<DRFSGWYDADLSPAGHQEAQRGGQALRDAGYEFDICFTSVQKKAICTLWI

Parental  VLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDIPPPPMEANHPFYSNINKD
          VLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIW.RSYDIPPPPMEANHPFYSNINKD
Retrocopy VLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWQRSYDIPPPPMEANHPFYSNINKD

Parental  RRYADLTEDQLPSCESLKD
          RR.ADLTEDQLPSCESLKD
Retrocopy RRHADLTEDQLPSCESLKD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.36 RPM	1356.70 RPM
SRP007412_cerebellum	0.33 RPM	1427.26 RPM
SRP007412_heart	0.40 RPM	839.67 RPM
SRP007412_kidney	0.00 RPM	707.14 RPM
SRP007412_liver	0.00 RPM	1078.47 RPM
SRP007412_testis	0.00 RPM	315.47 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_610 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_610 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 107 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000012697	2 retrocopies	retro_btau_1611, retro_btau_472,
Canis familiaris	ENSCAFG00000009062	1 retrocopy	retro_cfam_1297,
Callithrix jacchus	ENSCJAG00000016575	1 retrocopy	retro_cjac_370,
Cavia porcellus	ENSCPOG00000006844	4 retrocopies	retro_cpor_158, retro_cpor_539, retro_cpor_605, retro_cpor_660,
Erinaceus europaeus	ENSEEUG00000005630	1 retrocopy	retro_eeur_680,
Echinops telfairi	ENSETEG00000002467	1 retrocopy	retro_etel_1595,
Homo sapiens	ENSG00000171314	12 retrocopies	retro_hsap_1048, retro_hsap_1052, retro_hsap_1142, retro_hsap_2235, retro_hsap_2604, retro_hsap_3083, retro_hsap_3488, retro_hsap_4249, retro_hsap_4686, retro_hsap_4821, retro_hsap_885, retro_hsap_913,
Gorilla gorilla	ENSGGOG00000028602	13 retrocopies	retro_ggor_1220, retro_ggor_1500, retro_ggor_1667, retro_ggor_1824, retro_ggor_2061, retro_ggor_2118, retro_ggor_2353, retro_ggor_2849, retro_ggor_3005, retro_ggor_3034, retro_ggor_716, retro_ggor_738, retro_ggor_827,
Loxodonta africana	ENSLAFG00000015979	1 retrocopy	retro_lafr_886,
Microcebus murinus	ENSMICG00000007657	1 retrocopy	retro_mmur_135,
Myotis lucifugus	ENSMLUG00000009117	6 retrocopies	retro_mluc_1280, retro_mluc_1595, retro_mluc_1741, retro_mluc_2246, retro_mluc_632, retro_mluc_745,
Macaca mulatta	ENSMMUG00000020027	1 retrocopy	retro_mmul_119,
Monodelphis domestica	ENSMODG00000004242	4 retrocopies	retro_mdom_1342, retro_mdom_1893, retro_mdom_610 , retro_mdom_668,
Mustela putorius furo	ENSMPUG00000017045	1 retrocopy	retro_mputfur_1409,
Mus musculus	ENSMUSG00000011752	6 retrocopies	retro_mmus_1741, retro_mmus_2221, retro_mmus_3012, retro_mmus_411, retro_mmus_729, retro_mmus_769,
Nomascus leucogenys	ENSNLEG00000013804	10 retrocopies	retro_nleu_1367, retro_nleu_1535, retro_nleu_1658, retro_nleu_2012, retro_nleu_2139, retro_nleu_2196, retro_nleu_2205, retro_nleu_2488, retro_nleu_2667, retro_nleu_280,
Oryctolagus cuniculus	ENSOCUG00000005679	5 retrocopies	retro_ocun_1016, retro_ocun_1081, retro_ocun_350, retro_ocun_706, retro_ocun_976,
Pongo abelii	ENSPPYG00000002530	9 retrocopies	retro_pabe_1325, retro_pabe_2309, retro_pabe_2554, retro_pabe_2639, retro_pabe_2881, retro_pabe_3389, retro_pabe_3639, retro_pabe_3749, retro_pabe_671,
Pan troglodytes	ENSPTRG00000002807	12 retrocopies	retro_ptro_1082, retro_ptro_1580, retro_ptro_1645, retro_ptro_1755, retro_ptro_2080, retro_ptro_2361, retro_ptro_2889, retro_ptro_2890, retro_ptro_3114, retro_ptro_3238, retro_ptro_634, retro_ptro_714,
Rattus norvegicus	ENSRNOG00000050585	7 retrocopies	retro_rnor_1669, retro_rnor_2241, retro_rnor_2275, retro_rnor_2361, retro_rnor_2568, retro_rnor_691, retro_rnor_703,
Sarcophilus harrisii	ENSSHAG00000018230	1 retrocopy	retro_shar_323,
Sus scrofa	ENSSSCG00000010517	1 retrocopy	retro_sscr_373,
Ictidomys tridecemlineatus	ENSSTOG00000025955	1 retrocopy	retro_itri_1187,
Tupaia belangeri	ENSTBEG00000005913	5 retrocopies	retro_tbel_1677, retro_tbel_1708, retro_tbel_2756, retro_tbel_3667, retro_tbel_563,
Drosophila melanogaster	FBgn0014869	1 retrocopy	retro_dmel_57,