RetrogeneDB ID:

retro_hsap_984

Retrocopy
location
Organism:Human (Homo sapiens)
Coordinates:12:32160090..32160363(+)
Located in intron of:None
Retrocopy
information
Ensembl ID:ENSG00000257094
Aliases:None
Status:KNOWN_PSEUDOGENE
Parental gene
information
Parental gene summary:
Parental gene symbol:CMC1
Ensembl ID:ENSG00000187118
Aliases:None
Description:COX assembly mitochondrial protein 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28783]


Retrocopy-Parental alignment summary:






>retro_hsap_984
GAAAAAGATATTTTGAGCCCTAAAATAATGAGAAAACAGGACAGAGAGAGGTGTTCTGAGCCAGTTCCAGATTTTGCCAA
CTGTTGCAAGAACTCTAGAATCTTTATGTTAGTAAAATGCCAAAAATAAAAGTCTGCATTGAAAGAACGTCTAACCACTT
ACTATAATCCAACCTTTTAGGAAGAATGCAAAATGGCATACATGAAGAAGAGTGAAGAATCCAGAAAAACTGGAATTCCT
ACAAAGAAAAGTCTATAGAAACGTCCCAAAAGC

ORF - retro_hsap_984 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 66.3 %
Parental protein coverage: 86.79 %
Number of stop codons detected: 3
Number of frameshifts detected 0


Retrocopy - Parental Gene Alignment:

ParentalEKDVLIPKIMREKAKERCSEQVQDFTKCCKNSGVLMVVKCRKENSALKECLTAYYNDPAFYEECKMEYLK
EKD.L.PKIMR....ERCSE.V.DF..CCKNS...M.VKC.K..SALKE.LT.YYN.P.F.EECKM.Y.K
RetrocopyEKDILSPKIMRKQDRERCSEPVPDFANCCKNSRIFMLVKCQK*KSALKERLTTYYN-PTF*EECKMAYMK
ParentalEREEFRKTGIPTKKRLQKLPTS
..EE.RKTGIPTKK.L.K.P.S
RetrocopyKSEESRKTGIPTKKSL*KRPKS

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
bodymap2_adipose 0 .04 RPM 6 .04 RPM
bodymap2_adrenal 0 .27 RPM 19 .73 RPM
bodymap2_brain 0 .00 RPM 7 .76 RPM
bodymap2_breast 0 .04 RPM 11 .48 RPM
bodymap2_colon 0 .12 RPM 11 .08 RPM
bodymap2_heart 0 .00 RPM 11 .72 RPM
bodymap2_kidney 0 .00 RPM 18 .94 RPM
bodymap2_liver 0 .00 RPM 10 .98 RPM
bodymap2_lung 0 .00 RPM 17 .14 RPM
bodymap2_lymph_node 0 .18 RPM 26 .09 RPM
bodymap2_ovary 0 .00 RPM 9 .54 RPM
bodymap2_prostate 0 .00 RPM 9 .47 RPM
bodymap2_skeletal_muscle 0 .00 RPM 3 .06 RPM
bodymap2_testis 0 .00 RPM 20 .15 RPM
bodymap2_thyroid 0 .00 RPM 7 .12 RPM
bodymap2_white_blood_cells 0 .16 RPM 33 .71 RPM
RNA Polymerase II actvity near the 5' end of retro_hsap_984 was not detected
No EST(s) were mapped for retro_hsap_984 retrocopy.
No TSS is located nearby retro_hsap_984 retrocopy 5' end.
retro_hsap_984 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_hsap_984 has 3 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Pan troglodytes retro_ptro_763
Gorilla gorilla retro_ggor_786
Pongo abelii retro_pabe_833

Parental genes homology:
Parental genes homology involve 15 parental genes, and 39 retrocopies.

Species Parental gene accession Retrocopies number
Callithrix jacchus ENSCJAG000000042722 retrocopies
Dasypus novemcinctus ENSDNOG000000189232 retrocopies
Homo sapiens ENSG00000187118 4 retrocopies
Gorilla gorilla ENSGGOG000000124064 retrocopies
Microcebus murinus ENSMICG000000117022 retrocopies
Myotis lucifugus ENSMLUG000000000442 retrocopies
Nomascus leucogenys ENSNLEG000000040664 retrocopies
Oryctolagus cuniculus ENSOCUG000000127932 retrocopies
Ochotona princeps ENSOPRG000000094741 retrocopy
Pongo abelii ENSPPYG000000140544 retrocopies
Pan troglodytes ENSPTRG000000147064 retrocopies
Rattus norvegicus ENSRNOG000000101491 retrocopy
Sorex araneus ENSSARG000000016291 retrocopy
Tupaia belangeri ENSTBEG000000025734 retrocopies
Tarsius syrichta ENSTSYG000000113712 retrocopies

Expression level across human populations :
image/svg+xml GBR_HG00142 GBR_HG00099 GBR_HG00114 GBR_HG00143 GBR_HG00131 GBR_HG00137 GBR_HG00133 GBR_HG00119 GBR_HG00111 GBR_HG00134 FIN_HG00378 FIN_HG00338 FIN_HG00349 FIN_HG00375 FIN_HG00315 FIN_HG00277 FIN_HG00328 FIN_HG00321 FIN_HG00377 FIN_HG00183 TSI_NA20756 TSI_NA20538 TSI_NA20798 TSI_NA20532 TSI_NA20765 TSI_NA20518 TSI_NA20513 TSI_NA20512 TSI_NA20771 TSI_NA20786 YRI_NA19114 YRI_NA19099 YRI_NA18870 YRI_NA18907 YRI_NA19223 YRI_NA19214 YRI_NA18916 YRI_NA19093 YRI_NA19118 YRI_NA19213 Toscaniin Italia: Finnish inFinland: British in England and Scotland: Utah Residents (CEPH) with Northernand Western European Ancestry: Yoruba in Ibadan, Nigeria: CEU_NA12760 CEU_NA12827 CEU_NA12872 CEU_NA12751 CEU_NA12873 CEU_NA12400 CEU_NA11930 CEU_NA12004 CEU_NA11831 CEU_NA11843 No expression ( = 0 RPM ) > 0 RPM = 0.06 RPM Legend:


Library Retrogene expression
CEU_NA11831 0 .00 RPM
CEU_NA11843 0 .00 RPM
CEU_NA11930 0 .03 RPM
CEU_NA12004 0 .00 RPM
CEU_NA12400 0 .00 RPM
CEU_NA12751 0 .02 RPM
CEU_NA12760 0 .00 RPM
CEU_NA12827 0 .00 RPM
CEU_NA12872 0 .00 RPM
CEU_NA12873 0 .00 RPM
FIN_HG00183 0 .03 RPM
FIN_HG00277 0 .00 RPM
FIN_HG00315 0 .00 RPM
FIN_HG00321 0 .03 RPM
FIN_HG00328 0 .00 RPM
FIN_HG00338 0 .06 RPM
FIN_HG00349 0 .00 RPM
FIN_HG00375 0 .00 RPM
FIN_HG00377 0 .00 RPM
FIN_HG00378 0 .04 RPM
GBR_HG00099 0 .00 RPM
GBR_HG00111 0 .00 RPM
GBR_HG00114 0 .00 RPM
GBR_HG00119 0 .00 RPM
GBR_HG00131 0 .00 RPM
GBR_HG00133 0 .00 RPM
GBR_HG00134 0 .02 RPM
GBR_HG00137 0 .03 RPM
GBR_HG00142 0 .03 RPM
GBR_HG00143 0 .00 RPM
TSI_NA20512 0 .03 RPM
TSI_NA20513 0 .00 RPM
TSI_NA20518 0 .00 RPM
TSI_NA20532 0 .00 RPM
TSI_NA20538 0 .00 RPM
TSI_NA20756 0 .03 RPM
TSI_NA20765 0 .02 RPM
TSI_NA20771 0 .00 RPM
TSI_NA20786 0 .00 RPM
TSI_NA20798 0 .00 RPM
YRI_NA18870 0 .00 RPM
YRI_NA18907 0 .00 RPM
YRI_NA18916 0 .00 RPM
YRI_NA19093 0 .00 RPM
YRI_NA19099 0 .00 RPM
YRI_NA19114 0 .00 RPM
YRI_NA19118 0 .00 RPM
YRI_NA19213 0 .02 RPM
YRI_NA19214 0 .00 RPM
YRI_NA19223 0 .00 RPM


Indel association:

No indels were associated with its genomic coordinates. Based on Kabza et al. 2015 (PubMed).




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