RetrogeneDB ID: retro_mmul_2424

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 9:109234849..109235327(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.9701
• Ensembl ID: ENSMMUG00000022291
• Aliases: None
• Description: transcription factor BTF3 [Source:RefSeq peptide;Acc:NP_001248021]

Sequence

>retro_mmul_2424
AGGATGAAAGAGATTATCATGAACTGGGAAAAACTTGCCAAACTAGAATCATAAGTGTGCAACAGTGAAAAAATAATTGC
TAGCAGAAAGAAAATGGTTCATAGAACATCTATAGCAAATAATTAAAAGCTTGGTTCTCCTTAAAGAAGTTAGAGGTCAA
CAATATTTCTGGTATCAAAGAGGGGAATATGTGTACAAACCAAAGAATGGTGATGTACTTTAACAATGCTCTAGGTCAGG
CATCTCTAGCAGTGAACACTACTATTACAGGCCATGCTGAGACAAAGCAGCTGAGACAAATGCTGCCCAGCATCTTAAAC
CAGCTTGGTACAGACAATCTGACTAGTTAAGGGAGACTGACAAGTTATTCTGTTCAAATAATCTAGGGGATGGAAAAGCA
TTTGCTACTGGAGATAATAATGAGGATGAAGTCCCAGATCTTGGGGAGGATTTTGATGAGGCTTCCAAGAATAAGGCA

Alignment

ORF - retro_mmul_2424 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 60.24 %
• Parental protein coverage: 78.85 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  QMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQ-FSLKKLGVNNISGIEEASVNMFT
          .MKE.IMN.EKLAKL...V....K..A.RKK..VHRT..A...KL..FSLKKL.VNNISGI.E...NM.T
Retrocopy RMKEIIMNWEKLAKLES*VCNSEKIIASRKK-MVHRTSIANN*KLG<FSLKKLEVNNISGIKEG--NMCT

Parental  NQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTS-LRRLAEALPKQSVDGKAP
          NQ..V..FNN...QASLA.NT.TITGHAETKQL..MLPSILNQLG.D.LTS.LR................
Retrocopy NQRMVMYFNNALGQASLAVNT-TITGHAETKQLRQMLPSILNQLGTDNLTS<LRETDKLFCSNNLGDGKA

Parental  LATGEDDDDEVPDLVENFDEASKNEA
          .ATG....DEVPDL.E.FDEASKN.A
Retrocopy FATGDNNEDEVPDLGEDFDEASKNKA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	9.08 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	25.39 RPM
SRP007412_cerebellum	0.00 RPM	6.78 RPM
SRP007412_heart	0.00 RPM	12.07 RPM
SRP007412_kidney	0.00 RPM	7.98 RPM
SRP007412_liver	0.00 RPM	7.80 RPM
SRP007412_testis	0.00 RPM	13.08 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2424 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2424 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2424 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_625

---

Parental genes homology:

Parental genes homology involve 24 parental genes, and 171 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000011563	14 retrocopies	retro_amel_1257, retro_amel_1279, retro_amel_1324, retro_amel_1334, retro_amel_1433, retro_amel_166, retro_amel_1769, retro_amel_182, retro_amel_1841, retro_amel_480, retro_amel_513, retro_amel_784, retro_amel_908, retro_amel_986,
Bos taurus	ENSBTAG00000010012	5 retrocopies	retro_btau_1161, retro_btau_1344, retro_btau_1361, retro_btau_459, retro_btau_551,
Choloepus hoffmanni	ENSCHOG00000001861	13 retrocopies	retro_chof_1027, retro_chof_1166, retro_chof_117, retro_chof_1397, retro_chof_1406, retro_chof_1884, retro_chof_1960, retro_chof_2194, retro_chof_2682, retro_chof_2703, retro_chof_344, retro_chof_364, retro_chof_700,
Callithrix jacchus	ENSCJAG00000016600	4 retrocopies	retro_cjac_1454, retro_cjac_1673, retro_cjac_2640, retro_cjac_281,
Cavia porcellus	ENSCPOG00000012832	1 retrocopy	retro_cpor_81,
Ciona savignyi	ENSCSAVG00000009653	1 retrocopy	retro_csav_25,
Dasypus novemcinctus	ENSDNOG00000018682	4 retrocopies	retro_dnov_1958, retro_dnov_2107, retro_dnov_497, retro_dnov_817,
Equus caballus	ENSECAG00000021629	1 retrocopy	retro_ecab_200,
Felis catus	ENSFCAG00000023973	10 retrocopies	retro_fcat_1044, retro_fcat_1378, retro_fcat_1438, retro_fcat_187, retro_fcat_188, retro_fcat_225, retro_fcat_28, retro_fcat_419, retro_fcat_593, retro_fcat_919,
Homo sapiens	ENSG00000145741	11 retrocopies	retro_hsap_1215, retro_hsap_1396, retro_hsap_2259, retro_hsap_2525, retro_hsap_2819, retro_hsap_2964, retro_hsap_3533, retro_hsap_3551, retro_hsap_3972, retro_hsap_4270, retro_hsap_625,
Microcebus murinus	ENSMICG00000017182	3 retrocopies	retro_mmur_1219, retro_mmur_1301, retro_mmur_651,
Myotis lucifugus	ENSMLUG00000012912	11 retrocopies	retro_mluc_1024, retro_mluc_1349, retro_mluc_1459, retro_mluc_1748, retro_mluc_1820, retro_mluc_1823, retro_mluc_2560, retro_mluc_2602, retro_mluc_482, retro_mluc_682, retro_mluc_694,
Macaca mulatta	ENSMMUG00000003636	1 retrocopy	retro_mmul_59,
Macaca mulatta	ENSMMUG00000022291	2 retrocopies	retro_mmul_105, retro_mmul_2424 ,
Monodelphis domestica	ENSMODG00000001762	3 retrocopies	retro_mdom_189, retro_mdom_454, retro_mdom_931,
Mustela putorius furo	ENSMPUG00000005864	28 retrocopies	retro_mputfur_1125, retro_mputfur_1149, retro_mputfur_1267, retro_mputfur_1289, retro_mputfur_1319, retro_mputfur_1321, retro_mputfur_1386, retro_mputfur_1414, retro_mputfur_1472, retro_mputfur_1525, retro_mputfur_1548, retro_mputfur_1576, retro_mputfur_1599, retro_mputfur_246, retro_mputfur_324, retro_mputfur_392, retro_mputfur_403, retro_mputfur_431, retro_mputfur_618, retro_mputfur_661, retro_mputfur_724, retro_mputfur_728, retro_mputfur_753, retro_mputfur_760, retro_mputfur_795, retro_mputfur_901, retro_mputfur_926, retro_mputfur_972,
Mus musculus	ENSMUSG00000021660	11 retrocopies	retro_mmus_1904, retro_mmus_2445, retro_mmus_2769, retro_mmus_3054, retro_mmus_3272, retro_mmus_3344, retro_mmus_3525, retro_mmus_443, retro_mmus_451, retro_mmus_470, retro_mmus_707,
Nomascus leucogenys	ENSNLEG00000004718	9 retrocopies	retro_nleu_1081, retro_nleu_1199, retro_nleu_1284, retro_nleu_1446, retro_nleu_1797, retro_nleu_2526, retro_nleu_451, retro_nleu_496, retro_nleu_734,
Pan troglodytes	ENSPTRG00000016979	12 retrocopies	retro_ptro_1470, retro_ptro_1599, retro_ptro_1675, retro_ptro_1912, retro_ptro_2006, retro_ptro_2413, retro_ptro_2494, retro_ptro_2697, retro_ptro_2896, retro_ptro_455, retro_ptro_832, retro_ptro_959,
Pteropus vampyrus	ENSPVAG00000007160	11 retrocopies	retro_pvam_1011, retro_pvam_241, retro_pvam_301, retro_pvam_440, retro_pvam_456, retro_pvam_515, retro_pvam_602, retro_pvam_647, retro_pvam_70, retro_pvam_882, retro_pvam_919,
Sorex araneus	ENSSARG00000007736	5 retrocopies	retro_sara_195, retro_sara_279, retro_sara_354, retro_sara_427, retro_sara_74,
Tarsius syrichta	ENSTSYG00000001295	7 retrocopies	retro_tsyr_1360, retro_tsyr_1388, retro_tsyr_212, retro_tsyr_707, retro_tsyr_878, retro_tsyr_90, retro_tsyr_954,
Tursiops truncatus	ENSTTRG00000007290	2 retrocopies	retro_ttru_1883, retro_ttru_391,
Vicugna pacos	ENSVPAG00000009607	2 retrocopies	retro_vpac_185, retro_vpac_467,