RetrogeneDB ID: retro_chof_2135

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_525:21325..22149(+)
• Located in intron of: ENSCHOG00000011055

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HNRNPA2B1
• Ensembl ID: ENSCHOG00000013832
• Aliases: None
• Description: heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:5033]

Sequence

>retro_chof_2135
AAGGAATCAGAGCAGTTGAGAAAACTGTTTATTGGTGGTCTGAGCTCTGAAACTATGGATGATAGTTTAGAAGAACACTG
TGAGAAATGAAGCACACTCACAGATTGTATGGTGATGAGAGACCCCCAAACAAAATGTTCCAGAAGCTTTGGTTTTGTTA
CTTACTCTTGTGTTGAAGAGGTGGGTGCAGCAATGTGTGCTTGACCACACAAGGTTGATGGGTGTGTAGAGGAACCAAAG
AGAGTTGCTCTAGAGAAGCTTCTGTAAAGCCTGGTGCCCCTCTAACAGTGAAGAAAAACTTTTGTTGGTGGTATTAAAGG
AGATACAGAAGAATATAATTTGAGAGACTACTTTGAAAAGTCTAGCAAGACTGAAGCCAAAGAAGTTATGGAAGACAGAC
AGAGTGGGAAAAAGAGAGAATCTGCTTTTGTGATTTTGAATAATCACGATACAGTTGATAAAACTGTTGTTCAGAAATAT
TACAGTATTAATGGGCATAACTGTGAAGTGAAAAAGGCCCTTTCTAAACAAGAGATGGCAGTCTGCTGGACCACAGAGAT
CGTGGAGGTGGATCTGACAACTCTATGGGCCCTGGAGGGATCTCTGGAGGTGGTGGAGGGAACTTTGGCCAAAGTGGAAA
CTTTGGTGGAAGAGGAGGCTATGGTGGGGCAGGTCGTGGCAGCAGAAGCAGTCATGGAAGAGGTGATGGTGGATATAATG
GATTTAGAGGTGATAGTGGCAGCTATGGCAGTGGTCCTGGTTATAGCAGAGGGGGCTATGGTGGTGGTAGACCAGGATAT
GGAAACCGAGGTCATGGTAGTGGA

Alignment

ORF - retro_chof_2135 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 55.36 %
• Parental protein coverage: 79.59 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  REKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRG-GFVTFSSMAEVDAAMAARPH
          .E.EQ.RKLFIGGLS.ET...SL....E....LTDC.VMRDP..K.SR..GFVT.S...EV.AAM.A.PH
Retrocopy KESEQLRKLFIGGLSSETMDDSLEEHCEK*STLTDCMVMRDPQTKCSRSFGFVTYSCVEEVGAAMCA*PH

Parental  SIDGRVVEPKR-AVAREESGKPGAHVTVK-KLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKK
          ..DG.V.EPKR....RE.S.KPGA..TVK.K.FVGGIK.DTEE..LRDYFE...K....E...DRQSGKK
Retrocopy KVDGCVEEPKR<SCSREASVKPGAPLTVK>KTFVGGIKGDTEEYNLRDYFEKSSKTEAKEVMEDRQSGKK

Parental  RGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEM-QEVQSSRS-GRGGNFGFGDSRGGGGNFG
          R...FV....HD.VDK.V.QKY..INGHN.EV.KALS.QEM.Q.....RS.G.G.....G.....GG..G
Retrocopy RESAFVILNNHDTVDKTVVQKYYSINGHNCEVKKALSKQEM>QSAGPQRS>GGGSDNSMGPGGISGGGGG

Parental  PGPGSNFRGGSDGY-GSGRG----FGDGYNGYGGGPG-GGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYG
          ....S...GG..GY.G.GRG.....G.G..GY.G..G..G..G..PGY...RGGYGGG.PGYGN.G.G.G
Retrocopy NFGQSGNFGGRGGYGGAGRGSRSSHGRGDGGYNGFRGDSGSYGSGPGY--SRGGYGGGRPGYGNRGHGSG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2135 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 58 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005726	4 retrocopies	retro_btau_1330, retro_btau_1535, retro_btau_193, retro_btau_228,
Choloepus hoffmanni	ENSCHOG00000000160	8 retrocopies	retro_chof_115, retro_chof_1470, retro_chof_2108, retro_chof_2370, retro_chof_533, retro_chof_59, retro_chof_741, retro_chof_890,
Choloepus hoffmanni	ENSCHOG00000003275	2 retrocopies	retro_chof_1578, retro_chof_18,
Choloepus hoffmanni	ENSCHOG00000013832	15 retrocopies	retro_chof_1060, retro_chof_1191, retro_chof_1413, retro_chof_1460, retro_chof_1507, retro_chof_2062, retro_chof_2135 , retro_chof_2235, retro_chof_2263, retro_chof_2404, retro_chof_2425, retro_chof_2473, retro_chof_2574, retro_chof_499, retro_chof_853,
Ciona intestinalis	ENSCING00000004062	1 retrocopy	retro_cint_7,
Callithrix jacchus	ENSCJAG00000007908	2 retrocopies	retro_cjac_2285, retro_cjac_3041,
Ciona savignyi	ENSCSAVG00000000472	1 retrocopy	retro_csav_26,
Dasypus novemcinctus	ENSDNOG00000012928	1 retrocopy	retro_dnov_1978,
Dipodomys ordii	ENSDORG00000005482	1 retrocopy	retro_dord_489,
Echinops telfairi	ENSETEG00000018577	1 retrocopy	retro_etel_1368,
Felis catus	ENSFCAG00000027765	1 retrocopy	retro_fcat_692,
Macropus eugenii	ENSMEUG00000001084	2 retrocopies	retro_meug_1897, retro_meug_214,
Myotis lucifugus	ENSMLUG00000007578	1 retrocopy	retro_mluc_34,
Mus musculus	ENSMUSG00000004980	1 retrocopy	retro_mmus_573,
Oryctolagus cuniculus	ENSOCUG00000026859	2 retrocopies	retro_ocun_1205, retro_ocun_642,
Otolemur garnettii	ENSOGAG00000015353	3 retrocopies	retro_ogar_1384, retro_ogar_3077, retro_ogar_3189,
Ochotona princeps	ENSOPRG00000011698	2 retrocopies	retro_opri_165, retro_opri_893,
Rattus norvegicus	ENSRNOG00000011175	3 retrocopies	retro_rnor_1824, retro_rnor_2043, retro_rnor_2339,
Ictidomys tridecemlineatus	ENSSTOG00000006202	3 retrocopies	retro_itri_1723, retro_itri_448, retro_itri_717,
Tursiops truncatus	ENSTTRG00000000709	3 retrocopies	retro_ttru_1066, retro_ttru_1204, retro_ttru_1788,
Vicugna pacos	ENSVPAG00000010417	1 retrocopy	retro_vpac_616,