RetrogeneDB ID: retro_mmus_1685

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 18:7581515..7581920(+)
• Located in intron of: ENSMUSG00000057440

Retrocopy information

• Ensembl ID: ENSMUSG00000094334
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Fabp5
• Ensembl ID: ENSMUSG00000027533
• Aliases: Fabp5, E-FABP, Fabpe, Klbp, PA-FABP, mal1
• Description: fatty acid binding protein 5, epidermal [Source:MGI Symbol;Acc:MGI:101790]

Sequence

>retro_mmus_1685
ATGGCCAGCCTTAAGGATCTCGAAGGGAAGTGGCGCCTGCTGGAAAGCCACAGCTTTGAGGAGTACATGAAAGAGCTAGG
AGTAGGACTGGCTCTTAGGAAGATGGCTGCCATGGCCAAGTCAGACTGTATCATTATTTGTGATGGCAACAACATCACCT
TCAAAACCGAGAGCACAGTGAAGACGACCGTGTTCTCTTGTACCCTGGGAGAGAAGTTTGATGAAACTACGGCTGATGGC
AGAAAAACTGAGACGGTCTGCACCTTCCAAGACGGTGCCCTGATCCAGCACCAGCAATGGGAAGGGAAGGAGAGCACGGT
AACAGGAAATCTGAAGGATGCGAAGATGACTGTGGAGCGTGTCACGAACAATGCCACCTGCACTCGGCTCTACGAGAAGG
TGCAA

Alignment

ORF - retro_mmus_1685 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.15 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MASLKDLEGKWRLMESHGFEEYMKELGVGLALRKMAAMAKPDCIITCDGNNITVKTESTVKTTVFSCNLG
          MASLKDLEGKWRL.ESH.FEEYMKELGVGLALRKMAAMAK.DCII.CDGNNIT.KTESTVKTTVFSC.LG
Retrocopy MASLKDLEGKWRLLESHSFEEYMKELGVGLALRKMAAMAKSDCIIICDGNNITFKTESTVKTTVFSCTLG

Parental  EKFDETTADGRKTETVCTFQDGALVQHQQWDGKESTITRKLKDGKMIVECVMNNATCTRVYEKVQ
          EKFDETTADGRKTETVCTFQDGAL.QHQQW.GKEST.T..LKD.KM.VE.V.NNATCTR.YEKVQ
Retrocopy EKFDETTADGRKTETVCTFQDGALIQHQQWEGKESTVTGNLKDAKMTVERVTNNATCTRLYEKVQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	38.01 RPM
SRP007412_cerebellum	0.09 RPM	22.10 RPM
SRP007412_heart	0.00 RPM	21.95 RPM
SRP007412_kidney	0.02 RPM	7.80 RPM
SRP007412_liver	0.00 RPM	16.77 RPM
SRP007412_testis	0.00 RPM	3.20 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_1685 was not detected

EST

No EST(s) were mapped for retro_mmus_1685 retrocopy.

TSS

No TSS is located nearby retro_mmus_1685 retrocopy 5' end.

Lab

retro_mmus_1685 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_1685 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 28 parental genes, and 116 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000014619	1 retrocopy	retro_amel_1139,
Bos taurus	ENSBTAG00000047330	3 retrocopies	retro_btau_1312, retro_btau_1828, retro_btau_886,
Callithrix jacchus	ENSCJAG00000000444	4 retrocopies	retro_cjac_1832, retro_cjac_2227, retro_cjac_2816, retro_cjac_4084,
Cavia porcellus	ENSCPOG00000025732	1 retrocopy	retro_cpor_948,
Dasypus novemcinctus	ENSDNOG00000018066	5 retrocopies	retro_dnov_1073, retro_dnov_1231, retro_dnov_1318, retro_dnov_2392, retro_dnov_559,
Equus caballus	ENSECAG00000008270	2 retrocopies	retro_ecab_894, retro_ecab_938,
Erinaceus europaeus	ENSEEUG00000014023	2 retrocopies	retro_eeur_405, retro_eeur_627,
Echinops telfairi	ENSETEG00000007443	14 retrocopies	retro_etel_1024, retro_etel_1241, retro_etel_1276, retro_etel_1405, retro_etel_1467, retro_etel_1706, retro_etel_1842, retro_etel_1904, retro_etel_2003, retro_etel_512, retro_etel_602, retro_etel_620, retro_etel_806, retro_etel_994,
Felis catus	ENSFCAG00000006032	2 retrocopies	retro_fcat_1243, retro_fcat_1834,
Homo sapiens	ENSG00000164687	12 retrocopies	retro_hsap_1205, retro_hsap_1279, retro_hsap_1520, retro_hsap_1521, retro_hsap_2167, retro_hsap_2568, retro_hsap_3000, retro_hsap_3357, retro_hsap_3376, retro_hsap_3811, retro_hsap_4717, retro_hsap_880,
Gorilla gorilla	ENSGGOG00000005964	8 retrocopies	retro_ggor_1005, retro_ggor_1163, retro_ggor_2079, retro_ggor_2276, retro_ggor_2284, retro_ggor_2563, retro_ggor_2931, retro_ggor_940,
Latimeria chalumnae	ENSLACG00000008511	3 retrocopies	retro_lcha_37, retro_lcha_45, retro_lcha_57,
Macropus eugenii	ENSMEUG00000002136	1 retrocopy	retro_meug_1874,
Microcebus murinus	ENSMICG00000001311	2 retrocopies	retro_mmur_137, retro_mmur_702,
Myotis lucifugus	ENSMLUG00000009514	3 retrocopies	retro_mluc_1590, retro_mluc_1920, retro_mluc_501,
Macaca mulatta	ENSMMUG00000000486	4 retrocopies	retro_mmul_1417, retro_mmul_1920, retro_mmul_2095, retro_mmul_2230,
Mus musculus	ENSMUSG00000027533	4 retrocopies	retro_mmus_1685 , retro_mmus_1791, retro_mmus_2084, retro_mmus_3185,
Mus musculus	ENSMUSG00000028773	3 retrocopies	retro_mmus_2804, retro_mmus_3204, retro_mmus_65,
Otolemur garnettii	ENSOGAG00000002413	10 retrocopies	retro_ogar_1024, retro_ogar_1151, retro_ogar_1286, retro_ogar_1676, retro_ogar_2873, retro_ogar_3066, retro_ogar_3099, retro_ogar_3265, retro_ogar_715, retro_ogar_878,
Oryzias latipes	ENSORLG00000008282	1 retrocopy	retro_olat_7,
Pongo abelii	ENSPPYG00000018699	1 retrocopy	retro_pabe_27,
Pan troglodytes	ENSPTRG00000020373	12 retrocopies	retro_ptro_1029, retro_ptro_1030, retro_ptro_1498, retro_ptro_1654, retro_ptro_2029, retro_ptro_2131, retro_ptro_2265, retro_ptro_2295, retro_ptro_2664, retro_ptro_3135, retro_ptro_823, retro_ptro_875,
Pteropus vampyrus	ENSPVAG00000017850	5 retrocopies	retro_pvam_1159, retro_pvam_467, retro_pvam_531, retro_pvam_852, retro_pvam_89,
Rattus norvegicus	ENSRNOG00000049075	3 retrocopies	retro_rnor_1762, retro_rnor_1879, retro_rnor_1997,
Sus scrofa	ENSSSCG00000006153	1 retrocopy	retro_sscr_476,
Ictidomys tridecemlineatus	ENSSTOG00000007877	3 retrocopies	retro_itri_1305, retro_itri_389, retro_itri_72,
Tarsius syrichta	ENSTSYG00000001472	5 retrocopies	retro_tsyr_126, retro_tsyr_1534, retro_tsyr_1894, retro_tsyr_1982, retro_tsyr_2024,
Tursiops truncatus	ENSTTRG00000005377	1 retrocopy	retro_ttru_1800,