RetrogeneDB ID: retro_rnor_2746

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 9:98277206..98277627(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSRNOG00000021435
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Ywhaq
• Ensembl ID: ENSRNOG00000008104
• Aliases: Ywhaq, 14-3-3t
• Description: 14-3-3 protein theta [Source:UniProtKB/Swiss-Prot;Acc:P68255]

Sequence

>retro_rnor_2746
ATAGCCAATGCAACTTAGTCCAGAGAGTAAGGTCTTCTATCTGAAAATGAAGGGAGATTATTTCCGGTGTCTTGCTGAAG
TAGCTTGTGGTGATGATCGAAAACAAACGATAGGAAATCCCCAAGGAGCCTACCAAGAGGCATTTGATATAAGCAAGAAA
GAGATGCAACTTACCCGTCCGATCCGCCTGGGGCTGGCTCTTCACTCTCCTGTATTTTACTATGAGAGCCTTAATAATCC
AGAGCCTGCCTACACACTGGCTAAAATGGCTTTTGATGAAGCAATTGCTGAGCTTGAAACACTGAATGAAGACTCCTACA
AAGACAGCGCCCTCGTCACACAGTTGCTTAGAGACAACTTAACATTATGGACATCAGACAGTGCAGGAGAAGAATGTGAT
GCAGCGGATGGGGCTGAGAAC

Alignment

ORF - retro_rnor_2746 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86.52 %
• Parental protein coverage: 57.14 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  IANAT-NPESKVFYLKMKGDYFRYLAEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNF
          IANAT..PESKVFYLKMKGDYFR.LAEVACGDDRKQTI.N.QGAYQEAFDISKKEMQ.T.PIRLGLAL..
Retrocopy IANAT>SPESKVFYLKMKGDYFRCLAEVACGDDRKQTIGNPQGAYQEAFDISKKEMQLTRPIRLGLALHS

Parental  SVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAE
          .VFYYE.LNNPE.A.TLAK.AFDEAIAEL.TLNEDSYKDS.L..QLLRDNLTLWTSDSAGEECDAA.GAE
Retrocopy PVFYYESLNNPEPAYTLAKMAFDEAIAELETLNEDSYKDSALVTQLLRDNLTLWTSDSAGEECDAADGAE

Parental  N
          N
Retrocopy N

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.14 RPM	218.35 RPM
SRP017611_kidney	0.07 RPM	124.28 RPM
SRP017611_liver	0.07 RPM	31.00 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_2746 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_2746 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_2746 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 84 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000008618	4 retrocopies	retro_amel_1214, retro_amel_1382, retro_amel_1837, retro_amel_917,
Bos taurus	ENSBTAG00000002108	2 retrocopies	retro_btau_1180, retro_btau_86,
Choloepus hoffmanni	ENSCHOG00000004661	13 retrocopies	retro_chof_136, retro_chof_1427, retro_chof_1605, retro_chof_1835, retro_chof_2026, retro_chof_2115, retro_chof_2134, retro_chof_2233, retro_chof_429, retro_chof_481, retro_chof_489, retro_chof_527, retro_chof_863,
Callithrix jacchus	ENSCJAG00000006394	2 retrocopies	retro_cjac_2197, retro_cjac_3127,
Cavia porcellus	ENSCPOG00000011321	4 retrocopies	retro_cpor_135, retro_cpor_1463, retro_cpor_616, retro_cpor_668,
Equus caballus	ENSECAG00000004925	1 retrocopy	retro_ecab_134,
Echinops telfairi	ENSETEG00000015359	4 retrocopies	retro_etel_1027, retro_etel_1048, retro_etel_235, retro_etel_65,
Felis catus	ENSFCAG00000007854	2 retrocopies	retro_fcat_1702, retro_fcat_771,
Homo sapiens	ENSG00000134308	2 retrocopies	retro_hsap_3004, retro_hsap_8,
Gorilla gorilla	ENSGGOG00000001569	1 retrocopy	retro_ggor_2081,
Macropus eugenii	ENSMEUG00000014442	7 retrocopies	retro_meug_1122, retro_meug_1208, retro_meug_1259, retro_meug_1549, retro_meug_1918, retro_meug_2106, retro_meug_538,
Myotis lucifugus	ENSMLUG00000005383	1 retrocopy	retro_mluc_1817,
Monodelphis domestica	ENSMODG00000014740	1 retrocopy	retro_mdom_1339,
Mustela putorius furo	ENSMPUG00000013252	2 retrocopies	retro_mputfur_1132, retro_mputfur_730,
Mus musculus	ENSMUSG00000076432	10 retrocopies	retro_mmus_1076, retro_mmus_1378, retro_mmus_1926, retro_mmus_2250, retro_mmus_2299, retro_mmus_2471, retro_mmus_2689, retro_mmus_3250, retro_mmus_3308, retro_mmus_406,
Nomascus leucogenys	ENSNLEG00000013534	3 retrocopies	retro_nleu_2543, retro_nleu_750, retro_nleu_869,
Oryctolagus cuniculus	ENSOCUG00000010482	1 retrocopy	retro_ocun_1463,
Otolemur garnettii	ENSOGAG00000000547	3 retrocopies	retro_ogar_1047, retro_ogar_1732, retro_ogar_39,
Pongo abelii	ENSPPYG00000012663	4 retrocopies	retro_pabe_1165, retro_pabe_2490, retro_pabe_3391, retro_pabe_3511,
Pelodiscus sinensis	ENSPSIG00000012692	1 retrocopy	retro_psin_2,
Pan troglodytes	ENSPTRG00000011641	2 retrocopies	retro_ptro_2032, retro_ptro_3,
Pteropus vampyrus	ENSPVAG00000005334	1 retrocopy	retro_pvam_983,
Rattus norvegicus	ENSRNOG00000008104	5 retrocopies	retro_rnor_1569, retro_rnor_2065, retro_rnor_2123, retro_rnor_2180, retro_rnor_2746 ,
Sorex araneus	ENSSARG00000012476	4 retrocopies	retro_sara_1, retro_sara_162, retro_sara_179, retro_sara_23,
Tursiops truncatus	ENSTTRG00000000871	4 retrocopies	retro_ttru_1006, retro_ttru_1109, retro_ttru_1530, retro_ttru_1536,