RetrogeneDB ID: retro_lcha_24

Retrocopy location

• Organism: Coelacanth (Latimeria chalumnae)
• Coordinates: JH126571.1:1238129..1238528(+)
• Located in intron of: ENSLACG00000014935

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TPT1
• Ensembl ID: ENSLACG00000004306
• Aliases: None
• Description: None

Sequence

>retro_lcha_24
CTGATCGATGGGAATGCATCTTCTGAAGGTGGAGAAGATAATGAAGTGCAATCTACCACAATTAGTGGTGTAGATATTGT
ATTGAACCACAAGCTGCAAGAGACCAGCTTCCAGAAGGAAGCCTACAAAAAGTACCTGAAACAATACATGAAAGCCATTA
AAGAGAAACTTGACCAAGACGAGCCTGAGGGAGTCATTGACTTTAAGTGTGCACAATAGCAGGTCCAAGTCATTGTGGCC
AACTTCAAAAACTATCAGTTCTTCACAGGTGAGTCCATGAACCCAGGTTGCATGGTGGCTTTGCTAGGCTACCGTGAAGA
TGGCATCACCCCATACATGATCTTCTTTAAGGACAGGCTGGAAATCAAGAAACGTTAACATTTGTGCAAGACTCTAAGT

Alignment

ORF - retro_lcha_24 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.64 %
• Parental protein coverage: 70.53 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  LIGGNASSEVGEDGDLQSTTISGVDIVLNHKLQETGFQKETYTLYLKKYMKTIKEKLGEEKPERVNDFVK
          LI.GNASSE.GED...QSTTISGVDIVLNHKLQET.FQKE.Y..YLK.YMK.IKEKL....PE.V.DF.K
Retrocopy LIDGNASSEGGEDNEVQSTTISGVDIVLNHKLQETSFQKEAYKKYLKQYMKAIKEKLDQDEPEGVIDF-K

Parental  NAPQACKAIMANFKNYQFFTGESMNPDGMVALLDYREDGITPYMIFFKDGLEIEKCCCVCAVKS
          .A......I.ANFKNYQFFTGESMNP..MVALL.YREDGITPYMIFFKD.LEI.K....C...S
Retrocopy CAQ*QVQVIVANFKNYQFFTGESMNPGCMVALLGYREDGITPYMIFFKDRLEIKKR*HLCKTLS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
DRP000627_gill	0.00 RPM	780.23 RPM
DRP000627_kidney	0.00 RPM	712.60 RPM
DRP000627_pectoral_fin	0.00 RPM	1297.55 RPM
DRP000627_pelvic_fin	0.00 RPM	1558.08 RPM
DRP000627_pharynx	0.00 RPM	504.18 RPM
DRP000627_tail_muscle	0.00 RPM	381.97 RPM

ChIP-Seq

Latimeria chalumnae was not studied using ChIP-Seq data.

EST

Latimeria chalumnae was not studied using EST data.

TSS

Latimeria chalumnae was not studied using FANTOM5 data.

Lab

retro_lcha_24 was not experimentally validated.

Homology

Retrocopy orthology:

Latimeria chalumnae does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 34 parental genes, and 252 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000006531	2 retrocopies	retro_acar_156, retro_acar_58,
Ailuropoda melanoleuca	ENSAMEG00000013022	8 retrocopies	retro_amel_1153, retro_amel_1521, retro_amel_1593, retro_amel_1804, retro_amel_1878, retro_amel_472, retro_amel_569, retro_amel_969,
Bos taurus	ENSBTAG00000010156	2 retrocopies	retro_btau_21, retro_btau_235,
Canis familiaris	ENSCAFG00000004533	10 retrocopies	retro_cfam_1110, retro_cfam_1328, retro_cfam_1476, retro_cfam_1508, retro_cfam_1846, retro_cfam_254, retro_cfam_341, retro_cfam_483, retro_cfam_661, retro_cfam_777,
Callithrix jacchus	ENSCJAG00000019229	2 retrocopies	retro_cjac_1786, retro_cjac_314,
Cavia porcellus	ENSCPOG00000009278	12 retrocopies	retro_cpor_1053, retro_cpor_1215, retro_cpor_1273, retro_cpor_206, retro_cpor_248, retro_cpor_340, retro_cpor_536, retro_cpor_583, retro_cpor_602, retro_cpor_697, retro_cpor_917, retro_cpor_968,
Dasypus novemcinctus	ENSDNOG00000000653	22 retrocopies	retro_dnov_1071, retro_dnov_1202, retro_dnov_1349, retro_dnov_1705, retro_dnov_2082, retro_dnov_2283, retro_dnov_2305, retro_dnov_237, retro_dnov_2412, retro_dnov_2531, retro_dnov_2687, retro_dnov_276, retro_dnov_342, retro_dnov_397, retro_dnov_417, retro_dnov_453, retro_dnov_71, retro_dnov_847, retro_dnov_870, retro_dnov_909, retro_dnov_934, retro_dnov_981,
Dipodomys ordii	ENSDORG00000008518	2 retrocopies	retro_dord_370, retro_dord_471,
Equus caballus	ENSECAG00000018348	3 retrocopies	retro_ecab_337, retro_ecab_686, retro_ecab_727,
Echinops telfairi	ENSETEG00000003091	3 retrocopies	retro_etel_1337, retro_etel_1546, retro_etel_248,
Felis catus	ENSFCAG00000002107	8 retrocopies	retro_fcat_1366, retro_fcat_1544, retro_fcat_1996, retro_fcat_443, retro_fcat_553, retro_fcat_645, retro_fcat_735, retro_fcat_992,
Homo sapiens	ENSG00000133112	13 retrocopies	retro_hsap_1083, retro_hsap_2234, retro_hsap_2256, retro_hsap_2382, retro_hsap_2503, retro_hsap_3156, retro_hsap_3676, retro_hsap_3828, retro_hsap_3946, retro_hsap_4307, retro_hsap_4701, retro_hsap_4786, retro_hsap_678,
Gorilla gorilla	ENSGGOG00000001684	12 retrocopies	retro_ggor_1561, retro_ggor_1681, retro_ggor_1807, retro_ggor_2045, retro_ggor_2484, retro_ggor_2628, retro_ggor_2652, retro_ggor_2877, retro_ggor_2878, retro_ggor_2980, retro_ggor_584, retro_ggor_855,
Latimeria chalumnae	ENSLACG00000004306	2 retrocopies	retro_lcha_24 , retro_lcha_34,
Loxodonta africana	ENSLAFG00000021740	7 retrocopies	retro_lafr_1008, retro_lafr_1195, retro_lafr_1211, retro_lafr_1247, retro_lafr_347, retro_lafr_484, retro_lafr_883,
Microcebus murinus	ENSMICG00000002027	9 retrocopies	retro_mmur_102, retro_mmur_1060, retro_mmur_1163, retro_mmur_1627, retro_mmur_248, retro_mmur_318, retro_mmur_490, retro_mmur_641, retro_mmur_967,
Myotis lucifugus	ENSMLUG00000017709	1 retrocopy	retro_mluc_1332,
Macaca mulatta	ENSMMUG00000022979	2 retrocopies	retro_mmul_158, retro_mmul_85,
Monodelphis domestica	ENSMODG00000014940	2 retrocopies	retro_mdom_128, retro_mdom_9,
Mustela putorius furo	ENSMPUG00000001640	10 retrocopies	retro_mputfur_1043, retro_mputfur_30, retro_mputfur_364, retro_mputfur_565, retro_mputfur_574, retro_mputfur_582, retro_mputfur_677, retro_mputfur_870, retro_mputfur_960, retro_mputfur_967,
Mus musculus	ENSMUSG00000060126	8 retrocopies	retro_mmus_1643, retro_mmus_2193, retro_mmus_2354, retro_mmus_2862, retro_mmus_3264, retro_mmus_3371, retro_mmus_3483, retro_mmus_3496,
Nomascus leucogenys	ENSNLEG00000002108	8 retrocopies	retro_nleu_1262, retro_nleu_1281, retro_nleu_1637, retro_nleu_2127, retro_nleu_2539, retro_nleu_2540, retro_nleu_368, retro_nleu_9,
Oryctolagus cuniculus	ENSOCUG00000023692	2 retrocopies	retro_ocun_40, retro_ocun_75,
Otolemur garnettii	ENSOGAG00000012523	20 retrocopies	retro_ogar_1141, retro_ogar_1249, retro_ogar_1538, retro_ogar_1682, retro_ogar_1754, retro_ogar_2193, retro_ogar_2225, retro_ogar_2298, retro_ogar_2331, retro_ogar_2594, retro_ogar_2668, retro_ogar_2819, retro_ogar_2893, retro_ogar_2944, retro_ogar_344, retro_ogar_350, retro_ogar_3503, retro_ogar_622, retro_ogar_746, retro_ogar_906,
Procavia capensis	ENSPCAG00000016228	3 retrocopies	retro_pcap_245, retro_pcap_351, retro_pcap_357,
Pongo abelii	ENSPPYG00000005335	5 retrocopies	retro_pabe_1958, retro_pabe_2626, retro_pabe_2809, retro_pabe_83, retro_pabe_900,
Pteropus vampyrus	ENSPVAG00000003191	15 retrocopies	retro_pvam_1069, retro_pvam_1116, retro_pvam_1142, retro_pvam_1145, retro_pvam_1252, retro_pvam_1266, retro_pvam_1290, retro_pvam_1322, retro_pvam_1387, retro_pvam_242, retro_pvam_369, retro_pvam_547, retro_pvam_585, retro_pvam_721, retro_pvam_801,
Rattus norvegicus	ENSRNOG00000001049	7 retrocopies	retro_rnor_115, retro_rnor_2464, retro_rnor_2706, retro_rnor_411, retro_rnor_886, retro_rnor_908, retro_rnor_958,
Sorex araneus	ENSSARG00000009319	1 retrocopy	retro_sara_113,
Sarcophilus harrisii	ENSSHAG00000001545	1 retrocopy	retro_shar_227,
Ictidomys tridecemlineatus	ENSSTOG00000006931	7 retrocopies	retro_itri_1192, retro_itri_146, retro_itri_266, retro_itri_325, retro_itri_612, retro_itri_700, retro_itri_999,
Tupaia belangeri	ENSTBEG00000013539	25 retrocopies	retro_tbel_1009, retro_tbel_1556, retro_tbel_1634, retro_tbel_1724, retro_tbel_1725, retro_tbel_2086, retro_tbel_2100, retro_tbel_2265, retro_tbel_2278, retro_tbel_2464, retro_tbel_2550, retro_tbel_2767, retro_tbel_3238, retro_tbel_3354, retro_tbel_3403, retro_tbel_3410, retro_tbel_3592, retro_tbel_3888, retro_tbel_4226, retro_tbel_4400, retro_tbel_4526, retro_tbel_459, retro_tbel_4641, retro_tbel_4733, retro_tbel_830,
Tarsius syrichta	ENSTSYG00000003160	13 retrocopies	retro_tsyr_1054, retro_tsyr_1291, retro_tsyr_1549, retro_tsyr_1601, retro_tsyr_2120, retro_tsyr_314, retro_tsyr_655, retro_tsyr_763, retro_tsyr_781, retro_tsyr_784, retro_tsyr_890, retro_tsyr_958, retro_tsyr_990,
Vicugna pacos	ENSVPAG00000008472	5 retrocopies	retro_vpac_1, retro_vpac_101, retro_vpac_159, retro_vpac_539, retro_vpac_552,