RetrogeneDB ID:

retro_ptro_1051

Retrocopy
location
Organism:Chimpanzee (Pan troglodytes)
Coordinates:15:41108753..41109873(-)
Located in intron of:ENSPTRG00000007008
Retrocopy
information
Ensembl ID:None
Aliases:None
Status:NOVEL
Parental gene
information
Parental gene summary:
Parental gene symbol:ACTB
Ensembl ID:ENSPTRG00000018890
Aliases:ACTB, beta-actin
Description:Pan troglodytes actin, beta (ACTB), mRNA. [Source:RefSeq mRNA;Acc:NM_001009945]


Retrocopy-Parental alignment summary:






>retro_ptro_1051
ATGGATGATGATATCACCATGCTTGTCATCGACAATGGCTCTGGCATGTGCAAGGCCAGCTTTGCGGGTGATGATGCCCA
CCCCGGGCCATCTTCCCCTCCATTGTGGGGCGCCCCAGGCACCAGGGCGTGACGGTGGGCATGGGTCAGAAGGACTCCTA
TGTGGGCGACGAGGCCCAGAGCAGGAGAGGCATCCTGACCCTGAAGTACCCCATCAAGCAGGACATTGTCACCACCTGGG
ACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGTGTGTGGCTGCCAAGGAGCACCCCATGCTGCTGACC
AAGGTCCCCCTGAGCCCCAAGGCCAACCACAAGAAGATGACCCAGATCATGTTGGAGATCTTCGACAGGCCAGCCATGTA
CGTGGCCATCCAGGCCGTACTGTCCCTGTACACCTCTGGCCTACCACTGACATCATGATGGACTACGGTGACGGGGTCAC
CCACACTGTGCCCATCTATGAAGAGTATGCCCTCCCCCATGCCATCCTGCGTGTGGACGTGGCTGGTCAGGACCTGACTG
ACTACCTCATGAAGATCCTCACCTAGCACAGCTACATCTTCACCGCCACAGCCAAGCGGGAAATTGTGCATGACATCAAG
GAGAAGCTGTGCTATGTCACCCTGGACTTCGAGCAGGAGATGGCCATGGTGGCCTCCAGCTCCTCCCTGGAGATAGCTAC
AAGCTGCCCGACGGCCAGGTCATCATCATCAGCAAAAGCAGTTCTGCTGCCCTGAGGCGCTCTTCCAGCCTTCCTTCCTG
GGCATGGAATCCCACGGCATCCATGAAACTACCTTCAACTCCATCATGAAGTGTGATGTGGACATCCTCAAAGACCTGTA
TGCCAACACAGTGCTATCTGGCGGCACCACCACGTACCCTGGCATCGCCGATAGGATGCAGAAGATCACCACCCTGGCGC
CCACACAATGAAGATCAAGATCACTGCTCCTCCCAAGCGCAAGTACTCCGTGTGGATCGGCAGCTCCATCCTGGCCCGGC
TGTCCACCGTCCAGCAGATGTGGATCAGCAAGCAGGAATATGATGAGTCAGGCACCTCCATCATCCACCGCAGATGCTTC

ORF - retro_ptro_1051 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 80.05 %
Parental protein coverage: 100. %
Number of stop codons detected: 1
Number of frameshifts detected 5


Retrocopy - Parental Gene Alignment:

ParentalMDDDIAALVVDNGSGMCKAGFAGDDA-PRAVFPSI-VGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLK
MDDDI..LV.DNGSGMCKA.FAGDDA.P....P...VGRPRHQGV.VGMGQKDSYVGDEAQS.RGILTLK
RetrocopyMDDDITMLVIDNGSGMCKASFAGDDAHPGPSSPPL<VGRPRHQGVTVGMGQKDSYVGDEAQSRRGILTLK
ParentalYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQA
YPI...IVT.WDDMEKIWHHTFYNEL.VA..EHP.LLT..PL.PKAN..KMTQIM.E.F..PAMYVAIQA
RetrocopyYPIKQDIVTTWDDMEKIWHHTFYNELCVAAKEHPMLLTKVPLSPKANHKKMTQIMLEIFDRPAMYVAIQA
ParentalVLSLYASG-RTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAERE
VLSLY.SG..TT.I.MD.GDGVTHTVPIYE.YALPHAILR.D.AG.DLTDYLMKILT...Y.FT.TA.RE
RetrocopyVLSLYTSG<PTTDIMMDYGDGVTHTVPIYEEYALPHAILRVDVAGQDLTDYLMKILT*HSYIFTATAKRE
ParentalIVRDIKEKLCYVALDFEQEMATAASSSSLE-KSYELPDGQVITIG-NERFRCPEALFQPSFLGMESCGIH
IV.DIKEKLCYV.LDFEQEMA..ASSSSLE..SY.LPDGQVI.I.....F.CPEALFQPSFLGMES.GIH
RetrocopyIVHDIKEKLCYVTLDFEQEMAMVASSSSLE<DSYKLPDGQVIIIS<QKQFCCPEALFQPSFLGMESHGIH
ParentalETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPS-TMKIKIIAPPERKYSVWIGGS
ETTFNSIMKCDVDI.KDLYANTVLSGGTT.YPGIADRMQK.IT.LAP..TMKIKI.APP.RKYSVWIG.S
RetrocopyETTFNSIMKCDVDILKDLYANTVLSGGTTTYPGIADRMQK-ITTLAPT<TMKIKITAPPKRKYSVWIGSS
ParentalILASLSTFQQMWISKQEYDESGPSIVHRKCF
ILA.LST.QQMWISKQEYDESG.SI.HR.CF
RetrocopyILARLSTVQQMWISKQEYDESGTSIIHRRCF

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
SRP007412_brain_prefrontal_cortex 0 .55 RPM 1976 .36 RPM
SRP007412_cerebellum 0 .14 RPM 1129 .84 RPM
SRP007412_heart 0 .00 RPM 382 .11 RPM
SRP007412_kidney 0 .00 RPM 1474 .96 RPM
SRP007412_liver 0 .07 RPM 1774 .09 RPM
SRP007412_testis 0 .63 RPM 315 .31 RPM
Pan troglodytes was not studied using ChIP-Seq data.
No EST(s) were mapped for retro_ptro_1051 retrocopy.
Pan troglodytes was not studied using FANTOM5 data.
retro_ptro_1051 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_ptro_1051 has 3 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Homo sapiens retro_hsap_1563
Gorilla gorilla retro_ggor_1188
Pongo abelii retro_pabe_1292

Parental genes homology:
Parental genes homology involve 14 parental genes, and 45 retrocopies.

Species Parental gene accession Retrocopies number
Anas platyrhynchos ENSAPLG000000101471 retrocopy
Canis familiaris ENSCAFG000000160203 retrocopies
Callithrix jacchus ENSCJAG000000000082 retrocopies
Dipodomys ordii ENSDORG000000100791 retrocopy
Equus caballus ENSECAG000000159352 retrocopies
Felis catus ENSFCAG000000067881 retrocopy
Loxodonta africana ENSLAFG000000091671 retrocopy
Macaca mulatta ENSMMUG000000111531 retrocopy
Otolemur garnettii ENSOGAG000000083481 retrocopy
Petromyzon marinus ENSPMAG000000041611 retrocopy
Pan troglodytes ENSPTRG000000028941 retrocopy
Pan troglodytes ENSPTRG00000018890 27 retrocopies
Ictidomys tridecemlineatus ENSSTOG000000068682 retrocopies
Xenopus tropicalis ENSXETG000000251161 retrocopy



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