RetrogeneDB ID: retro_pabe_776

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 11:73309790..73310146(-)
• Located in intron of: ENSPPYG00000003713

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS20
• Ensembl ID: ENSPPYG00000018600
• Aliases: None
• Description: ribosomal protein S20 [Source:HGNC Symbol;Acc:10405]

Sequence

>retro_pabe_776
ATGGCTTTGAAGGTTACCGGAAAAACACGCGTGGAGCTGGAGGTGGCAATTCACTGAAATTGAATTACTCTAATGAGCCG
CAACATAAAATCCCTGGAAAAGGTGTGTGCTGACTTCATCAGAGGAGCAAAGGCAGAGAATCTCCAAGTGAAAGGACCAG
TTCGAATACCTACCAAGACTTTGAGAATCACTACAAGAAAAACTCCTTGTGGTGAAGGTTCTAAGACATGAGATCCTTTC
CAGATGAGGATCCACAAGCGACTCATTGACTTGCACAGTCCTTCTGAGATTGTTAAGCAGATTGCTTCCATCAGTTTGAG
CCAGGAGTTGAGGTGAAAGTCACCATTGCAGATGCT

Alignment

ORF - retro_pabe_776 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.33 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPC
          MA.K.TGKT.VE.EVAIH...ITL.SRN.KSLEKVCAD.IRGAK..NL.VKGPVR.PTKTLRITTRKTPC
Retrocopy MALKVTGKTRVELEVAIH*N*ITLMSRNIKSLEKVCADFIRGAKAENLQVKGPVRIPTKTLRITTRKTPC

Parental  GEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISI-EPGVEVEVTIADA
          GEGSKT.D.FQMRIHKRLIDLHSPSEIVKQI.SIS..EPGVEV.VTIADA
Retrocopy GEGSKT*DPFQMRIHKRLIDLHSPSEIVKQIASISL<EPGVEVKVTIADA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	91.06 RPM
SRP007412_cerebellum	0.00 RPM	60.68 RPM
SRP007412_heart	0.03 RPM	97.78 RPM
SRP007412_kidney	0.17 RPM	173.72 RPM
SRP007412_liver	0.12 RPM	152.92 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_776 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_776 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_776 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_899
Pan troglodytes	retro_ptro_620

---

Parental genes homology:

Parental genes homology involve 22 parental genes, and 304 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000019147	11 retrocopies	retro_btau_1082, retro_btau_1086, retro_btau_1250, retro_btau_1272, retro_btau_1274, retro_btau_1419, retro_btau_1526, retro_btau_1789, retro_btau_1818, retro_btau_454, retro_btau_632,
Canis familiaris	ENSCAFG00000029884	20 retrocopies	retro_cfam_1144, retro_cfam_1247, retro_cfam_1287, retro_cfam_1367, retro_cfam_1409, retro_cfam_1472, retro_cfam_1633, retro_cfam_1646, retro_cfam_1688, retro_cfam_1719, retro_cfam_1810, retro_cfam_1964, retro_cfam_1978, retro_cfam_1992, retro_cfam_2008, retro_cfam_2193, retro_cfam_559, retro_cfam_666, retro_cfam_672, retro_cfam_949,
Callithrix jacchus	ENSCJAG00000016631	4 retrocopies	retro_cjac_3017, retro_cjac_319, retro_cjac_667, retro_cjac_749,
Dipodomys ordii	ENSDORG00000005794	2 retrocopies	retro_dord_252, retro_dord_653,
Echinops telfairi	ENSETEG00000003394	3 retrocopies	retro_etel_16, retro_etel_1814, retro_etel_2067,
Felis catus	ENSFCAG00000029233	22 retrocopies	retro_fcat_1077, retro_fcat_1079, retro_fcat_1164, retro_fcat_1247, retro_fcat_1351, retro_fcat_1433, retro_fcat_1476, retro_fcat_1503, retro_fcat_1537, retro_fcat_1646, retro_fcat_1647, retro_fcat_1724, retro_fcat_174, retro_fcat_1849, retro_fcat_1899, retro_fcat_2006, retro_fcat_312, retro_fcat_486, retro_fcat_646, retro_fcat_696, retro_fcat_957, retro_fcat_967,
Homo sapiens	ENSG00000008988	26 retrocopies	retro_hsap_1062, retro_hsap_1078, retro_hsap_1164, retro_hsap_1247, retro_hsap_1383, retro_hsap_1497, retro_hsap_197, retro_hsap_2111, retro_hsap_2223, retro_hsap_2308, retro_hsap_2329, retro_hsap_2527, retro_hsap_2739, retro_hsap_3219, retro_hsap_3225, retro_hsap_3272, retro_hsap_3921, retro_hsap_393, retro_hsap_3974, retro_hsap_4045, retro_hsap_4099, retro_hsap_416, retro_hsap_4185, retro_hsap_4271, retro_hsap_870, retro_hsap_899,
Gorilla gorilla	ENSGGOG00000001837	21 retrocopies	retro_ggor_1074, retro_ggor_1149, retro_ggor_1581, retro_ggor_1640, retro_ggor_1751, retro_ggor_1768, retro_ggor_1908, retro_ggor_2193, retro_ggor_2227, retro_ggor_2639, retro_ggor_2712, retro_ggor_2751, retro_ggor_2809, retro_ggor_2857, retro_ggor_410, retro_ggor_707, retro_ggor_727, retro_ggor_838, retro_ggor_851, retro_ggor_909, retro_ggor_977,
Macropus eugenii	ENSMEUG00000014171	21 retrocopies	retro_meug_100, retro_meug_1015, retro_meug_1058, retro_meug_1170, retro_meug_1313, retro_meug_1614, retro_meug_1702, retro_meug_1761, retro_meug_1777, retro_meug_1831, retro_meug_1911, retro_meug_1951, retro_meug_2065, retro_meug_2110, retro_meug_2187, retro_meug_659, retro_meug_710, retro_meug_723, retro_meug_818, retro_meug_892, retro_meug_928,
Monodelphis domestica	ENSMODG00000009114	6 retrocopies	retro_mdom_1701, retro_mdom_1735, retro_mdom_1738, retro_mdom_1814, retro_mdom_1817, retro_mdom_1943,
Mustela putorius furo	ENSMPUG00000010452	15 retrocopies	retro_mputfur_1094, retro_mputfur_1188, retro_mputfur_1313, retro_mputfur_1366, retro_mputfur_1374, retro_mputfur_1432, retro_mputfur_238, retro_mputfur_249, retro_mputfur_320, retro_mputfur_418, retro_mputfur_424, retro_mputfur_433, retro_mputfur_620, retro_mputfur_77, retro_mputfur_819,
Mus musculus	ENSMUSG00000028234	7 retrocopies	retro_mmus_1442, retro_mmus_2796, retro_mmus_3138, retro_mmus_3159, retro_mmus_3321, retro_mmus_3627, retro_mmus_3718,
Nomascus leucogenys	ENSNLEG00000001214	19 retrocopies	retro_nleu_1013, retro_nleu_1343, retro_nleu_1447, retro_nleu_1566, retro_nleu_1794, retro_nleu_1798, retro_nleu_1805, retro_nleu_1818, retro_nleu_2059, retro_nleu_2159, retro_nleu_2654, retro_nleu_2659, retro_nleu_2750, retro_nleu_2786, retro_nleu_2819, retro_nleu_2843, retro_nleu_3066, retro_nleu_382, retro_nleu_41,
Oryctolagus cuniculus	ENSOCUG00000003068	17 retrocopies	retro_ocun_1006, retro_ocun_1076, retro_ocun_1218, retro_ocun_1438, retro_ocun_1467, retro_ocun_1526, retro_ocun_1585, retro_ocun_1586, retro_ocun_1609, retro_ocun_286, retro_ocun_299, retro_ocun_332, retro_ocun_682, retro_ocun_707, retro_ocun_783, retro_ocun_827, retro_ocun_948,
Otolemur garnettii	ENSOGAG00000007760	10 retrocopies	retro_ogar_1337, retro_ogar_1759, retro_ogar_177, retro_ogar_1927, retro_ogar_2203, retro_ogar_2286, retro_ogar_2576, retro_ogar_309, retro_ogar_310, retro_ogar_900,
Ochotona princeps	ENSOPRG00000011042	11 retrocopies	retro_opri_1022, retro_opri_1024, retro_opri_1156, retro_opri_1206, retro_opri_164, retro_opri_402, retro_opri_41, retro_opri_53, retro_opri_592, retro_opri_906, retro_opri_980,
Procavia capensis	ENSPCAG00000004300	3 retrocopies	retro_pcap_244, retro_pcap_427, retro_pcap_438,
Pongo abelii	ENSPPYG00000018600	30 retrocopies	retro_pabe_1038, retro_pabe_1148, retro_pabe_1248, retro_pabe_1508, retro_pabe_1860, retro_pabe_1981, retro_pabe_1992, retro_pabe_2176, retro_pabe_2180, retro_pabe_2667, retro_pabe_2674, retro_pabe_2692, retro_pabe_2708, retro_pabe_2815, retro_pabe_2950, retro_pabe_306, retro_pabe_319, retro_pabe_3193, retro_pabe_3317, retro_pabe_3356, retro_pabe_3424, retro_pabe_3485, retro_pabe_422, retro_pabe_440, retro_pabe_681, retro_pabe_776 , retro_pabe_885, retro_pabe_897, retro_pabe_902, retro_pabe_968,
Pan troglodytes	ENSPTRG00000020264	27 retrocopies	retro_ptro_1016, retro_ptro_1472, retro_ptro_1548, retro_ptro_1632, retro_ptro_1684, retro_ptro_1702, retro_ptro_176, retro_ptro_1853, retro_ptro_2169, retro_ptro_2177, retro_ptro_2213, retro_ptro_2665, retro_ptro_2699, retro_ptro_2739, retro_ptro_2780, retro_ptro_2839, retro_ptro_2897, retro_ptro_2946, retro_ptro_303, retro_ptro_318, retro_ptro_605, retro_ptro_620, retro_ptro_723, retro_ptro_732, retro_ptro_797, retro_ptro_858, retro_ptro_949,
Rattus norvegicus	ENSRNOG00000008555	7 retrocopies	retro_rnor_142, retro_rnor_155, retro_rnor_192, retro_rnor_288, retro_rnor_381, retro_rnor_401, retro_rnor_58,
Sarcophilus harrisii	ENSSHAG00000011200	10 retrocopies	retro_shar_135, retro_shar_228, retro_shar_418, retro_shar_436, retro_shar_441, retro_shar_443, retro_shar_450, retro_shar_504, retro_shar_544, retro_shar_785,
Sus scrofa	ENSSSCG00000006249	12 retrocopies	retro_sscr_1123, retro_sscr_30, retro_sscr_567, retro_sscr_575, retro_sscr_577, retro_sscr_585, retro_sscr_611, retro_sscr_646, retro_sscr_691, retro_sscr_708, retro_sscr_724, retro_sscr_838,