RetrogeneDB ID: retro_ggor_1251

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 16:2988970..2989308(-)
• Located in intron of: ENSGGOG00000015312

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: EIF1
• Ensembl ID: ENSGGOG00000027201
• Aliases: None
• Description: None

Sequence

>retro_ggor_1251
ATGTCCACTGTCCAGAATCTCCACTCTTCCACCCCTTTGCTGATTTAAGTAAGAGTGATGACCTGCTCCCTGCAGGCACT
GAGGAATACATCCATGCAAGAATTTAACAGACAAATGACAGGAAAACCCTTAGTACTGTCTAAGCGATCACTAAGGATTA
CAATAAAAAGCAACTAGTGAAGGCATTTAAGAGGAAATTTACCTGCAATGGGACGGTAATTGAGCATCCAGAATATGGAG
AAGTCATTCAGCTACAGGGTGACCAGCGCAAGAACATACGCCAGTTCCTTGTAGAGGTGGGACTGGCTAAGGACGATCAG
CTGATGGTTCAAGGGTTT

Alignment

ORF - retro_ggor_1251 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.95 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 2
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MSAIQNLHS-FDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFAC
          MS..QNLHS.F.PFAD.SK.DDLLPAGTE.YIH.RI.Q.N.RKTL.TV..I..DY.KK.LVKAFK.KF.C
Retrocopy MSTVQNLHS<FHPFADLSKSDDLLPAGTEEYIHARI*QTNDRKTLSTV*AITKDYNKKQLVKAFKRKFTC

Parental  NGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQLKVHGF
          NGTVIEHPEYGEVIQLQGDQRKNI.QFLVE.GLAKDDQL.V.GF
Retrocopy NGTVIEHPEYGEVIQLQGDQRKNIRQFLVEVGLAKDDQLMVQGF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	186.59 RPM
SRP007412_cerebellum	0.00 RPM	217.44 RPM
SRP007412_heart	0.00 RPM	123.30 RPM
SRP007412_kidney	0.00 RPM	324.00 RPM
SRP007412_liver	0.00 RPM	286.99 RPM
SRP007412_testis	0.00 RPM	324.16 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1251 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1251 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 83 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005620	9 retrocopies	retro_amel_1335, retro_amel_335, retro_amel_567, retro_amel_575, retro_amel_587, retro_amel_666, retro_amel_782, retro_amel_798, retro_amel_823,
Canis familiaris	ENSCAFG00000029584	4 retrocopies	retro_cfam_1465, retro_cfam_1479, retro_cfam_359, retro_cfam_655,
Callithrix jacchus	ENSCJAG00000012120	6 retrocopies	retro_cjac_1237, retro_cjac_2089, retro_cjac_346, retro_cjac_3815, retro_cjac_600, retro_cjac_84,
Cavia porcellus	ENSCPOG00000014350	3 retrocopies	retro_cpor_42, retro_cpor_613, retro_cpor_643,
Dasypus novemcinctus	ENSDNOG00000007856	11 retrocopies	retro_dnov_1098, retro_dnov_1110, retro_dnov_1368, retro_dnov_148, retro_dnov_1516, retro_dnov_1668, retro_dnov_1807, retro_dnov_2062, retro_dnov_2209, retro_dnov_402, retro_dnov_421,
Dipodomys ordii	ENSDORG00000013853	4 retrocopies	retro_dord_349, retro_dord_350, retro_dord_663, retro_dord_753,
Homo sapiens	ENSG00000173812	2 retrocopies	retro_hsap_1659, retro_hsap_271,
Gorilla gorilla	ENSGGOG00000027201	2 retrocopies	retro_ggor_1251 , retro_ggor_318,
Macropus eugenii	ENSMEUG00000015360	6 retrocopies	retro_meug_1513, retro_meug_1635, retro_meug_2189, retro_meug_315, retro_meug_749, retro_meug_821,
Myotis lucifugus	ENSMLUG00000005077	3 retrocopies	retro_mluc_233, retro_mluc_305, retro_mluc_330,
Otolemur garnettii	ENSOGAG00000031577	6 retrocopies	retro_ogar_1349, retro_ogar_1701, retro_ogar_1940, retro_ogar_2645, retro_ogar_2899, retro_ogar_856,
Pongo abelii	ENSPPYG00000029667	1 retrocopy	retro_pabe_127,
Rattus norvegicus	ENSRNOG00000033765	15 retrocopies	retro_rnor_1088, retro_rnor_1347, retro_rnor_1518, retro_rnor_1744, retro_rnor_1971, retro_rnor_2067, retro_rnor_2171, retro_rnor_2203, retro_rnor_2532, retro_rnor_2548, retro_rnor_2579, retro_rnor_45, retro_rnor_532, retro_rnor_571, retro_rnor_65,
Sorex araneus	ENSSARG00000006287	1 retrocopy	retro_sara_36,
Sarcophilus harrisii	ENSSHAG00000005729	1 retrocopy	retro_shar_42,
Sus scrofa	ENSSSCG00000017430	6 retrocopies	retro_sscr_1114, retro_sscr_1126, retro_sscr_1192, retro_sscr_394, retro_sscr_402, retro_sscr_922,
Tursiops truncatus	ENSTTRG00000017135	3 retrocopies	retro_ttru_1664, retro_ttru_224, retro_ttru_315,