RetrogeneDB ID: retro_mmul_2480

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: X:22344172..22344393(+)
• Located in intron of: ENSMMUG00000012819

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MMU.2197
• Ensembl ID: ENSMMUG00000031372
• Aliases: None
• Description: small nuclear ribonucleoprotein E [Source:RefSeq peptide;Acc:NP_001253704]

Sequence

>retro_mmul_2480
CTTACCTTCATCTTCAGATACTTGCAAAATAGATCTCGGATTCAGGTATGACTCTATGAGCAAGTGAATATGCTGATAGA
GGGCCGTATCATTGGTTTTGATGAGTCTGTGAACCTCATATCAGATGATGCAGAAGAGATTCATTGTGAAACAAAGCCAA
GAAAACCCCTGGGTCAGATCGTGCTAAAGGAGATCATATTCTGCCACAAAATGTCTCTAAC

Alignment

ORF - retro_mmul_2480 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 72.37 %
• Parental protein coverage: 81.52 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  INLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIML-KGDNITL
          ...IFRYLQNRSRIQV.LYEQVNM.IEG.IIGFDE..NL..DDAEEIH..TK.RK.LG.I.L.KGD.I.L
Retrocopy LTFIFRYLQNRSRIQV*LYEQVNMLIEGRIIGFDESVNLISDDAEEIHCETKPRKPLGQIVL<KGDHI-L

Parental  LQSVSN
          .Q.VSN
Retrocopy PQNVSN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	9.97 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	10.55 RPM
SRP007412_cerebellum	0.00 RPM	15.30 RPM
SRP007412_heart	0.00 RPM	10.83 RPM
SRP007412_kidney	0.00 RPM	13.15 RPM
SRP007412_liver	0.00 RPM	7.52 RPM
SRP007412_testis	0.00 RPM	4.49 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2480 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2480 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2480 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4660
Pan troglodytes	retro_ptro_3096
Gorilla gorilla	retro_ggor_2892
Pongo abelii	retro_pabe_3620

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 97 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000006735	1 retrocopy	retro_cjac_3163,
Dasypus novemcinctus	ENSDNOG00000004490	24 retrocopies	retro_dnov_1009, retro_dnov_1141, retro_dnov_122, retro_dnov_1223, retro_dnov_1312, retro_dnov_1314, retro_dnov_1362, retro_dnov_1438, retro_dnov_163, retro_dnov_191, retro_dnov_2398, retro_dnov_2671, retro_dnov_360, retro_dnov_414, retro_dnov_513, retro_dnov_579, retro_dnov_796, retro_dnov_828, retro_dnov_898, retro_dnov_900, retro_dnov_902, retro_dnov_93, retro_dnov_967, retro_dnov_983,
Echinops telfairi	ENSETEG00000014015	24 retrocopies	retro_etel_1136, retro_etel_1244, retro_etel_138, retro_etel_1443, retro_etel_1530, retro_etel_1636, retro_etel_1739, retro_etel_1781, retro_etel_1947, retro_etel_2143, retro_etel_234, retro_etel_258, retro_etel_310, retro_etel_377, retro_etel_466, retro_etel_546, retro_etel_56, retro_etel_579, retro_etel_581, retro_etel_582, retro_etel_76, retro_etel_776, retro_etel_799, retro_etel_80,
Gorilla gorilla	ENSGGOG00000000755	7 retrocopies	retro_ggor_1462, retro_ggor_1626, retro_ggor_1700, retro_ggor_2221, retro_ggor_228, retro_ggor_2892, retro_ggor_91,
Myotis lucifugus	ENSMLUG00000013244	8 retrocopies	retro_mluc_1639, retro_mluc_1650, retro_mluc_1994, retro_mluc_2045, retro_mluc_2088, retro_mluc_2326, retro_mluc_85, retro_mluc_919,
Macaca mulatta	ENSMMUG00000031372	8 retrocopies	retro_mmul_1039, retro_mmul_1258, retro_mmul_1576, retro_mmul_1790, retro_mmul_1820, retro_mmul_2054, retro_mmul_2480 , retro_mmul_427,
Mustela putorius furo	ENSMPUG00000011642	7 retrocopies	retro_mputfur_1078, retro_mputfur_1527, retro_mputfur_1634, retro_mputfur_53, retro_mputfur_638, retro_mputfur_729, retro_mputfur_949,
Pongo abelii	ENSPPYG00000000326	8 retrocopies	retro_pabe_1375, retro_pabe_20, retro_pabe_2023, retro_pabe_228, retro_pabe_3015, retro_pabe_3620, retro_pabe_56, retro_pabe_610,
Sorex araneus	ENSSARG00000003311	9 retrocopies	retro_sara_171, retro_sara_173, retro_sara_183, retro_sara_214, retro_sara_219, retro_sara_37, retro_sara_664, retro_sara_697, retro_sara_750,
Sarcophilus harrisii	ENSSHAG00000002978	1 retrocopy	retro_shar_357,