RetrogeneDB ID: retro_ggor_304

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:145910609..145911656(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000026797
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: RPL4
• Ensembl ID: ENSGGOG00000003695
• Aliases: None
• Description: None

Sequence

>retro_ggor_304
GCAGCTGGGCTGAGAGGAACATGGCTGTCTCCTCTCTCCACCATGGCATGTGCTCACCCACTGATATCGGTGTACTCCCA
AAAGAGGGAGTCATCTGGCAAAAATGTTACTATGCCTGCTGTATTCAAGGCTCCTATTTGACTGGATATTGTGAACTGTG
TTCACACCAACTTGCACAAAAACAACAGACAGCCCTACGTTGTCAGTGAATTAGCAGGTCGTCAGACCAGTGCTGAGTCT
TGGGGTACTGGCAGAGCTGTGGCTCACATTCCCAGAGTTCGAGGTGGTGGGACTCACCGTTCTGGCCAGGGTGCTTTTGG
AAACATGTGTCATGGAGGCCAAATGTTTGCACCAACCAAAACCTGGTGCCATTGGCATCACAGAGTGAACACAACCCAAA
AACGATATGCCATCTGTTCTGCCCTGGCTGCCTCAGCCTTACCAATGCTGGTCATGTCTAAAGATCATCATATTGAGGAA
GTTCCTGAACTTTCTTTGGTAGTTGAAGATAAAGTTGAAGGCTACAAGAAGATCAAGGAGGCTGTTTCGCTTCTTAAGAA
ACTTAAAGGCTGGAATGATATCAAAAAGGTCTATGCCTCTCAGCAAATGAGAGCTGGCAACAGCCAAATGAGAAACTGTC
ACTGTATCCAGTGCAGGGGCCCCTGCATCATCTATAATGAGGATAATGGTATCATCAAGGCCTTCAGAAACATCCCTGGA
ATTACTCTGCTTAATGTAAGCAAACTGAACATTTTGAAGCTTGCTCCTGGTGGGCATGTGGGACATTTCTGCATTTGGAC
CAAAAGTGCTTTCCAGAAGTTAGATGAATTGTATGGCACTTGGCATAAAGCTGCTTCCCTCAAGAGTAACTACCATCTTC
CCATGCACGAGATGTTCAATACAGATCTTAGCAGAATCTTGAAAAGCCCAGAGATCCAAAGAGCCCTTTGAGCACCATGC
AAGAAGATTCATTGCAGAGTCCTAAAGAAGAACCCACTGAAAAACCTGAGAATCATGTTGAAGCTAAACCCATACGCAAA
GACCATG

Alignment

ORF - retro_ggor_304 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86.93 %
• Parental protein coverage: 79.46 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  AAGLRGAWLSPLSAMACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSE
          AAGLRG.WLSPLS.MACA.PLISVYS.K.ESSGKNVT.PAVFKAPI..DIVN.VHTNL.KNNRQPY.VSE
Retrocopy AAGLRGTWLSPLSTMACAHPLISVYSQKRESSGKNVTMPAVFKAPI*LDIVNCVHTNLHKNNRQPYVVSE

Parental  LAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAICS
          LAG.QTSAESWGTGRAVA.IPRVRGGGTHRSGQGAFGNMC.GG.MFAPTKTW..WH.RVNTTQKRYAICS
Retrocopy LAGRQTSAESWGTGRAVAHIPRVRGGGTHRSGQGAFGNMCHGGQMFAPTKTWCHWHHRVNTTQKRYAICS

Parental  ALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKM
          ALAASALP.LVMSK.H.IEEVPEL.LVVEDKVEGYKK.KEAV.LLKKLK.WNDIKKVYASQ.MRAG...M
Retrocopy ALAASALPMLVMSKDHHIEEVPELSLVVEDKVEGYKKIKEAVSLLKKLKGWNDIKKVYASQQMRAGNSQM

Parental  RNRRRIQRRGPCIIYNEDNGIIKAFRNIPALKGITLLNVSKLNILKLAPGGHVGRFCIWTESAFRKLDEL
          RN...IQ.RGPCIIYNEDNGIIKAFRNIP...GITLLNVSKLNILKLAPGGHVG.FCIWT.SAF.KLDEL
Retrocopy RNCHCIQCRGPCIIYNEDNGIIKAFRNIP---GITLLNVSKLNILKLAPGGHVGHFCIWTKSAFQKLDEL

Parental  YGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQRALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAK
          YGTW.KAASLKSNY.LPMH.M.NTDLSRILKSPEIQRAL.AP.KKIH.RVLKKNPLKNLRIMLKLNPYAK
Retrocopy YGTWHKAASLKSNYHLPMHEMFNTDLSRILKSPEIQRAL*APCKKIHCRVLKKNPLKNLRIMLKLNPYAK

Parental  TM
          TM
Retrocopy TM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	264.47 RPM
SRP007412_cerebellum	0.00 RPM	268.50 RPM
SRP007412_heart	0.00 RPM	170.73 RPM
SRP007412_kidney	0.08 RPM	590.27 RPM
SRP007412_liver	0.00 RPM	436.29 RPM
SRP007412_testis	0.00 RPM	355.24 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_304 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_304 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Pan troglodytes	retro_ptro_214

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Parental genes homology:

Parental genes homology involve 31 parental genes, and 112 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005211	2 retrocopies	retro_btau_101, retro_btau_610,
Canis familiaris	ENSCAFG00000017309	1 retrocopy	retro_cfam_72,
Choloepus hoffmanni	ENSCHOG00000003008	6 retrocopies	retro_chof_1014, retro_chof_1496, retro_chof_2219, retro_chof_2616, retro_chof_455, retro_chof_476,
Callithrix jacchus	ENSCJAG00000007491	2 retrocopies	retro_cjac_251, retro_cjac_945,
Cavia porcellus	ENSCPOG00000003055	1 retrocopy	retro_cpor_370,
Dasypus novemcinctus	ENSDNOG00000006693	3 retrocopies	retro_dnov_1028, retro_dnov_1152, retro_dnov_1931,
Equus caballus	ENSECAG00000023179	1 retrocopy	retro_ecab_428,
Echinops telfairi	ENSETEG00000000337	3 retrocopies	retro_etel_1876, retro_etel_2195, retro_etel_226,
Felis catus	ENSFCAG00000012293	4 retrocopies	retro_fcat_1136, retro_fcat_189, retro_fcat_505, retro_fcat_567,
Homo sapiens	ENSG00000174444	5 retrocopies	retro_hsap_1306, retro_hsap_254, retro_hsap_2898, retro_hsap_4229, retro_hsap_471,
Gorilla gorilla	ENSGGOG00000003695	4 retrocopies	retro_ggor_1023, retro_ggor_2008, retro_ggor_2831, retro_ggor_304 ,
Loxodonta africana	ENSLAFG00000006494	3 retrocopies	retro_lafr_1076, retro_lafr_152, retro_lafr_960,
Microcebus murinus	ENSMICG00000004419	6 retrocopies	retro_mmur_1050, retro_mmur_1330, retro_mmur_440, retro_mmur_562, retro_mmur_830, retro_mmur_852,
Myotis lucifugus	ENSMLUG00000011809	2 retrocopies	retro_mluc_121, retro_mluc_198,
Macaca mulatta	ENSMMUG00000016844	2 retrocopies	retro_mmul_2160, retro_mmul_649,
Monodelphis domestica	ENSMODG00000009657	2 retrocopies	retro_mdom_656, retro_mdom_944,
Mustela putorius furo	ENSMPUG00000000337	3 retrocopies	retro_mputfur_1205, retro_mputfur_411, retro_mputfur_570,
Mus musculus	ENSMUSG00000032399	2 retrocopies	retro_mmus_2863, retro_mmus_495,
Nomascus leucogenys	ENSNLEG00000012938	4 retrocopies	retro_nleu_1041, retro_nleu_1062, retro_nleu_2385, retro_nleu_887,
Oryctolagus cuniculus	ENSOCUG00000008794	3 retrocopies	retro_ocun_1134, retro_ocun_630, retro_ocun_631,
Ochotona princeps	ENSOPRG00000007792	1 retrocopy	retro_opri_735,
Pongo abelii	ENSPPYG00000006578	1 retrocopy	retro_pabe_152,
Pan troglodytes	ENSPTRG00000007195	6 retrocopies	retro_ptro_1512, retro_ptro_1959, retro_ptro_214, retro_ptro_2873, retro_ptro_353, retro_ptro_897,
Pteropus vampyrus	ENSPVAG00000000068	18 retrocopies	retro_pvam_1222, retro_pvam_1342, retro_pvam_201, retro_pvam_202, retro_pvam_216, retro_pvam_236, retro_pvam_267, retro_pvam_399, retro_pvam_428, retro_pvam_430, retro_pvam_435, retro_pvam_466, retro_pvam_518, retro_pvam_736, retro_pvam_778, retro_pvam_819, retro_pvam_865, retro_pvam_955,
Rattus norvegicus	ENSRNOG00000009378	5 retrocopies	retro_rnor_1192, retro_rnor_1621, retro_rnor_2061, retro_rnor_2484, retro_rnor_949,
Sus scrofa	ENSSSCG00000004945	2 retrocopies	retro_sscr_138, retro_sscr_885,
Ictidomys tridecemlineatus	ENSSTOG00000009221	1 retrocopy	retro_itri_437,
Tupaia belangeri	ENSTBEG00000014392	9 retrocopies	retro_tbel_1701, retro_tbel_2186, retro_tbel_2649, retro_tbel_3302, retro_tbel_3577, retro_tbel_3624, retro_tbel_3938, retro_tbel_4340, retro_tbel_4402,
Tarsius syrichta	ENSTSYG00000005588	1 retrocopy	retro_tsyr_1144,
Tursiops truncatus	ENSTTRG00000010206	7 retrocopies	retro_ttru_1130, retro_ttru_1399, retro_ttru_1713, retro_ttru_177, retro_ttru_789, retro_ttru_817, retro_ttru_964,
Vicugna pacos	ENSVPAG00000006746	2 retrocopies	retro_vpac_143, retro_vpac_250,