RetrogeneDB ID: retro_lcha_11

Retrocopy location

• Organism: Coelacanth (Latimeria chalumnae)
• Coordinates: JH127681.1:84184..84571(-)
• Located in intron of: ENSLACG00000001341

Retrocopy information

• Ensembl ID: ENSLACG00000003456
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSLACG00000008132
• Aliases: None
• Description: None

Sequence

>retro_lcha_11
ATGCAGATCTTTGTGAAAACTCTGACTGGTAAAACCATCACCCTTGAGGTGGAGCCCAGTGATACAATTGAAAATGTTAA
GGCCAAGATTCAGGATAAGGAAGGAATCCCTCCTGACCAACAGCGTCTGATCTTTGCTGGCAAGCAGCTGGAAGATGGAC
GCACTCTGTCTGACTACAACATTCAGAAAGAGTCAACCCTGCATTTAGTGCTGCGTCTGCGTGGTGGTATCATCGAGCCC
TCTCTTCGCATGCTTGCTTGCAAATACAACTGTGACAAAATGATCTGCCACAAATGCTATGCTCGGCTCCATCCTCGTGC
TGTGAATTGCCGTAAGAAGAAGTGCGGACACACCAATAACCTGCGCCCAAAGAAGAAGCTGAAGTAA

Alignment

ORF - retro_lcha_11 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 99.22 %
• Parental protein coverage: 55.41 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLV
          MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLV
Retrocopy MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLV

Parental  LRLRGGIIEPSLRMLACKYNCDKMICRKCYARLHPRAVNCRKKKCGHTNNLRPKKKLK
          LRLRGGIIEPSLRMLACKYNCDKMIC.KCYARLHPRAVNCRKKKCGHTNNLRPKKKLK
Retrocopy LRLRGGIIEPSLRMLACKYNCDKMICHKCYARLHPRAVNCRKKKCGHTNNLRPKKKLK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
DRP000627_gill	0.57 RPM	337.82 RPM
DRP000627_kidney	0.99 RPM	521.81 RPM
DRP000627_pectoral_fin	2.96 RPM	534.73 RPM
DRP000627_pelvic_fin	0.93 RPM	444.17 RPM
DRP000627_pharynx	0.68 RPM	344.61 RPM
DRP000627_tail_muscle	0.60 RPM	227.13 RPM

ChIP-Seq

Latimeria chalumnae was not studied using ChIP-Seq data.

EST

Latimeria chalumnae was not studied using EST data.

TSS

Latimeria chalumnae was not studied using FANTOM5 data.

Lab

retro_lcha_11 was not experimentally validated.

Homology

Retrocopy orthology:

Latimeria chalumnae does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 30 parental genes, and 218 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000011356	10 retrocopies	retro_amel_1045, retro_amel_1416, retro_amel_1455, retro_amel_1759, retro_amel_1849, retro_amel_214, retro_amel_800, retro_amel_904, retro_amel_941, retro_amel_973,
Bos taurus	ENSBTAG00000007737	3 retrocopies	retro_btau_1059, retro_btau_1318, retro_btau_832,
Canis familiaris	ENSCAFG00000014723	8 retrocopies	retro_cfam_1671, retro_cfam_1725, retro_cfam_1879, retro_cfam_1933, retro_cfam_2205, retro_cfam_600, retro_cfam_654, retro_cfam_873,
Callithrix jacchus	ENSCJAG00000007470	22 retrocopies	retro_cjac_1363, retro_cjac_1388, retro_cjac_1426, retro_cjac_1485, retro_cjac_1521, retro_cjac_1561, retro_cjac_1731, retro_cjac_1743, retro_cjac_2002, retro_cjac_207, retro_cjac_2254, retro_cjac_2292, retro_cjac_2413, retro_cjac_2501, retro_cjac_2505, retro_cjac_2898, retro_cjac_3054, retro_cjac_658, retro_cjac_683, retro_cjac_883, retro_cjac_892, retro_cjac_898,
Cavia porcellus	ENSCPOG00000000351	3 retrocopies	retro_cpor_1454, retro_cpor_1471, retro_cpor_1502,
Equus caballus	ENSECAG00000020660	8 retrocopies	retro_ecab_1014, retro_ecab_107, retro_ecab_313, retro_ecab_641, retro_ecab_772, retro_ecab_835, retro_ecab_836, retro_ecab_857,
Echinops telfairi	ENSETEG00000003392	35 retrocopies	retro_etel_1121, retro_etel_113, retro_etel_1165, retro_etel_1229, retro_etel_1520, retro_etel_1521, retro_etel_1598, retro_etel_1618, retro_etel_1623, retro_etel_1644, retro_etel_1657, retro_etel_1707, retro_etel_1709, retro_etel_174, retro_etel_1756, retro_etel_1760, retro_etel_1785, retro_etel_1854, retro_etel_196, retro_etel_2027, retro_etel_2101, retro_etel_2123, retro_etel_2158, retro_etel_2166, retro_etel_268, retro_etel_376, retro_etel_386, retro_etel_406, retro_etel_660, retro_etel_690, retro_etel_70, retro_etel_755, retro_etel_807, retro_etel_843, retro_etel_859,
Felis catus	ENSFCAG00000009745	14 retrocopies	retro_fcat_1159, retro_fcat_1204, retro_fcat_1226, retro_fcat_1232, retro_fcat_1382, retro_fcat_1428, retro_fcat_1449, retro_fcat_1540, retro_fcat_1661, retro_fcat_86, retro_fcat_876, retro_fcat_909, retro_fcat_939, retro_fcat_989,
Homo sapiens	ENSG00000221983	2 retrocopies	retro_hsap_2622, retro_hsap_4004,
Gorilla gorilla	ENSGGOG00000004630	8 retrocopies	retro_ggor_1021, retro_ggor_1045, retro_ggor_1265, retro_ggor_1835, retro_ggor_2579, retro_ggor_2687, retro_ggor_2782, retro_ggor_905,
Latimeria chalumnae	ENSLACG00000008132	1 retrocopy	retro_lcha_11 ,
Macropus eugenii	ENSMEUG00000013159	5 retrocopies	retro_meug_1812, retro_meug_1868, retro_meug_441, retro_meug_513, retro_meug_750,
Microcebus murinus	ENSMICG00000017583	5 retrocopies	retro_mmur_143, retro_mmur_1486, retro_mmur_150, retro_mmur_633, retro_mmur_708,
Myotis lucifugus	ENSMLUG00000029594	5 retrocopies	retro_mluc_1995, retro_mluc_2057, retro_mluc_2203, retro_mluc_44, retro_mluc_829,
Macaca mulatta	ENSMMUG00000016085	7 retrocopies	retro_mmul_1184, retro_mmul_1580, retro_mmul_1625, retro_mmul_2183, retro_mmul_2311, retro_mmul_232, retro_mmul_896,
Monodelphis domestica	ENSMODG00000003499	1 retrocopy	retro_mdom_867,
Mustela putorius furo	ENSMPUG00000015527	8 retrocopies	retro_mputfur_1059, retro_mputfur_1119, retro_mputfur_1126, retro_mputfur_382, retro_mputfur_516, retro_mputfur_713, retro_mputfur_78, retro_mputfur_945,
Mus musculus	ENSMUSG00000090137	3 retrocopies	retro_mmus_101, retro_mmus_129, retro_mmus_31,
Otolemur garnettii	ENSOGAG00000028000	10 retrocopies	retro_ogar_1345, retro_ogar_1419, retro_ogar_1583, retro_ogar_1604, retro_ogar_1792, retro_ogar_2026, retro_ogar_2370, retro_ogar_2485, retro_ogar_2544, retro_ogar_3337,
Ochotona princeps	ENSOPRG00000004784	6 retrocopies	retro_opri_1016, retro_opri_144, retro_opri_219, retro_opri_458, retro_opri_644, retro_opri_787,
Pongo abelii	ENSPPYG00000009746	2 retrocopies	retro_pabe_111, retro_pabe_3291,
Pan troglodytes	ENSPTRG00000039223	8 retrocopies	retro_ptro_1142, retro_ptro_1767, retro_ptro_2607, retro_ptro_2718, retro_ptro_2815, retro_ptro_792, retro_ptro_895, retro_ptro_919,
Pteropus vampyrus	ENSPVAG00000024217	19 retrocopies	retro_pvam_1029, retro_pvam_1102, retro_pvam_1146, retro_pvam_1164, retro_pvam_1320, retro_pvam_1325, retro_pvam_1361, retro_pvam_1434, retro_pvam_1447, retro_pvam_211, retro_pvam_327, retro_pvam_517, retro_pvam_528, retro_pvam_600, retro_pvam_632, retro_pvam_655, retro_pvam_749, retro_pvam_987, retro_pvam_994,
Rattus norvegicus	ENSRNOG00000019974	7 retrocopies	retro_rnor_1125, retro_rnor_1458, retro_rnor_2115, retro_rnor_2472, retro_rnor_2487, retro_rnor_2901, retro_rnor_944,
Sorex araneus	ENSSARG00000000984	11 retrocopies	retro_sara_145, retro_sara_164, retro_sara_192, retro_sara_256, retro_sara_281, retro_sara_331, retro_sara_344, retro_sara_599, retro_sara_67, retro_sara_687, retro_sara_94,
Sarcophilus harrisii	ENSSHAG00000007075	3 retrocopies	retro_shar_405, retro_shar_434, retro_shar_703,
Sus scrofa	ENSSSCG00000013907	1 retrocopy	retro_sscr_988,
Ictidomys tridecemlineatus	ENSSTOG00000004678	1 retrocopy	retro_itri_49,
Tursiops truncatus	ENSTTRG00000021461	1 retrocopy	retro_ttru_1582,
Xiphophorus maculatus	ENSXMAG00000003911	1 retrocopy	retro_xmac_6,