RetrogeneDB ID: retro_btau_1442

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 5:102100650..102101142(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSBTAG00000003197
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: SRSF3
• Ensembl ID: ENSBTAG00000040006
• Aliases: SRSF3, SFRS3
• Description: Serine/arginine-rich splicing factor 3 [Source:UniProtKB/Swiss-Prot;Acc:Q3SZR8]

Sequence

>retro_btau_1442
ATGCATCGTGATTCCTGTCCATTGGACTGTAAAGTTTATGTAGGTAATCTTGGAAACAATGGTAACAAGACTGAATTGGA
ACGAGCTTTTGGCTATTATGGACCACTCCGAAGTGTGTGGGTTGCTAGAAACCCTCCCGGCTTTGCTTTTGTTGAATTTG
AAGATCCCCGAGACGCAGCTGATGCTGTCCGAGAGCTAGATGGGAGAACACTCTGTGGCTGCCGAGTAAGAGTGGAACTA
TCGAATGGTGAAAAGAGAAGTCGTAATCGTGGCCCACCTCCTTCTTGGGGTCGTCGCCCTCGAGATGATTATCGGAGGAG
GAGTCCTCCACCTCGACGCAGATCTCCAAGACGGAGAAGCTTCTCCCGCAGCCGGAGCAGGTCCCTTTCTAGCGATAGGA
GAAGAGAGAGATCACTGTCCCGGGAGAGAAATCACAAGCCGTCCCGATCTTTCTCTAGGTCTCGTAGCCGATCTAGGTCA
AATGAAAGGAAA

Alignment

ORF - retro_btau_1442 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 99.39 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT
          MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT
Retrocopy MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT

Parental  LCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLS
          LCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLS.DRRRERSLS
Retrocopy LCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSSDRRRERSLS

Parental  RERNHKPSRSFSRSRSRSRSNERK
          RERNHKPSRSFSRSRSRSRSNERK
Retrocopy RERNHKPSRSFSRSRSRSRSNERK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.22 RPM	57.68 RPM
ERP005899_muscle	0.32 RPM	60.92 RPM
SRP017611_brain	0.09 RPM	18.00 RPM
SRP017611_kidney	0.06 RPM	49.79 RPM
SRP017611_liver	0.08 RPM	21.14 RPM
SRP030211_testis	0.65 RPM	77.70 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1442 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1442 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1442 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 79 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000012792	1 retrocopy	retro_btau_837,
Bos taurus	ENSBTAG00000040006	5 retrocopies	retro_btau_1176, retro_btau_1442 , retro_btau_1445, retro_btau_1665, retro_btau_1813,
Callithrix jacchus	ENSCJAG00000016062	5 retrocopies	retro_cjac_1035, retro_cjac_1969, retro_cjac_2006, retro_cjac_620, retro_cjac_746,
Homo sapiens	ENSG00000112081	4 retrocopies	retro_hsap_2140, retro_hsap_2299, retro_hsap_2304, retro_hsap_757,
Loxodonta africana	ENSLAFG00000018193	2 retrocopies	retro_lafr_1219, retro_lafr_80,
Microcebus murinus	ENSMICG00000004674	5 retrocopies	retro_mmur_1090, retro_mmur_160, retro_mmur_287, retro_mmur_710, retro_mmur_916,
Myotis lucifugus	ENSMLUG00000010671	6 retrocopies	retro_mluc_1205, retro_mluc_1312, retro_mluc_1554, retro_mluc_2283, retro_mluc_278, retro_mluc_51,
Mustela putorius furo	ENSMPUG00000014215	1 retrocopy	retro_mputfur_613,
Mus musculus	ENSMUSG00000071172	9 retrocopies	retro_mmus_100, retro_mmus_1347, retro_mmus_1749, retro_mmus_2294, retro_mmus_2337, retro_mmus_2433, retro_mmus_2654, retro_mmus_2933, retro_mmus_3629,
Otolemur garnettii	ENSOGAG00000000502	6 retrocopies	retro_ogar_1850, retro_ogar_1959, retro_ogar_2131, retro_ogar_2783, retro_ogar_597, retro_ogar_803,
Ochotona princeps	ENSOPRG00000006006	3 retrocopies	retro_opri_1037, retro_opri_158, retro_opri_545,
Rattus norvegicus	ENSRNOG00000000520	11 retrocopies	retro_rnor_1010, retro_rnor_1283, retro_rnor_1321, retro_rnor_1339, retro_rnor_1647, retro_rnor_1697, retro_rnor_1889, retro_rnor_2424, retro_rnor_634, retro_rnor_728, retro_rnor_790,
Sus scrofa	ENSSSCG00000001564	1 retrocopy	retro_sscr_1038,
Ictidomys tridecemlineatus	ENSSTOG00000014280	5 retrocopies	retro_itri_123, retro_itri_502, retro_itri_664, retro_itri_857, retro_itri_901,
Tarsius syrichta	ENSTSYG00000013498	3 retrocopies	retro_tsyr_1867, retro_tsyr_2163, retro_tsyr_848,
Tursiops truncatus	ENSTTRG00000013447	11 retrocopies	retro_ttru_105, retro_ttru_1195, retro_ttru_1577, retro_ttru_1628, retro_ttru_1639, retro_ttru_1653, retro_ttru_1677, retro_ttru_1731, retro_ttru_1892, retro_ttru_610, retro_ttru_916,
Vicugna pacos	ENSVPAG00000005481	1 retrocopy	retro_vpac_541,