RetrogeneDB ID: retro_cjac_2718

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 6:47149110..47150081(+)
• Located in intron of: ENSCJAG00000007144

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: YBX1
• Ensembl ID: ENSCJAG00000003155
• Aliases: None
• Description: Y box binding protein 1 [Source:HGNC Symbol;Acc:8014]

Sequence

>retro_cjac_2718
GAGCCACAGCTGCCGCAGCCGGCCCCAGTCATCATCACCGGAACCATGAGCAGTGAGGGCAAGACCCAGCAGCCGCCGGC
CGCCCCCGCCCTCAGCGCCGCCAACACCCAGCATGGCACTACAGGCAGCGGCGCAGGGAGCGGTGGCCCGGGGACAAGAA
GGTTCATCGCTGGGAAGGTTTTGAGAACAGTAAAATGATTCAATGTAAGGAATGGATATGGTTTCATCAACAGGAATGAC
ACCAAGGAAGATGTATTTGTACACCAGACTGCCATAAAGAAGAATAACCCCAGGAATTACCTTCCCAGTGTAGGAGATGG
AGAGACTGTGGAGTTTGATGTTGTTGAAGGAGAAAAGCGTGCAGAGGCAGCAAATGTTACAGGTTCTGGTGGCGTTCCAG
TTCAAGGCAGTAAATATACAGCAGACTGTAACCATTATGGACGCTATACACATCGTAGGGGTCCTCCACACAATTACCAG
CAAAATTACCAGAATAGTGAGAGTGGGGAAAAGAACAACAGATCTGAGACTGCTCCCAAAGGCCAGGCCTGACAACGCTG
GCCCTACCGCAGGTGAAGTTTCCCACCTTACTACATGAGGAGACCCTATGGGCGTCGACCACAATATTCCAACCCTCCTG
TGCAGGGAGAAGTGATGGAGGGTGCTGACAACCGGGGTACAGGAGAACAAGGCAGACCAGTGAGGCAGAATATGTATTGG
GGATACAGACCATGATTCCGCAGGGGCCCTCCTTGCCAAAGACAGCCTAGAGAGGACGGCAATGAAGAAGATAAAGAAAA
GGAGATGAGACCCAAGGTCAGCATCCACCTCAACGTTGGTACCGCTGCAACTTCAATTACCAACGCAGACACCCAGAAAA
CTCTAAACAACAAGATGGCAAAGAGACAAAAGCAGCCGATCCACCAGCTGAGAATTCATCTGCTCTGGAGGCTGAGCAGG
GCGGGGCTGAG

Alignment

ORF - retro_cjac_2718 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.31 %
• Parental protein coverage: 98.46 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  ETQQPPAAPPAAPALSAADTK----PGTTGSGAGSGGPGCLTSAAPAGGD--KKFCATKVLGTVKWFNVR
          E.Q.P..AP...........K....P......A.....G...S.A..GG.....F.A.KVL.TVK.FNVR
Retrocopy EPQLPQPAPVIITGTMSSEGKTQQPPAAPALSAANTQHGTTGSGAGSGGPGTRRFIAGKVLRTVK*FNVR

Parental  NGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYA
          NGYGFINRNDTKEDVFVHQTAIKKNNPR.YL.SVGDGETVEFDVVEGEK.AEAANVTG.GGVPVQGSKY.
Retrocopy NGYGFINRNDTKEDVFVHQTAIKKNNPRNYLPSVGDGETVEFDVVEGEKRAEAANVTGSGGVPVQGSKYT

Parental  ADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGSESAPEGQAQQRRPYRRRRFPPYYMRRPYGRRPQYS
          AD.NHY.RY..RRGPP.NYQQNYQNSESGEKN..SE.AP.GQA.QR.PYRR..FPPYYMRRPYGRRPQYS
Retrocopy ADCNHYGRYTHRRGPPHNYQQNYQNSESGEKNNRSETAPKGQA*QRWPYRR*SFPPYYMRRPYGRRPQYS

Parental  NPPVQGEVMEGADNQGAGEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQ-GDETQGQQPPQ
          NPPVQGEVMEGADN.G.GEQGRPVRQNMY.GYRP.FRRGPP.QRQPR.....E......GDETQGQ.PPQ
Retrocopy NPPVQGEVMEGADNRGTGEQGRPVRQNMYWGYRP*FRRGPPCQRQPR-EDGNEEDKEK<GDETQGQHPPQ

Parental  RRYRRNFNYRRRRPENPKPQDGKETKAADPPAENSSAPEAEQGGAE
          R.YR.NFNY.RR.PEN.K.QDGKETKAADPPAENSSA.EAEQGGAE
Retrocopy RWYRCNFNYQRRHPENSKQQDGKETKAADPPAENSSALEAEQGGAE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.22 RPM	93.36 RPM
SRP051959_heart	0.23 RPM	196.68 RPM
SRP051959_kidney	0.33 RPM	120.78 RPM
SRP051959_liver	0.19 RPM	138.35 RPM
SRP051959_lung	0.44 RPM	118.83 RPM
SRP051959_lymph_node	0.37 RPM	96.23 RPM
SRP051959_skeletal_muscle	0.15 RPM	179.27 RPM
SRP051959_spleen	0.48 RPM	129.50 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_2718 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_2718 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_2718 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 126 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000000494	9 retrocopies	retro_amel_1280, retro_amel_1358, retro_amel_141, retro_amel_1486, retro_amel_215, retro_amel_418, retro_amel_625, retro_amel_837, retro_amel_909,
Canis familiaris	ENSCAFG00000002541	4 retrocopies	retro_cfam_1312, retro_cfam_2118, retro_cfam_758, retro_cfam_91,
Callithrix jacchus	ENSCJAG00000003155	6 retrocopies	retro_cjac_1261, retro_cjac_1701, retro_cjac_2718 , retro_cjac_3156, retro_cjac_4172, retro_cjac_817,
Callithrix jacchus	ENSCJAG00000016581	1 retrocopy	retro_cjac_1473,
Cavia porcellus	ENSCPOG00000010888	3 retrocopies	retro_cpor_654, retro_cpor_833, retro_cpor_905,
Felis catus	ENSFCAG00000022604	6 retrocopies	retro_fcat_145, retro_fcat_1554, retro_fcat_1956, retro_fcat_241, retro_fcat_503, retro_fcat_631,
Homo sapiens	ENSG00000065978	4 retrocopies	retro_hsap_1433, retro_hsap_3886, retro_hsap_4250, retro_hsap_4301,
Loxodonta africana	ENSLAFG00000007597	1 retrocopy	retro_lafr_804,
Microcebus murinus	ENSMICG00000014984	19 retrocopies	retro_mmur_1098, retro_mmur_1285, retro_mmur_1326, retro_mmur_1435, retro_mmur_1437, retro_mmur_1445, retro_mmur_1621, retro_mmur_199, retro_mmur_315, retro_mmur_413, retro_mmur_581, retro_mmur_640, retro_mmur_676, retro_mmur_679, retro_mmur_726, retro_mmur_837, retro_mmur_900, retro_mmur_919, retro_mmur_942,
Macaca mulatta	ENSMMUG00000013136	5 retrocopies	retro_mmul_1139, retro_mmul_1423, retro_mmul_2017, retro_mmul_423, retro_mmul_861,
Nomascus leucogenys	ENSNLEG00000012324	7 retrocopies	retro_nleu_1053, retro_nleu_1188, retro_nleu_1312, retro_nleu_1601, retro_nleu_1749, retro_nleu_1888, retro_nleu_270,
Oryctolagus cuniculus	ENSOCUG00000028047	2 retrocopies	retro_ocun_1519, retro_ocun_1953,
Otolemur garnettii	ENSOGAG00000006784	25 retrocopies	retro_ogar_1127, retro_ogar_1246, retro_ogar_1350, retro_ogar_1371, retro_ogar_1497, retro_ogar_2011, retro_ogar_2018, retro_ogar_2302, retro_ogar_2359, retro_ogar_2607, retro_ogar_2654, retro_ogar_3170, retro_ogar_3225, retro_ogar_324, retro_ogar_3303, retro_ogar_3316, retro_ogar_3317, retro_ogar_3366, retro_ogar_3416, retro_ogar_3474, retro_ogar_448, retro_ogar_572, retro_ogar_678, retro_ogar_690, retro_ogar_753,
Pongo abelii	ENSPPYG00000001466	7 retrocopies	retro_pabe_1216, retro_pabe_1320, retro_pabe_2054, retro_pabe_2292, retro_pabe_3167, retro_pabe_3388, retro_pabe_3502,
Pteropus vampyrus	ENSPVAG00000005504	7 retrocopies	retro_pvam_1255, retro_pvam_1348, retro_pvam_1391, retro_pvam_145, retro_pvam_405, retro_pvam_76, retro_pvam_971,
Sorex araneus	ENSSARG00000007896	1 retrocopy	retro_sara_559,
Tupaia belangeri	ENSTBEG00000015642	9 retrocopies	retro_tbel_1183, retro_tbel_1955, retro_tbel_2347, retro_tbel_2694, retro_tbel_2702, retro_tbel_2961, retro_tbel_3590, retro_tbel_4037, retro_tbel_4478,
Tarsius syrichta	ENSTSYG00000006915	6 retrocopies	retro_tsyr_1030, retro_tsyr_173, retro_tsyr_2037, retro_tsyr_610, retro_tsyr_840, retro_tsyr_996,
Tursiops truncatus	ENSTTRG00000001353	2 retrocopies	retro_ttru_461, retro_ttru_746,
Vicugna pacos	ENSVPAG00000000068	2 retrocopies	retro_vpac_235, retro_vpac_647,