RetrogeneDB ID: retro_ggor_89

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 7:141805635..141806016(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000026448
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: HINT1
• Ensembl ID: ENSGGOG00000011967
• Aliases: None
• Description: None

Sequence

>retro_ggor_89
ATGGCAGGTGAGATCGCCAAGGCTCAGGTCGCTCGGCCTGGTGGCAACACTGTCTTCGGGAAGATCATCTGCAAGGAAAT
CCCAGCCAAAATCATTTTTGAGGATGACCAGTGCCTTGCTTTCCATGACACTTCCCCTCAAGCACCAACACATTTTCTGT
TGATATCGAAAAAACATATATCCCAGATTTCTGCAGCAGAAGATGATGACGAAAGTCTTCTTGGACACTTAATGATTGTT
GGCAAGAAATGTGCTGCTGATTTGGGCCTGAATAAGGGTTATCAAATGGTGGTGAATAAAGGTTCAGATGGTGGACAGTC
TGTCTATCAAGTTCATCTCCATGTTCTTGGAGGTTGGCAGATGCATTGGCCTCCTGGTTAA

Alignment

ORF - retro_ggor_89 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.68 %
• Parental protein coverage: 77.3 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDD
          MA.EIAKAQVARPGG.T.FGKII.KEIPAKIIFEDD.CLAFHD.SPQAPTHFL.I.KKHISQIS.AEDDD
Retrocopy MAGEIAKAQVARPGGNTVFGKIICKEIPAKIIFEDDQCLAFHDTSPQAPTHFLLISKKHISQISAAEDDD

Parental  ESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
          ESLLGHLMIVGKKCAADLGLNKGY.MVVN.GSDGGQSVY.VHLHVLGG.QMHWPPG
Retrocopy ESLLGHLMIVGKKCAADLGLNKGYQMVVNKGSDGGQSVYQVHLHVLGGWQMHWPPG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	97.01 RPM
SRP007412_cerebellum	0.04 RPM	55.20 RPM
SRP007412_heart	0.00 RPM	41.84 RPM
SRP007412_kidney	0.04 RPM	180.61 RPM
SRP007412_liver	0.08 RPM	160.98 RPM
SRP007412_testis	0.21 RPM	90.65 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_89 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_89 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3913
Pan troglodytes	retro_ptro_2661
Macaca mulatta	retro_mmul_759

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Parental genes homology:

Parental genes homology involve 27 parental genes, and 60 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000017774	4 retrocopies	retro_amel_1426, retro_amel_1657, retro_amel_460, retro_amel_511,
Bos taurus	ENSBTAG00000010959	5 retrocopies	retro_btau_1036, retro_btau_1149, retro_btau_1782, retro_btau_926, retro_btau_978,
Canis familiaris	ENSCAFG00000032152	1 retrocopy	retro_cfam_473,
Callithrix jacchus	ENSCJAG00000014398	3 retrocopies	retro_cjac_134, retro_cjac_142, retro_cjac_87,
Equus caballus	ENSECAG00000023180	3 retrocopies	retro_ecab_264, retro_ecab_356, retro_ecab_550,
Erinaceus europaeus	ENSEEUG00000008175	1 retrocopy	retro_eeur_582,
Echinops telfairi	ENSETEG00000010127	1 retrocopy	retro_etel_1,
Homo sapiens	ENSG00000169567	1 retrocopy	retro_hsap_3913,
Gorilla gorilla	ENSGGOG00000011265	1 retrocopy	retro_ggor_1823,
Gorilla gorilla	ENSGGOG00000011967	1 retrocopy	retro_ggor_89 ,
Macropus eugenii	ENSMEUG00000005368	2 retrocopies	retro_meug_1001, retro_meug_848,
Myotis lucifugus	ENSMLUG00000001091	2 retrocopies	retro_mluc_1388, retro_mluc_2100,
Macaca mulatta	ENSMMUG00000009985	2 retrocopies	retro_mmul_1896, retro_mmul_759,
Monodelphis domestica	ENSMODG00000028727	3 retrocopies	retro_mdom_102, retro_mdom_1741, retro_mdom_286,
Mustela putorius furo	ENSMPUG00000011639	4 retrocopies	retro_mputfur_1337, retro_mputfur_1376, retro_mputfur_45, retro_mputfur_93,
Mus musculus	ENSMUSG00000020267	1 retrocopy	retro_mmus_718,
Nomascus leucogenys	ENSNLEG00000012431	1 retrocopy	retro_nleu_2155,
Oryctolagus cuniculus	ENSOCUG00000006607	5 retrocopies	retro_ocun_1374, retro_ocun_214, retro_ocun_643, retro_ocun_821, retro_ocun_968,
Otolemur garnettii	ENSOGAG00000008850	2 retrocopies	retro_ogar_1028, retro_ogar_1599,
Procavia capensis	ENSPCAG00000004737	1 retrocopy	retro_pcap_407,
Pongo abelii	ENSPPYG00000015747	2 retrocopies	retro_pabe_3189, retro_pabe_909,
Pan troglodytes	ENSPTRG00000017206	1 retrocopy	retro_ptro_2661,
Rattus norvegicus	ENSRNOG00000000622	1 retrocopy	retro_rnor_98,
Sarcophilus harrisii	ENSSHAG00000005834	2 retrocopies	retro_shar_113, retro_shar_301,
Sus scrofa	ENSSSCG00000014264	2 retrocopies	retro_sscr_371, retro_sscr_894,
Ictidomys tridecemlineatus	ENSSTOG00000027920	4 retrocopies	retro_itri_1129, retro_itri_114, retro_itri_177, retro_itri_260,
Tursiops truncatus	ENSTTRG00000008653	4 retrocopies	retro_ttru_1364, retro_ttru_1660, retro_ttru_217, retro_ttru_349,