RetrogeneDB ID: retro_pabe_537

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 10:65990756..65991155(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ATP5G1
• Ensembl ID: ENSPPYG00000008909
• Aliases: None
• Description: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) [Source:HGNC Symbol;Acc:841]

Sequence

>retro_pabe_537
ACCACCGGGGCACTACTCATTTCTCCAGCTCTGATCCGCTATTGTACCAGGGGTCTAATCGGGCCTGTGTCTGCCTCCTT
CTTGAATAGCCCAGAGAATTCATCTAAACAGCTTCCTACAGCAACTCCCTACTCCAGGGGCCAGACAGAATTCCAGACCA
GTGTTGTCTCTGGGGACATTGACACAGCAGCCAAGTTGATTGGTGCTGGGGCAGCCACAGTTGGTGTGGCTGGTTCAGGG
GCTGACATTGGAACTGTGTTTGGCAGCTAGATCATTGGCTATGCCAGGAACCCATCTCTCAAGCAGCAGCTCTTCTCCTA
TGCCATTCTGGGCTTTGCCTTGTCTGAGGCCACGGGGCTCTTCTATTTGATGGTTGCCTTTCTCATCCTCTTTGCCATG

Alignment

ORF - retro_pabe_537 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.84 %
• Parental protein coverage: 98.53 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  TAGALFISPALIRCCTRGLIRPVSASFLNSPVNSSKQPSYSNFPLQVARREFQTSVVSRDIDTAAKFIGA
          T.GAL.ISPALIR.CTRGLI.PVSASFLNSP.NSSKQ......P......EFQTSVVS.DIDTAAK.IGA
Retrocopy TTGALLISPALIRYCTRGLIGPVSASFLNSPENSSKQLPTAT-PYSRGQTEFQTSVVSGDIDTAAKLIGA

Parental  GAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
          GAATVGVAGSGA.IGTVFGS.IIGYARNPSLKQQLFSYAILGFALSEA.GLF.LMVAFLILFAM
Retrocopy GAATVGVAGSGADIGTVFGS*IIGYARNPSLKQQLFSYAILGFALSEATGLFYLMVAFLILFAM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	42.19 RPM
SRP007412_cerebellum	0.00 RPM	20.31 RPM
SRP007412_heart	0.00 RPM	72.13 RPM
SRP007412_kidney	0.00 RPM	62.55 RPM
SRP007412_liver	0.03 RPM	32.56 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_537 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_537 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_537 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_686
Pan troglodytes	retro_ptro_491
Gorilla gorilla	retro_ggor_589

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 88 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000006341	1 retrocopy	retro_acar_9,
Canis familiaris	ENSCAFG00000016880	5 retrocopies	retro_cfam_1583, retro_cfam_1621, retro_cfam_1882, retro_cfam_336, retro_cfam_647,
Callithrix jacchus	ENSCJAG00000007352	7 retrocopies	retro_cjac_1190, retro_cjac_1549, retro_cjac_161, retro_cjac_1878, retro_cjac_289, retro_cjac_4060, retro_cjac_679,
Cavia porcellus	ENSCPOG00000009017	2 retrocopies	retro_cpor_43, retro_cpor_550,
Equus caballus	ENSECAG00000019908	1 retrocopy	retro_ecab_463,
Felis catus	ENSFCAG00000002344	2 retrocopies	retro_fcat_1165, retro_fcat_1346,
Homo sapiens	ENSG00000159199	8 retrocopies	retro_hsap_1054, retro_hsap_1234, retro_hsap_1397, retro_hsap_1464, retro_hsap_2844, retro_hsap_2882, retro_hsap_597, retro_hsap_686,
Gorilla gorilla	ENSGGOG00000001626	8 retrocopies	retro_ggor_1083, retro_ggor_1125, retro_ggor_1388, retro_ggor_1998, retro_ggor_528, retro_ggor_589, retro_ggor_831, retro_ggor_967,
Loxodonta africana	ENSLAFG00000004537	2 retrocopies	retro_lafr_341, retro_lafr_522,
Macropus eugenii	ENSMEUG00000005744	2 retrocopies	retro_meug_1650, retro_meug_1973,
Myotis lucifugus	ENSMLUG00000011738	4 retrocopies	retro_mluc_1276, retro_mluc_1508, retro_mluc_1885, retro_mluc_2498,
Macaca mulatta	ENSMMUG00000013395	1 retrocopy	retro_mmul_173,
Mustela putorius furo	ENSMPUG00000015341	3 retrocopies	retro_mputfur_1575, retro_mputfur_479, retro_mputfur_497,
Nomascus leucogenys	ENSNLEG00000002718	6 retrocopies	retro_nleu_1082, retro_nleu_1475, retro_nleu_2074, retro_nleu_2219, retro_nleu_623, retro_nleu_777,
Pongo abelii	ENSPPYG00000004586	7 retrocopies	retro_pabe_1211, retro_pabe_1212, retro_pabe_2073, retro_pabe_2255, retro_pabe_236, retro_pabe_3088, retro_pabe_3741,
Pongo abelii	ENSPPYG00000008909	9 retrocopies	retro_pabe_1027, retro_pabe_1156, retro_pabe_1576, retro_pabe_1607, retro_pabe_2353, retro_pabe_2387, retro_pabe_537 , retro_pabe_593, retro_pabe_879,
Pan troglodytes	ENSPTRG00000009364	8 retrocopies	retro_ptro_1273, retro_ptro_1926, retro_ptro_1950, retro_ptro_440, retro_ptro_491, retro_ptro_718, retro_ptro_847, retro_ptro_960,
Rattus norvegicus	ENSRNOG00000007235	5 retrocopies	retro_rnor_1342, retro_rnor_2240, retro_rnor_529, retro_rnor_64, retro_rnor_880,
Ictidomys tridecemlineatus	ENSSTOG00000013404	2 retrocopies	retro_itri_1604, retro_itri_560,
Tupaia belangeri	ENSTBEG00000003575	5 retrocopies	retro_tbel_2765, retro_tbel_3270, retro_tbel_3540, retro_tbel_387, retro_tbel_4002,