RetrogeneDB ID: retro_ggor_2508

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 7:26506074..26506490(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPL23
• Ensembl ID: ENSGGOG00000025082
• Aliases: None
• Description: None

Sequence

>retro_ggor_2508
ATGTCGAAGCAAGGATGTGGTGAGTCCTCTGGTGCAAAATTCTGGATTTCCTTGGGTCTTCTGGTAGGATCCCTGATCAA
CAATGCTGACAATACAGGAGCCAAAAATCTGTATATCATCTCCATGAAGAGGATCAGGGACGGCTGAACAGACTTCCCTG
CCAGTGTGGGTGACATGGGGATGGCCACAGTCAAGAAAGACAAACCAGAGCTCAGAAAAAAGGTACATCCAGCAGTGGTC
ACTTGACAACAAAAGTCATATGGAGAAAAGACGGTGTGTTTCTTTATTTTGAAGGTAATGCAGGGGTCATAATAAAAAAC
AAAGACGAGATGAAAAGTTCTGCCATTACAGGACCAGTAGCAAAGGAGTGTGCAGACTTGTGGCCCCGGATTGCGTTCAA
TACTGGCAGCATTGCA

Alignment

ORF - retro_ggor_2508 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.72 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIK-GRLNRL-PAAGVGDMVMATVKKG
          MSK.G.G.SSGAKF.ISLGL.VG..IN.ADNTGAKNLYIIS.K.I..GRLNRL.PA..VGDM.MATVKK.
Retrocopy MSKQGCGESSGAKFWISLGLLVGSLINNADNTGAKNLYIISMKRIR<GRLNRL>PAS-VGDMGMATVKKD

Parental  KPELRKKVHPAVVIRQRKSYR-RKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAG
          KPELRKKVHPAVV..Q.KSY..RKDGVFLYFE.NAGVI..NK.EMK.SAITGPVAKECADLWPRIA.N.G
Retrocopy KPELRKKVHPAVVT*QQKSYG<RKDGVFLYFEGNAGVIIKNKDEMKSSAITGPVAKECADLWPRIAFNTG

Parental  SIA
          SIA
Retrocopy SIA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	88.67 RPM
SRP007412_cerebellum	0.04 RPM	83.41 RPM
SRP007412_heart	0.00 RPM	74.11 RPM
SRP007412_kidney	0.00 RPM	374.17 RPM
SRP007412_liver	0.00 RPM	246.11 RPM
SRP007412_testis	0.31 RPM	176.43 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2508 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2508 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_3710
Pan troglodytes	retro_ptro_2513
Pongo abelii	retro_pabe_3145

---

Parental genes homology:

Parental genes homology involve 13 parental genes, and 81 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004268	6 retrocopies	retro_amel_1791, retro_amel_226, retro_amel_308, retro_amel_880, retro_amel_918, retro_amel_990,
Callithrix jacchus	ENSCJAG00000008311	9 retrocopies	retro_cjac_1129, retro_cjac_1483, retro_cjac_2283, retro_cjac_2598, retro_cjac_2639, retro_cjac_2772, retro_cjac_2885, retro_cjac_3128, retro_cjac_3831,
Gorilla gorilla	ENSGGOG00000025082	9 retrocopies	retro_ggor_1574, retro_ggor_1744, retro_ggor_1746, retro_ggor_2416, retro_ggor_2508 , retro_ggor_256, retro_ggor_2710, retro_ggor_2757, retro_ggor_504,
Latimeria chalumnae	ENSLACG00000004430	1 retrocopy	retro_lcha_16,
Macaca mulatta	ENSMMUG00000004502	9 retrocopies	retro_mmul_1598, retro_mmul_1705, retro_mmul_1955, retro_mmul_2366, retro_mmul_2391, retro_mmul_384, retro_mmul_928, retro_mmul_930, retro_mmul_935,
Monodelphis domestica	ENSMODG00000012634	3 retrocopies	retro_mdom_1949, retro_mdom_527, retro_mdom_916,
Mustela putorius furo	ENSMPUG00000015075	2 retrocopies	retro_mputfur_1138, retro_mputfur_1324,
Nomascus leucogenys	ENSNLEG00000000642	7 retrocopies	retro_nleu_1506, retro_nleu_181, retro_nleu_2056, retro_nleu_2337, retro_nleu_2988, retro_nleu_574, retro_nleu_8,
Oryctolagus cuniculus	ENSOCUG00000013915	6 retrocopies	retro_ocun_1027, retro_ocun_1196, retro_ocun_1270, retro_ocun_1919, retro_ocun_251, retro_ocun_482,
Otolemur garnettii	ENSOGAG00000012445	7 retrocopies	retro_ogar_1050, retro_ogar_1645, retro_ogar_1695, retro_ogar_2250, retro_ogar_277, retro_ogar_3145, retro_ogar_539,
Ochotona princeps	ENSOPRG00000001957	10 retrocopies	retro_opri_1079, retro_opri_1216, retro_opri_137, retro_opri_14, retro_opri_178, retro_opri_202, retro_opri_224, retro_opri_481, retro_opri_639, retro_opri_684,
Pteropus vampyrus	ENSPVAG00000002277	2 retrocopies	retro_pvam_488, retro_pvam_890,
Rattus norvegicus	ENSRNOG00000004107	10 retrocopies	retro_rnor_1195, retro_rnor_1539, retro_rnor_1622, retro_rnor_2445, retro_rnor_2483, retro_rnor_2688, retro_rnor_2981, retro_rnor_347, retro_rnor_498, retro_rnor_941,