RetrogeneDB ID: retro_btau_558

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 14:39523636..39524174(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSBTAG00000005559
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: BT.62437
• Ensembl ID: ENSBTAG00000002949
• Aliases: None
• Description: chromobox protein homolog 1 [Source:RefSeq peptide;Acc:NP_001193344]

Sequence

>retro_btau_558
AACAAGAAGAAAGTGGAGGAGGTGCTAGAAGAAGAGGAAGAAGAATATGTAGTGGGAAAGTTTTAGACCATTGAGTGGTA
AAGGGCAAAGTGGAGTATCTCCTAAAGTGGAAGGGGTTCTCAGATGAGGATAACACATGGGAACCAGAAGAGAAACTGGA
TTGCCCTGACCTCATTGCTGAGTTTCTGCAGTCACAGAAAACAGCATACGAGACAGATAAATCAGAGGCAGGCAAGCGCA
AAGCTGATTCTGATTCGGAAGATAAGGGGGAGGAGAGCAAACCAAAGAAGAAGAAAGAAGAGTCAGAAAAGCCACGAGGC
TTTGCCCAGGGTTTGGAACCAGAGCAGATTATTGGAGCTAGAGACTCCAGTGGAGAACTCATGTTCCTGATGACATGAAG
AACTCTGATGAGGCTGACCTGGTCCCTGCCAAGGAACCCAATGTCAAGTGCCCACAGGTTGTCATATCCTTCTATGAGGA
AAGGCTGACATGGCATTCTTACCCCTCAGAGGATGATGACAAAAAAGATGACAGGAAT

Alignment

ORF - retro_btau_558 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.76 %
• Parental protein coverage: 97.3 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  NKKKVEEVLEEEEEEYVVEK-VLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTA
          NKKKVEEVLEEEEEEYVV.K.VLD..VVKGKVEYLLKWKGFSDEDNTWEPEE.LDCPDLIAEFLQSQKTA
Retrocopy NKKKVEEVLEEEEEEYVVGK<VLDH*VVKGKVEYLLKWKGFSDEDNTWEPEEKLDCPDLIAEFLQSQKTA

Parental  HETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLM-KWKNSDE
          .ETDKSE.GKRKADSDSEDKGEESKPKKKKEESEKPRGFA.GLEPE.IIGA.DSSGELMFLM...KNSDE
Retrocopy YETDKSEAGKRKADSDSEDKGEESKPKKKKEESEKPRGFAQGLEPEQIIGARDSSGELMFLM<DMKNSDE

Parental  ADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
          ADLVPAKE.NVKCPQVVISFYEERLTWHSYPSEDDDKKDD.N
Retrocopy ADLVPAKEPNVKCPQVVISFYEERLTWHSYPSEDDDKKDDRN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.00 RPM	0.72 RPM
ERP005899_muscle	0.00 RPM	6.18 RPM
SRP017611_brain	0.00 RPM	8.72 RPM
SRP017611_kidney	0.00 RPM	9.01 RPM
SRP017611_liver	0.00 RPM	2.87 RPM
SRP030211_testis	0.02 RPM	20.91 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_558 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_558 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_558 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 51 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004890	2 retrocopies	retro_amel_1228, retro_amel_54,
Bos taurus	ENSBTAG00000002949	9 retrocopies	retro_btau_1121, retro_btau_1394, retro_btau_148, retro_btau_1583, retro_btau_1615, retro_btau_550, retro_btau_558 , retro_btau_714, retro_btau_807,
Callithrix jacchus	ENSCJAG00000007532	2 retrocopies	retro_cjac_191, retro_cjac_51,
Dipodomys ordii	ENSDORG00000000716	2 retrocopies	retro_dord_594, retro_dord_709,
Erinaceus europaeus	ENSEEUG00000004874	3 retrocopies	retro_eeur_121, retro_eeur_228, retro_eeur_396,
Echinops telfairi	ENSETEG00000000203	7 retrocopies	retro_etel_1083, retro_etel_1572, retro_etel_1577, retro_etel_1611, retro_etel_2165, retro_etel_382, retro_etel_932,
Felis catus	ENSFCAG00000006056	1 retrocopy	retro_fcat_514,
Myotis lucifugus	ENSMLUG00000005030	2 retrocopies	retro_mluc_1000, retro_mluc_1533,
Mus musculus	ENSMUSG00000018666	1 retrocopy	retro_mmus_3108,
Oryctolagus cuniculus	ENSOCUG00000008021	3 retrocopies	retro_ocun_177, retro_ocun_442, retro_ocun_55,
Otolemur garnettii	ENSOGAG00000005658	9 retrocopies	retro_ogar_1087, retro_ogar_1092, retro_ogar_1322, retro_ogar_2056, retro_ogar_2396, retro_ogar_2443, retro_ogar_2840, retro_ogar_2880, retro_ogar_368,
Ochotona princeps	ENSOPRG00000003699	1 retrocopy	retro_opri_552,
Pongo abelii	ENSPPYG00000008891	1 retrocopy	retro_pabe_78,
Rattus norvegicus	ENSRNOG00000008689	2 retrocopies	retro_rnor_2388, retro_rnor_2841,
Sarcophilus harrisii	ENSSHAG00000008192	1 retrocopy	retro_shar_76,
Ictidomys tridecemlineatus	ENSSTOG00000023986	3 retrocopies	retro_itri_1282, retro_itri_1599, retro_itri_1867,
Tarsius syrichta	ENSTSYG00000004769	2 retrocopies	retro_tsyr_1672, retro_tsyr_467,