RetrogeneDB ID: retro_chof_1267

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_24140:9453..10329(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NANOG
• Ensembl ID: ENSCHOG00000000972
• Aliases: None
• Description: Nanog homeobox [Source:HGNC Symbol;Acc:20857]

Sequence

>retro_chof_1267
ATGAGCGTGGATCTAGCTTCTCCCCAAAGCCTGCCTTGCCCTGAAACAGATGATTCTAGCGAGTCTTCACCAATGCCTGA
GATTTATGAGGCTGAAGAAAATTAAGCATCCTTGCAACTGTCGTCTGCTGAGGTGCACCAGTCAGAGACAGTCTCTCCTC
TTCCTTCCTCTGTGGATCTGCTTACTCAGGATAGCCCCTACTCTTCCAGTCCCAAAGTAAAACTACCCGCGCCTGGAGGG
AAGAGCATAGGGAAGAAGGAAGATGAGGGCCAGGTCAAGAAACAGAAGATCAGAACTGTGTTCTCTCAGACCCAGCTATG
TATACTCAATGATAGATTTCAAAGACAGAAATGCCTCAGCCTCCAGAAGATGCAAGAACTTTCCAACATTCTGAACCTCA
GCTACAAACAGGTTAAGACCTGGTTCCAGAACCGGAGAATGAAATGTAAGAAGTGGCAGAAAAACACCAACTGGTCAAAG
AGTAGCAACAGTGTGATCCAGGGCTTAGCACCTACAGAATACCCAGAACTCTACTCTTCCTATCCCCAAGGGAGCTTGGT
GAACACTTATAGTAACTTTCCCATGTGGAGCAACCAGACCTGGAACAGTCCAATTTGGAGCAGCCATTCCTGAAACAGCC
AACCCTGGTACACCCAAGCCTGGAATAATAACCCAGTCTGGAACAATCAGTTCCAGAACAGTGAAGAGGAATCCCAGCAA
ACCCAGGTCCAATTCCAGCAAAATTCTCCTGCCAGTGAGTTGGAGGCCACCTCGGGAAGTTCTGGGGAAAGCCATAATGT
AATAGAGCAAACTGCTAAATATTTAAGAACCCTACACACCATGGATTTATTCCCAAATTACTTCATGAATACCCAG

Alignment

ORF - retro_chof_1267 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 86.05 %
• Parental protein coverage: 99.32 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSVDLASTQSLPCPETDNSRESSPMPEIYEAEKNYASLQMSSAEVHQPETVSPLPSSVDLLIQDSPDSST
          MSVDLAS.QSLPCPETD.S.ESSPMPEIYEAE.N.ASLQ.SSAEVHQ.ETVSPLPSSVDLL.QDSP.SS.
Retrocopy MSVDLASPQSLPCPETDDSSESSPMPEIYEAEEN*ASLQLSSAEVHQSETVSPLPSSVDLLTQDSPYSS-

Parental  SPKVKLPMSGGKSAGRKEDEGQVKKQKIRTVFSQTQLCILNDRFQKQKYLSLQQMQELSNILNLSYKQVK
          SPKVKLP..GGKS.G.KEDEGQVKKQKIRTVFSQTQLCILNDRFQ.QK.LSLQ.MQELSNILNLSYKQVK
Retrocopy SPKVKLPAPGGKSIGKKEDEGQVKKQKIRTVFSQTQLCILNDRFQRQKCLSLQKMQELSNILNLSYKQVK

Parental  TWFQNQRMKCKKWQKNTNWSKNGNSVIQKGSAPTEFPGLYSSYPQGCLANTSGNFPMWSNQTWNSPIWSS
          TWFQN.RMKCKKWQKNTNWSK..NSVIQ.G.APTE.P.LYSSYPQG.L.NT..NFPMWSNQTWNSPIWSS
Retrocopy TWFQNRRMKCKKWQKNTNWSKSSNSVIQ-GLAPTEYPELYSSYPQGSLVNTYSNFPMWSNQTWNSPIWSS

Parental  HSWSSQHWYTQAWNNNPVWNNQFQNSGEESLQLQVQFQQNSPASDLEATLGSAGENHNVIEQAAKYFSTL
          HS..SQ.WYTQAWNNNPVWNNQFQNS.EES.Q.QVQFQQNSPAS.LEAT.GS.GE.HNVIEQ.AKY..TL
Retrocopy HS*NSQPWYTQAWNNNPVWNNQFQNSEEESQQTQVQFQQNSPASELEATSGSSGESHNVIEQTAKYLRTL

Parental  HTMDLFPNYFMNTQ
          HTMDLFPNYFMNTQ
Retrocopy HTMDLFPNYFMNTQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1267 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 23 parental genes, and 67 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000017064	1 retrocopy	retro_amel_354,
Canis familiaris	ENSCAFG00000013914	1 retrocopy	retro_cfam_724,
Choloepus hoffmanni	ENSCHOG00000000972	4 retrocopies	retro_chof_1267 , retro_chof_264, retro_chof_794, retro_chof_987,
Callithrix jacchus	ENSCJAG00000018999	8 retrocopies	retro_cjac_1732, retro_cjac_2234, retro_cjac_2441, retro_cjac_402, retro_cjac_4153, retro_cjac_4177, retro_cjac_880, retro_cjac_989,
Cavia porcellus	ENSCPOG00000002621	1 retrocopy	retro_cpor_1132,
Echinops telfairi	ENSETEG00000004648	8 retrocopies	retro_etel_1155, retro_etel_1334, retro_etel_134, retro_etel_1434, retro_etel_1935, retro_etel_630, retro_etel_818, retro_etel_963,
Felis catus	ENSFCAG00000001621	1 retrocopy	retro_fcat_932,
Homo sapiens	ENSG00000111704	5 retrocopies	retro_hsap_1455, retro_hsap_1549, retro_hsap_3713, retro_hsap_4814, retro_hsap_722,
Gorilla gorilla	ENSGGOG00000028196	4 retrocopies	retro_ggor_1812, retro_ggor_2510, retro_ggor_3000, retro_ggor_608,
Macropus eugenii	ENSMEUG00000009949	2 retrocopies	retro_meug_266, retro_meug_940,
Microcebus murinus	ENSMICG00000002228	1 retrocopy	retro_mmur_575,
Myotis lucifugus	ENSMLUG00000029325	2 retrocopies	retro_mluc_1562, retro_mluc_2054,
Myotis lucifugus	ENSMLUG00000030580	1 retrocopy	retro_mluc_169,
Macaca mulatta	ENSMMUG00000032158	4 retrocopies	retro_mmul_1901, retro_mmul_2466, retro_mmul_964, retro_mmul_979,
Monodelphis domestica	ENSMODG00000017979	2 retrocopies	retro_mdom_1293, retro_mdom_1938,
Mustela putorius furo	ENSMPUG00000016731	5 retrocopies	retro_mputfur_1140, retro_mputfur_1553, retro_mputfur_261, retro_mputfur_553, retro_mputfur_691,
Nomascus leucogenys	ENSNLEG00000005359	3 retrocopies	retro_nleu_1086, retro_nleu_2189, retro_nleu_2340,
Oryctolagus cuniculus	ENSOCUG00000013783	1 retrocopy	retro_ocun_971,
Otolemur garnettii	ENSOGAG00000026339	1 retrocopy	retro_ogar_568,
Procavia capensis	ENSPCAG00000015460	2 retrocopies	retro_pcap_143, retro_pcap_429,
Pongo abelii	ENSPPYG00000004233	5 retrocopies	retro_pabe_2157, retro_pabe_3142, retro_pabe_3440, retro_pabe_3742, retro_pabe_623,
Pan troglodytes	ENSPTRG00000029807	4 retrocopies	retro_ptro_1746, retro_ptro_2514, retro_ptro_3203, retro_ptro_990,
Pteropus vampyrus	ENSPVAG00000006989	1 retrocopy	retro_pvam_1251,