RetrogeneDB ID: retro_pabe_2632

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 5:44160802..44161185(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SLMO2
• Ensembl ID: ENSPPYG00000011182
• Aliases: None
• Description: slowmo homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:15892]

Sequence

>retro_pabe_2632
AAACCTCTTACTGGTGCAACAAAACCCAAAACATACGTACTAGAATATTCTGTAGTTAATCCTGTAGAGAAAACAATGGA
ATTTAAATCTACTAATATTTCACTTACAAATATGATTTCAGTAGGTGAGAGATTTATACACAAACCACATCATCGGGACC
CCCCAAAAGGCTATTTTGACTCAAGAAGCCATAATCGCTGAAGAGAGGTAGCCTCAGCAGTTACCTTGAAGGACTGATGG
CAAGAACGATACCTTCAAATGCTAATAAAGGCCGAGAAGCACTGAAATGAGTCATACATAAATTACATGTTAAGACTGAA
GAATAGACAGCTTCCGCCAAGAGGAAGCATATAAGAACTTCGATGGCAGCGGCTGCAGCAGCA

Alignment

ORF - retro_pabe_2632 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 63.57 %
• Parental protein coverage: 73.41 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  KSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQD-PEKTVLTQEAIITVKG
          K.L.GA...KTYV.E.SVV.PVEKTME.KSTNIS.TNM.SV.ER.I.KPH..D.P.K...........K.
Retrocopy KPLTGATKPKTYVLEYSVVNPVEKTMEFKSTNISLTNMISVGERFIHKPHHRD<PPKRLF*LKKP*SLKR

Parental  VSLSSYLEGLMASTISSNASKGREAMEWVIHKLNAEIEELTASA-RGTIRTPMAAAAFA
          .SLSSYLEGLMA.TI.SNA.KGREA...VIHKL....EE.TASA.R..IRT.MAAAA.A
Retrocopy GSLSSYLEGLMARTIPSNANKGREALK*VIHKLHVKTEE*TASAKRKHIRTSMAAAAAA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	3.48 RPM
SRP007412_cerebellum	0.00 RPM	9.24 RPM
SRP007412_heart	0.00 RPM	5.51 RPM
SRP007412_kidney	0.00 RPM	5.37 RPM
SRP007412_liver	0.00 RPM	5.20 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_2632 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_2632 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_2632 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 26 parental genes, and 101 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000004402	3 retrocopies	retro_btau_1006, retro_btau_1346, retro_btau_996,
Canis familiaris	ENSCAFG00000012220	1 retrocopy	retro_cfam_1293,
Callithrix jacchus	ENSCJAG00000018905	4 retrocopies	retro_cjac_1286, retro_cjac_2921, retro_cjac_3171, retro_cjac_3236,
Cavia porcellus	ENSCPOG00000012397	4 retrocopies	retro_cpor_1285, retro_cpor_1412, retro_cpor_456, retro_cpor_468,
Dasypus novemcinctus	ENSDNOG00000014548	3 retrocopies	retro_dnov_1402, retro_dnov_2032, retro_dnov_2311,
Equus caballus	ENSECAG00000000513	1 retrocopy	retro_ecab_409,
Erinaceus europaeus	ENSEEUG00000003697	4 retrocopies	retro_eeur_244, retro_eeur_34, retro_eeur_389, retro_eeur_406,
Felis catus	ENSFCAG00000031431	1 retrocopy	retro_fcat_1499,
Homo sapiens	ENSG00000101166	6 retrocopies	retro_hsap_310, retro_hsap_3166, retro_hsap_3167, retro_hsap_3311, retro_hsap_3783, retro_hsap_4227,
Gorilla gorilla	ENSGGOG00000004803	5 retrocopies	retro_ggor_1349, retro_ggor_1350, retro_ggor_2544, retro_ggor_2545, retro_ggor_2830,
Microcebus murinus	ENSMICG00000014902	12 retrocopies	retro_mmur_101, retro_mmur_1111, retro_mmur_1143, retro_mmur_1299, retro_mmur_1304, retro_mmur_1318, retro_mmur_1391, retro_mmur_1400, retro_mmur_1604, retro_mmur_512, retro_mmur_659, retro_mmur_912,
Myotis lucifugus	ENSMLUG00000014907	2 retrocopies	retro_mluc_1887, retro_mluc_845,
Macaca mulatta	ENSMMUG00000007560	4 retrocopies	retro_mmul_1155, retro_mmul_1644, retro_mmul_2123, retro_mmul_539,
Monodelphis domestica	ENSMODG00000016608	5 retrocopies	retro_mdom_1596, retro_mdom_1619, retro_mdom_1620, retro_mdom_1655, retro_mdom_405,
Mustela putorius furo	ENSMPUG00000007075	1 retrocopy	retro_mputfur_1586,
Nomascus leucogenys	ENSNLEG00000009579	3 retrocopies	retro_nleu_1118, retro_nleu_2497, retro_nleu_2498,
Oryctolagus cuniculus	ENSOCUG00000005621	8 retrocopies	retro_ocun_1944, retro_ocun_1954, retro_ocun_455, retro_ocun_486, retro_ocun_549, retro_ocun_619, retro_ocun_775, retro_ocun_926,
Otolemur garnettii	ENSOGAG00000013382	10 retrocopies	retro_ogar_1037, retro_ogar_1650, retro_ogar_2233, retro_ogar_2972, retro_ogar_3009, retro_ogar_3120, retro_ogar_3281, retro_ogar_3378, retro_ogar_3389, retro_ogar_3392,
Pongo abelii	ENSPPYG00000011182	7 retrocopies	retro_pabe_1462, retro_pabe_2631, retro_pabe_2632 , retro_pabe_2731, retro_pabe_3089, retro_pabe_3411, retro_pabe_371,
Pan troglodytes	ENSPTRG00000013682	5 retrocopies	retro_ptro_2160, retro_ptro_2273, retro_ptro_251, retro_ptro_252, retro_ptro_2564,
Pteropus vampyrus	ENSPVAG00000005226	2 retrocopies	retro_pvam_1075, retro_pvam_1445,
Sus scrofa	ENSSSCG00000007525	3 retrocopies	retro_sscr_161, retro_sscr_258, retro_sscr_959,
Tupaia belangeri	ENSTBEG00000000493	1 retrocopy	retro_tbel_1407,
Tarsius syrichta	ENSTSYG00000012533	2 retrocopies	retro_tsyr_2061, retro_tsyr_250,
Tursiops truncatus	ENSTTRG00000008417	2 retrocopies	retro_ttru_621, retro_ttru_818,
Vicugna pacos	ENSVPAG00000001044	2 retrocopies	retro_vpac_224, retro_vpac_359,