RetrogeneDB ID: retro_pvam_320

Retrocopy location

• Organism: Megabat (Pteropus vampyrus)
• Coordinates: GeneScaffold_253:399159..399959(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: LDHB
• Ensembl ID: ENSPVAG00000002462
• Aliases: None
• Description: lactate dehydrogenase B [Source:HGNC Symbol;Acc:6541]

Sequence

>retro_pvam_320
AAGGAAGAACAAAGCCCCCAGAATAAGATTATAGTCATTGGGGTTAGTGCTATTGGCATGGCCTATGTCATCAGTATCTT
ACTGAAAGACTTGGCAGATGAACTTGCCTCTGGTGGTGTCATGGAAGACAAATTGAATGGAGAGGTGATAGATCTCCAAA
ATGGCAGCCTTTTCCTTAGAACACCAAAAACTGTCTCTGGCAAAGACTATAAAGTGACTGCCAGCTCCAAGCTGGTTATT
ACCACCGCGAGGTACATCAACAAAAGGGAGAAAGCTGTCTTAATTTGGTCCAGCGTAAGGTGAATATCTTTAAATTCATC
ATTCCCAATGTTGTAAAATGCAGCCCTAACTGCAAATTGCTTATTGTTTCCAATTTAGTGGATATCTTGACCTATGTGGC
TTGGAAGATAAGCAGCTTTCCCCAAAGCCATGTTACCAGCAGTCGTTGCAATCTGGATTCATCCCAGTTCTGTTACTTCA
TAGGGGAAAGGCTAGGAATTCACCCATTAGGCTGTCATAGGTAGGTCTTTTGGGAGCATGGAGACTCTAATGTGCTTTGT
CTGGAGTGGAGTTAATGGTGCTGGTGTCTCCCTAAAGAATCTGCACCCTGATTTAGGCACTGATGCAGATGAGGAATGGT
GGAAATAAGTTCACAAACAGGTAGTTGACAGTGCTTATGAGTGATCAAATGGAGAGGTTACACGTCCTGGGCCATTGAAC
TATCTGTGGGAAACTTGGCGGAAAATATAATGAAGAACCTTGAGTGAATGCATTGAGTTTCCACCATGATTAAGGGACTC

Alignment

ORF - retro_pvam_320 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 61.11 %
• Parental protein coverage: 80.06 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  EEAAVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDY
          .E...P.NKI.V.GV...GMA..ISIL.K.LADELA...V.EDKL.GE..DLQ.GSLFL.TPK.V..KDY
Retrocopy KEEQSPQNKIIVIGVSAIGMAYVISILLKDLADELASGGVMEDKLNGEVIDLQNGSLFLRTPKTVSGKDY

Parental  SVTANSKVVVVTAG-VRQQEGESRLNLVQRNVNVFKFIIPQIIKYSPDCIIIVVSNPVDILTYVTWKLSG
          .VTA.SK.V..TA..V.QQ.GES.LNLVQR.VN.FKFIIP...K.SP.C....VSN.VDILTYV.WK.S.
Retrocopy KVTASSKLVITTAR<VHQQKGESCLNLVQRKVNIFKFIIPNVVKCSPNCKLLIVSNLVDILTYVAWKISS

Parental  LPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVA-VWSGVNVA-VSLQELNPEMGTD
          .P...V..S.CNLDS..F.Y...E.LGIHP..CH.....EHGDS.V..VWSGVN.A.VSL..L.P..GTD
Retrocopy FPQSHVTSSRCNLDSSQFCYFIGERLGIHPLGCHR*VFWEHGDSNVL>VWSGVNGAGVSLKNLHPDLGTD

Parental  NDSENWKEVHKMVV-SAYE-VIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGM
          .D.E.WK.VHK.VV.SAYE.VIK..GYT.WAI.LSV..L.E...KNL...H.VSTM.KG.
Retrocopy ADEEWWK*VHKQVVDSAYE<VIKWRGYTSWAIELSVGNLAENIMKNLE*MH*VSTMIKGL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Pteropus vampyrus was not studied using RNA-Seq expression data.

ChIP-Seq

Pteropus vampyrus was not studied using ChIP-Seq data.

EST

Pteropus vampyrus was not studied using EST data.

TSS

Pteropus vampyrus was not studied using FANTOM5 data.

Lab

retro_pvam_320 was not experimentally validated.

Homology

Retrocopy orthology:

Pteropus vampyrus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 56 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016175	4 retrocopies	retro_amel_1316, retro_amel_814, retro_amel_882, retro_amel_977,
Canis familiaris	ENSCAFG00000012195	9 retrocopies	retro_cfam_1068, retro_cfam_111, retro_cfam_1674, retro_cfam_17, retro_cfam_1700, retro_cfam_174, retro_cfam_1836, retro_cfam_701, retro_cfam_93,
Cavia porcellus	ENSCPOG00000007138	1 retrocopy	retro_cpor_762,
Dasypus novemcinctus	ENSDNOG00000013620	4 retrocopies	retro_dnov_1161, retro_dnov_1511, retro_dnov_1570, retro_dnov_529,
Felis catus	ENSFCAG00000012639	1 retrocopy	retro_fcat_462,
Gorilla gorilla	ENSGGOG00000015758	1 retrocopy	retro_ggor_3033,
Loxodonta africana	ENSLAFG00000000972	2 retrocopies	retro_lafr_197, retro_lafr_315,
Macropus eugenii	ENSMEUG00000004825	1 retrocopy	retro_meug_311,
Microcebus murinus	ENSMICG00000017183	2 retrocopies	retro_mmur_275, retro_mmur_300,
Myotis lucifugus	ENSMLUG00000012155	1 retrocopy	retro_mluc_202,
Macaca mulatta	ENSMMUG00000002679	4 retrocopies	retro_mmul_212, retro_mmul_303, retro_mmul_308, retro_mmul_315,
Monodelphis domestica	ENSMODG00000017786	1 retrocopy	retro_mdom_1484,
Mustela putorius furo	ENSMPUG00000000172	5 retrocopies	retro_mputfur_1300, retro_mputfur_1561, retro_mputfur_492, retro_mputfur_539, retro_mputfur_549,
Mus musculus	ENSMUSG00000030246	4 retrocopies	retro_mmus_1817, retro_mmus_2035, retro_mmus_2509, retro_mmus_335,
Otolemur garnettii	ENSOGAG00000004763	9 retrocopies	retro_ogar_1469, retro_ogar_2093, retro_ogar_2344, retro_ogar_2459, retro_ogar_3288, retro_ogar_3342, retro_ogar_3383, retro_ogar_689, retro_ogar_721,
Pteropus vampyrus	ENSPVAG00000002462	3 retrocopies	retro_pvam_1487, retro_pvam_320 , retro_pvam_673,
Rattus norvegicus	ENSRNOG00000013000	3 retrocopies	retro_rnor_2697, retro_rnor_2749, retro_rnor_2834,
Sus scrofa	ENSSSCG00000000576	1 retrocopy	retro_sscr_37,