RetrogeneDB ID: retro_ocun_579

Retrocopy location

• Organism: Rabbit (Oryctolagus cuniculus)
• Coordinates: 12:106453961..106454576(-)
• Located in intron of: ENSOCUG00000003157

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PHB
• Ensembl ID: ENSOCUG00000007209
• Aliases: None
• Description: prohibitin [Source:HGNC Symbol;Acc:8912]

Sequence

>retro_ocun_579
ATGGCTGCCAAAGTGTTTGAGTCCATTGGCAAGTCCGGCCTAGCCATAAGTGTTGCTGAAGATGTGGGGAACTTTGCCTC
ATGGAATGTGGATGCTGGGCACAGAGCTGTCATCTCTGACCAGTTCTGTGGCGTGCAGGACATGGTGGTGGGGAGAAGGA
ACTCATTTCCTCATCCCGTGGGTGCAGAAATCAATTATCTTTGCCGCTCGTGCCCGTGGAATGTGTGGGCCACCACCGGC
AGCAAACAATTACAGAACGTCGACTTCACGCTGCGCAGCCTCTTCTGGCAGGTGGCCAGCCAGCTTCCGACCGTCTTCAG
CAGCAGCCGAGAGCGCTATGATAAACTCGTCCTGCTGTCTATCACCTTGGAGCTCCTCAAGTCCGCGATGGCGCACTTTG
ACGCCGGGAAGCTCATCACCCAGAGAGAGAGGGTATCCAGGCAAGTGCGCGATGACCTGACAGAGCGCGTGGCCACCTTT
GGCCTCATCCTGGATGGGGTGTCCTTGACACATCTGACCTTCGGGAGGGAGTTCACAGAAGCAGTGGAAGCCAAACCAGT
GGCTTGGCAGGAAGCAGAGAGGGCCAGGTTTGTGGTGAAGGCAGAGCAGCATAAG

Alignment

ORF - retro_ocun_579 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.01 %
• Parental protein coverage: 76.1 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAAKVFESIGKFGLALAVAGGVVNSALYNVDAGHRAVIFDRFRGVQDMVVGEGTHFLIPWVQKPIIFDCR
          MAAKVFESIGK.GLA..VA..V.N.A..NVDAGHRAVI.D.F.GVQDMVVG....F..P.V...I...CR
Retrocopy MAAKVFESIGKSGLAISVAEDVGNFASWNVDAGHRAVISDQFCGVQDMVVGRRNSFPHP-VGAEINYLCR

Parental  SRPRNVPVITGSKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELI
          S.P.NV...TGSK.LQNV..TLR.LF..VASQLP..F.S..E.YD..VL.SIT.E.LKS..A.FDAG.LI
Retrocopy SCPWNVWATTGSKQLQNVDFTLRSLFWQVASQLPTVFSSSRERYDKLVLLSITLELLKSAMAHFDAGKLI

Parental  TQRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQK
          TQRE.VSRQV.DDLTER.ATFGLILD.VSLTHLTFG.EFTEAVEAK.VA.QEAERARFVV.KAEQ.K
Retrocopy TQRERVSRQVRDDLTERVATFGLILDGVSLTHLTFGREFTEAVEAKPVAWQEAERARFVV-KAEQHK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	44.43 RPM
SRP017611_kidney	0.00 RPM	116.86 RPM
SRP017611_liver	0.00 RPM	30.83 RPM

ChIP-Seq

Oryctolagus cuniculus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ocun_579 retrocopy.

TSS

Oryctolagus cuniculus was not studied using FANTOM5 data.

Lab

retro_ocun_579 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ocun_579 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 120 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000004797	1 retrocopy	retro_acar_49,
Choloepus hoffmanni	ENSCHOG00000007588	2 retrocopies	retro_chof_1159, retro_chof_2193,
Callithrix jacchus	ENSCJAG00000007174	22 retrocopies	retro_cjac_1048, retro_cjac_1403, retro_cjac_1683, retro_cjac_1761, retro_cjac_1820, retro_cjac_2261, retro_cjac_2389, retro_cjac_2390, retro_cjac_2391, retro_cjac_2445, retro_cjac_2523, retro_cjac_2659, retro_cjac_2663, retro_cjac_2909, retro_cjac_4205, retro_cjac_570, retro_cjac_635, retro_cjac_662, retro_cjac_872, retro_cjac_937, retro_cjac_966, retro_cjac_980,
Erinaceus europaeus	ENSEEUG00000006481	3 retrocopies	retro_eeur_219, retro_eeur_285, retro_eeur_369,
Homo sapiens	ENSG00000167085	15 retrocopies	retro_hsap_1113, retro_hsap_1514, retro_hsap_161, retro_hsap_1640, retro_hsap_2170, retro_hsap_2692, retro_hsap_3534, retro_hsap_3750, retro_hsap_3868, retro_hsap_3869, retro_hsap_4186, retro_hsap_4888, retro_hsap_517, retro_hsap_617, retro_hsap_776,
Gorilla gorilla	ENSGGOG00000028002	12 retrocopies	retro_ggor_124, retro_ggor_1722, retro_ggor_1876, retro_ggor_238, retro_ggor_2387, retro_ggor_246, retro_ggor_2607, retro_ggor_3053, retro_ggor_476, retro_ggor_643, retro_ggor_741, retro_ggor_870,
Macropus eugenii	ENSMEUG00000005122	1 retrocopy	retro_meug_708,
Microcebus murinus	ENSMICG00000006966	9 retrocopies	retro_mmur_1097, retro_mmur_1297, retro_mmur_1374, retro_mmur_1426, retro_mmur_1483, retro_mmur_1537, retro_mmur_1626, retro_mmur_62, retro_mmur_881,
Myotis lucifugus	ENSMLUG00000008203	2 retrocopies	retro_mluc_116, retro_mluc_2190,
Macaca mulatta	ENSMMUG00000000156	13 retrocopies	retro_mmul_1096, retro_mmul_1119, retro_mmul_1165, retro_mmul_1425, retro_mmul_151, retro_mmul_1565, retro_mmul_2148, retro_mmul_2420, retro_mmul_426, retro_mmul_521, retro_mmul_834, retro_mmul_866, retro_mmul_933,
Monodelphis domestica	ENSMODG00000012210	1 retrocopy	retro_mdom_812,
Oryctolagus cuniculus	ENSOCUG00000007209	1 retrocopy	retro_ocun_579 ,
Otolemur garnettii	ENSOGAG00000027015	1 retrocopy	retro_ogar_968,
Ochotona princeps	ENSOPRG00000000868	2 retrocopies	retro_opri_180, retro_opri_734,
Procavia capensis	ENSPCAG00000008851	1 retrocopy	retro_pcap_74,
Pan troglodytes	ENSPTRG00000009376	14 retrocopies	retro_ptro_1025, retro_ptro_1110, retro_ptro_154, retro_ptro_1656, retro_ptro_1817, retro_ptro_2401, retro_ptro_2545, retro_ptro_2841, retro_ptro_2964, retro_ptro_3256, retro_ptro_386, retro_ptro_451, retro_ptro_542, retro_ptro_686,
Rattus norvegicus	ENSRNOG00000046799	18 retrocopies	retro_rnor_1058, retro_rnor_1416, retro_rnor_1540, retro_rnor_1542, retro_rnor_2398, retro_rnor_2399, retro_rnor_2610, retro_rnor_2653, retro_rnor_2815, retro_rnor_2826, retro_rnor_2848, retro_rnor_2855, retro_rnor_2909, retro_rnor_292, retro_rnor_2948, retro_rnor_2949, retro_rnor_543, retro_rnor_898,
Ictidomys tridecemlineatus	ENSSTOG00000019929	2 retrocopies	retro_itri_337, retro_itri_945,