RetrogeneDB ID: retro_cpor_225

Retrocopy location

• Organism: Guinea Pig (Cavia porcellus)
• Coordinates: scaffold_100:1871443..1872404(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: DNAJA1
• Ensembl ID: ENSCPOG00000000462
• Aliases: None
• Description: Chaperone protein DnaJ [Source:UniProtKB/TrEMBL;Acc:H0UU01]

Sequence

>retro_cpor_225
GAGAAGAGGGGATTATATGACAAAGGAGGACAAGCAATGAAGGAGGGTGGAGCAGGTGGCAGTCTTGAGTCCCTCGTGGA
GGTCTTTGGTATGTTTTCTGGAAGAGGAGAAAGGATGCAGAAAAACGTAGTACATCAGCTCTTGGTTGCCTTAGAGGGTT
TATAAATGATGCCACAAGGAAACTGGCTCTGCAAAGCAACGTGACTTGTGACACGTGTGAAGACCAAGGTGGTAAGAAAG
GAAGTGTGGAGTGCTGTCCCAAACGCCAAGGTGCTGGAATGCAAATAAGAGCTCGTCAGAAAGACCCGAAATGGTTCGCA
AACTCAGTCCATGTGACTGGAGTGCCGGGCCACAGGGAATGCATCAGCCCTAAGCGTAGACATAAAAGCTTCAACAGAAG
GAAGATAGTCAGGGGGAAGAAGATTGAAGAAGCTCATACTGGCAAAGGCATGGAAAATGGCAGGAGATAACACTGCATGA
CGAGGGAGACCAAGAACCAGGGATGGAGCCAGGAGATGTTATCACTGTGTCAGACCAGAAGGAGCAGGCTGCTTTTATCG
ATGAGGAGACCTTGCCCTGTGTACTGATACACAACTGGTTGAAGCACTGTGTGGCTTCCAAAAGCCCATATCCACTCTTG
ACAACTGAACCATAATCATCACATCTCATCCAGGTCAAATTGTCAAGCAAGGAGACATCAAGTGTGTGCTAAATGAAGCC
ATGCAATTTATTGTAGACCATATGAAAAACATTTTGTAAGCAGCAAATTTAAGGTAAACTTTCCTGAAAATGGCTTTCTT
TCTCCAAATAAACTTTCCCTGCTGGAAAAACTCCTTCCGTGAGGAAGGAAGAAGAGACTGATGAAATGGCTCAAGTAGAA
CTGATAGCCTTTTGTTCAAGTCAGGAAAGATGGCACCATCATAATGGAGAAGCCTATGAGAATGACGAACATCATCCCAG
A

Alignment

ORF - retro_cpor_225 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 67.55 %
• Parental protein coverage: 83.38 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 8

Retrocopy - Parental Gene Alignment:

Parental  KKRELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRGKNVVHQLSVTLEDL-YNGATRKLA
          .KR.LYDKGG.QA.KEGGAGG...S....F.M.F.G.G....ER..KNVVHQL.V.LE.L..N.ATRKLA
Retrocopy EKRGLYDKGG-QAMKEGGAGGSLESLVEVFGM-FSGRG----ERMQKNVVHQLLVALEGL<INDATRKLA

Parental  LQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIG-PGMVQ-QIQSVCMECQ-GHGERISPKDRCK
          LQ.NV.CD.CE..GGKKG.VECCP...G.GMQIR..Q...P.MV..Q.QS...EC..GH.E.ISPK.R.K
Retrocopy LQSNVTCDTCEDQGGKKGSVECCPKRQGAGMQIRARQKD<PEMVR<QTQSM*LECR<GHRECISPKRRHK

Parental  SCNGRKIVREKKILEVHIDKGMKDG-QKITFHGEGDQEPGLEPGDIIIVLDQKDHAV-FTRRGEDLFMCM
          S.N.RKIVR.KKI.E.H..KGM..G.Q.IT.H.EGDQEPG.EPGD.I.V.DQK..A..F.R.G.DL..C.
Retrocopy SFNRRKIVRGKKIEEAHTGKGMENG<QEITLHDEGDQEPGMEPGDVITVSDQKEQAA<FYR*G-DLALCT

Parental  DIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGM-PIYRRPYEKGRLIIEFKVNFPEN
          D.QLVEALCGFQKPISTLDN.TI.ITSHPGQIVK.GDIKCVLNE.M..IY.RPYEK......FKVNFPEN
Retrocopy DTQLVEALCGFQKPISTLDN*TIIITSHPGQIVKQGDIKCVLNEAM<AIYCRPYEKHFVSSKFKVNFPEN

Parental  GFLSPDKLSLLEKLLP-ERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHPR
          GFLSP.KLSLLEKLLP..RKE.EETDEM.QVEL..F...QER..H.NGEAYE.DEHHPR
Retrocopy GFLSPNKLSLLEKLLP<VRKE-EETDEMAQVELIAFCSSQERWHHHNGEAYENDEHHPR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	73.68 RPM
SRP017611_kidney	0.00 RPM	68.05 RPM
SRP017611_liver	0.00 RPM	126.62 RPM
SRP040447_lung	0.08 RPM	135.06 RPM
SRP040447_skeletal_muscle	0.00 RPM	46.66 RPM

ChIP-Seq

Cavia porcellus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cpor_225 retrocopy.

TSS

Cavia porcellus was not studied using FANTOM5 data.

Lab

retro_cpor_225 was not experimentally validated.

Homology

Retrocopy orthology:

Cavia porcellus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 140 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000007589	4 retrocopies	retro_amel_1509, retro_amel_455, retro_amel_756, retro_amel_946,
Bos taurus	ENSBTAG00000016265	6 retrocopies	retro_btau_1440, retro_btau_1599, retro_btau_1800, retro_btau_1826, retro_btau_574, retro_btau_828,
Canis familiaris	ENSCAFG00000001818	23 retrocopies	retro_cfam_1111, retro_cfam_1153, retro_cfam_1218, retro_cfam_1229, retro_cfam_1315, retro_cfam_1352, retro_cfam_1420, retro_cfam_1457, retro_cfam_1520, retro_cfam_1668, retro_cfam_1833, retro_cfam_1941, retro_cfam_1949, retro_cfam_1994, retro_cfam_2004, retro_cfam_2162, retro_cfam_352, retro_cfam_391, retro_cfam_419, retro_cfam_749, retro_cfam_751, retro_cfam_923, retro_cfam_993,
Choloepus hoffmanni	ENSCHOG00000000631	9 retrocopies	retro_chof_1760, retro_chof_186, retro_chof_2020, retro_chof_2541, retro_chof_2694, retro_chof_287, retro_chof_417, retro_chof_498, retro_chof_946,
Callithrix jacchus	ENSCJAG00000008022	10 retrocopies	retro_cjac_1645, retro_cjac_1777, retro_cjac_2015, retro_cjac_2120, retro_cjac_2730, retro_cjac_2731, retro_cjac_2763, retro_cjac_3037, retro_cjac_3762, retro_cjac_887,
Cavia porcellus	ENSCPOG00000000462	6 retrocopies	retro_cpor_1456, retro_cpor_225 , retro_cpor_386, retro_cpor_396, retro_cpor_561, retro_cpor_781,
Cavia porcellus	ENSCPOG00000006955	1 retrocopy	retro_cpor_1466,
Dasypus novemcinctus	ENSDNOG00000018342	3 retrocopies	retro_dnov_1139, retro_dnov_640, retro_dnov_884,
Homo sapiens	ENSG00000086061	4 retrocopies	retro_hsap_2331, retro_hsap_2569, retro_hsap_3647, retro_hsap_4889,
Gorilla gorilla	ENSGGOG00000007030	3 retrocopies	retro_ggor_1603, retro_ggor_2463, retro_ggor_418,
Myotis lucifugus	ENSMLUG00000016086	7 retrocopies	retro_mluc_1245, retro_mluc_1485, retro_mluc_1737, retro_mluc_1878, retro_mluc_2062, retro_mluc_2579, retro_mluc_576,
Monodelphis domestica	ENSMODG00000003384	7 retrocopies	retro_mdom_1140, retro_mdom_1253, retro_mdom_1451, retro_mdom_1627, retro_mdom_1824, retro_mdom_742, retro_mdom_874,
Mus musculus	ENSMUSG00000028410	3 retrocopies	retro_mmus_2561, retro_mmus_2982, retro_mmus_3507,
Procavia capensis	ENSPCAG00000012273	2 retrocopies	retro_pcap_184, retro_pcap_220,
Pongo abelii	ENSPPYG00000019141	4 retrocopies	retro_pabe_1892, retro_pabe_2111, retro_pabe_2559, retro_pabe_2994,
Pan troglodytes	ENSPTRG00000020852	4 retrocopies	retro_ptro_1499, retro_ptro_1705, retro_ptro_177, retro_ptro_2472,
Pteropus vampyrus	ENSPVAG00000011470	1 retrocopy	retro_pvam_672,
Rattus norvegicus	ENSRNOG00000007029	2 retrocopies	retro_rnor_2208, retro_rnor_608,
Sorex araneus	ENSSARG00000001373	5 retrocopies	retro_sara_280, retro_sara_312, retro_sara_671, retro_sara_741, retro_sara_748,
Sarcophilus harrisii	ENSSHAG00000012366	1 retrocopy	retro_shar_762,
Ictidomys tridecemlineatus	ENSSTOG00000005200	4 retrocopies	retro_itri_265, retro_itri_303, retro_itri_378, retro_itri_809,
Tupaia belangeri	ENSTBEG00000000596	23 retrocopies	retro_tbel_1281, retro_tbel_134, retro_tbel_1529, retro_tbel_1542, retro_tbel_2260, retro_tbel_2293, retro_tbel_2316, retro_tbel_2428, retro_tbel_2445, retro_tbel_2917, retro_tbel_2965, retro_tbel_2972, retro_tbel_329, retro_tbel_3345, retro_tbel_3353, retro_tbel_3692, retro_tbel_4014, retro_tbel_4223, retro_tbel_432, retro_tbel_591, retro_tbel_617, retro_tbel_634, retro_tbel_842,
Tarsius syrichta	ENSTSYG00000001329	4 retrocopies	retro_tsyr_110, retro_tsyr_1384, retro_tsyr_1921, retro_tsyr_57,
Tursiops truncatus	ENSTTRG00000007387	4 retrocopies	retro_ttru_1181, retro_ttru_1551, retro_ttru_567, retro_ttru_783,