RetrogeneDB ID: retro_btau_1420

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 5:45728878..45729327(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSBTAG00000015395
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: RPS2
• Ensembl ID: ENSBTAG00000009535
• Aliases: RPS2, RPS2E
• Description: 40S ribosomal protein S2 [Source:UniProtKB/Swiss-Prot;Acc:O18789]

Sequence

>retro_btau_1420
TCTAAGGAAGTAGCCACTACCATCTGTGGGGCCATCATCCTGGCCAAGCTGTCCATTGTCCTCGTGCGAAGAGGCTACTG
GGGGAACAAGATCGGCAAGACCCACACAGTTCCTTGCAAGGTGACTAGCTGCTGTGGCTCCGTGCTGGTGCTCTTCATCC
CTGCCCCCAGAGGCACTGGCATCGTGTCCGCCCCTGTGCCCAAGAAGCTGCTGATGACGGCCGCCATCGATGACTGCTAC
ACTTTTGCCAGGGGCTGCACTGCCACCCTCGCAACTTCGCCAAGGCCACTTTTGATGCCATTTTCAAGACCTACAGTTAC
CTCACCCCTGACCTCTGGAAAGAGACAGTGTTCACCAAGTCTCCATATCAGGAATTCACTGACCATCTTGTGAAGACCCA
CACCAGTGTCTCCATGCAGAGGACCCAGGCCCCAGATGTAGCCACCACA

Alignment

ORF - retro_btau_1420 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.74 %
• Parental protein coverage: 51.19 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  SKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKL
          SKEVAT.I.GAIILAKLSIV.VRRGYWGNKIGK.HTVPCKVT..CGSVLV..IPAPRGTGIVSAPVPKKL
Retrocopy SKEVATTICGAIILAKLSIVLVRRGYWGNKIGKTHTVPCKVTSCCGSVLVLFIPAPRGTGIVSAPVPKKL

Parental  LMMAGIDDCYTSARGCTATLG-NFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTRVSV
          LM.A.IDDCYT.ARGCTATL..NFAKATFDAI.KTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHT.VS.
Retrocopy LMTAAIDDCYTFARGCTATLA<NFAKATFDAIFKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHTSVSM

Parental  QRTQAPAVATT
          QRTQAP.VATT
Retrocopy QRTQAPDVATT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.00 RPM	219.82 RPM
ERP005899_muscle	0.11 RPM	2816.03 RPM
SRP017611_brain	0.05 RPM	311.85 RPM
SRP017611_kidney	0.12 RPM	854.10 RPM
SRP017611_liver	0.00 RPM	655.49 RPM
SRP030211_testis	0.01 RPM	501.90 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1420 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1420 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1420 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 100 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000002549	1 retrocopy	retro_acar_57,
Bos taurus	ENSBTAG00000009535	7 retrocopies	retro_btau_1236, retro_btau_1420 , retro_btau_1656, retro_btau_317, retro_btau_590, retro_btau_661, retro_btau_956,
Canis familiaris	ENSCAFG00000019472	19 retrocopies	retro_cfam_1028, retro_cfam_1252, retro_cfam_1321, retro_cfam_1460, retro_cfam_1560, retro_cfam_1592, retro_cfam_1842, retro_cfam_1848, retro_cfam_1932, retro_cfam_1983, retro_cfam_2007, retro_cfam_2012, retro_cfam_2046, retro_cfam_2053, retro_cfam_2110, retro_cfam_271, retro_cfam_323, retro_cfam_490, retro_cfam_629,
Cavia porcellus	ENSCPOG00000011651	11 retrocopies	retro_cpor_1030, retro_cpor_1238, retro_cpor_1376, retro_cpor_1469, retro_cpor_1527, retro_cpor_177, retro_cpor_19, retro_cpor_437, retro_cpor_718, retro_cpor_769, retro_cpor_808,
Loxodonta africana	ENSLAFG00000004696	11 retrocopies	retro_lafr_1072, retro_lafr_1092, retro_lafr_1103, retro_lafr_174, retro_lafr_284, retro_lafr_327, retro_lafr_376, retro_lafr_75, retro_lafr_801, retro_lafr_812, retro_lafr_917,
Myotis lucifugus	ENSMLUG00000011660	1 retrocopy	retro_mluc_76,
Monodelphis domestica	ENSMODG00000016077	1 retrocopy	retro_mdom_536,
Mustela putorius furo	ENSMPUG00000015547	11 retrocopies	retro_mputfur_1100, retro_mputfur_1209, retro_mputfur_1212, retro_mputfur_1214, retro_mputfur_1391, retro_mputfur_1497, retro_mputfur_1566, retro_mputfur_369, retro_mputfur_540, retro_mputfur_624, retro_mputfur_931,
Mus musculus	ENSMUSG00000044533	1 retrocopy	retro_mmus_148,
Procavia capensis	ENSPCAG00000002090	2 retrocopies	retro_pcap_251, retro_pcap_433,
Rattus norvegicus	ENSRNOG00000014179	12 retrocopies	retro_rnor_1882, retro_rnor_2191, retro_rnor_2257, retro_rnor_2274, retro_rnor_2903, retro_rnor_438, retro_rnor_631, retro_rnor_681, retro_rnor_690, retro_rnor_809, retro_rnor_810, retro_rnor_878,
Sarcophilus harrisii	ENSSHAG00000015213	5 retrocopies	retro_shar_186, retro_shar_288, retro_shar_456, retro_shar_525, retro_shar_783,
Tursiops truncatus	ENSTTRG00000011393	12 retrocopies	retro_ttru_1341, retro_ttru_1346, retro_ttru_1414, retro_ttru_149, retro_ttru_1762, retro_ttru_1816, retro_ttru_37, retro_ttru_375, retro_ttru_419, retro_ttru_650, retro_ttru_719, retro_ttru_872,
Vicugna pacos	ENSVPAG00000006867	6 retrocopies	retro_vpac_114, retro_vpac_164, retro_vpac_220, retro_vpac_354, retro_vpac_379, retro_vpac_518,