RetrogeneDB ID: retro_mdom_69

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 4:416244677..416245304(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMODG00000018250
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: HMGB2
• Ensembl ID: ENSMODG00000003527
• Aliases: None
• Description: high mobility group box 2 [Source:HGNC Symbol;Acc:5000]

Sequence

>retro_mdom_69
ATGGGCAAGGTTCATATTAAGCCCAAAGTGAATCTGTCTTCATATGTCCACTTTTTATTAAACTGCAGGAACAAGCACAA
GGAACAACAGCCAAATGCTTACATCAATTTCAAAGAGTTCTCCAAAAAGTGCTCAGAAAAGTGGAAGACAATCTCTAAGC
ATGAAAAGTCCAAGTATGAAGCTATAGCCAAACTTGACAAAGCACGCTACCAGAAAGAAATGAAAAACTATGTTCCCCCT
GCAGGAATGAAGAGGAAGAAAAGAAGGAAGAAGGACCCCAAAGCTCCCAAGAGACCACCCTCATCTTTTATACTCTTCAG
TAGAGAGAATTATACAAAAATCAAGGGTGACAATCCACACTGGTCTGTAATAGAAGTGGCAAAATTCCTGGGGGAGATGT
GGTCCAAAAAGTCAGAGCAGGAGAAGCAACCTTATGAAGAGAAGGCAGCTAGACTGAGAACCAAGTACCACCAAGAACTC
ACAGCCTACCGAGTCAATTATGGTCAGGGATGTTCAAGAAAGAAAGGACCAGGGCCTTCTGGCCAGTATCAGAACAGAAA
GAAATCCAAGTCAGACAAGAAGTGTGAAAAATATGATGAATCTGATTCAGAAGGGGAGCTGGATTAG

Alignment

ORF - retro_mdom_69 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 52.22 %
• Parental protein coverage: 95.17 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KPRGKMSSYAFFVQTCREEHKKKHPDSPVNFAEFSKKCSERWKTMSAKEKSKFEDLAKGDKARYDREMKN
          KP....SSY..F...CR..HK...P....NF.EFSKKCSE.WKT.S..EKSK.E..AK.DKARY..EMKN
Retrocopy KPKVNLSSYVHFLLNCRNKHKEQQPNAYINFKEFSKKCSEKWKTISKHEKSKYEAIAKLDKARYQKEMKN

Parental  YVPPKG--DKKGKKKDPNAPKRPPSAFFLFCAEHRPKIKSEHPGLSIGDTAKKLGELWSEQSAKDKLPYE
          YVPP.G...KK..KKDP.APKRPPS.F.LF..E...KIK...P..S....AK.LGE.WS..S...K.PYE
Retrocopy YVPPAGMKRKKRRKKDPKAPKRPPSSFILFSRENYTKIKGDNPHWSVIEVAKFLGEMWSKKSEQEKQPYE

Parental  QKVAKLKEKYEKDIAAYRAK-GKGDAGKKGPGRPTG---SKKKNEPDEEEEDEDEEDEDEEDD
          .K.A.L..KY.....AYR...G.G...KKGPG.P.G.....KK...D...E..DE.D...E.D
Retrocopy EKAARLRTKYHQELTAYRVNYGQGCSRKKGPG-PSGQYQNRKKSKSDKKCEKYDESDSEGELD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	0.00 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_69 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_69 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 27 parental genes, and 112 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000015101	1 retrocopy	retro_btau_58,
Callithrix jacchus	ENSCJAG00000005112	2 retrocopies	retro_cjac_2555, retro_cjac_832,
Cavia porcellus	ENSCPOG00000003552	4 retrocopies	retro_cpor_1100, retro_cpor_604, retro_cpor_890, retro_cpor_980,
Dasypus novemcinctus	ENSDNOG00000019440	4 retrocopies	retro_dnov_1142, retro_dnov_1457, retro_dnov_454, retro_dnov_532,
Erinaceus europaeus	ENSEEUG00000012238	8 retrocopies	retro_eeur_118, retro_eeur_223, retro_eeur_345, retro_eeur_49, retro_eeur_54, retro_eeur_661, retro_eeur_702, retro_eeur_86,
Echinops telfairi	ENSETEG00000010379	3 retrocopies	retro_etel_1474, retro_etel_1841, retro_etel_2023,
Echinops telfairi	ENSETEG00000016379	1 retrocopy	retro_etel_414,
Felis catus	ENSFCAG00000004218	2 retrocopies	retro_fcat_279, retro_fcat_52,
Homo sapiens	ENSG00000164104	1 retrocopy	retro_hsap_3663,
Gorilla gorilla	ENSGGOG00000015882	1 retrocopy	retro_ggor_2474,
Loxodonta africana	ENSLAFG00000010417	3 retrocopies	retro_lafr_1096, retro_lafr_1142, retro_lafr_595,
Macropus eugenii	ENSMEUG00000002256	3 retrocopies	retro_meug_1920, retro_meug_1989, retro_meug_550,
Myotis lucifugus	ENSMLUG00000026303	4 retrocopies	retro_mluc_1113, retro_mluc_1381, retro_mluc_1726, retro_mluc_2011,
Monodelphis domestica	ENSMODG00000003527	3 retrocopies	retro_mdom_1160, retro_mdom_1919, retro_mdom_69 ,
Monodelphis domestica	ENSMODG00000005735	7 retrocopies	retro_mdom_1257, retro_mdom_1508, retro_mdom_1883, retro_mdom_1952, retro_mdom_587, retro_mdom_698, retro_mdom_831,
Monodelphis domestica	ENSMODG00000009238	14 retrocopies	retro_mdom_1088, retro_mdom_1144, retro_mdom_1228, retro_mdom_1689, retro_mdom_1727, retro_mdom_1819, retro_mdom_2007, retro_mdom_2024, retro_mdom_3, retro_mdom_434, retro_mdom_548, retro_mdom_72, retro_mdom_760, retro_mdom_958,
Mustela putorius furo	ENSMPUG00000001919	9 retrocopies	retro_mputfur_1134, retro_mputfur_1167, retro_mputfur_1379, retro_mputfur_1475, retro_mputfur_1631, retro_mputfur_1633, retro_mputfur_1644, retro_mputfur_940, retro_mputfur_989,
Mus musculus	ENSMUSG00000054717	23 retrocopies	retro_mmus_1477, retro_mmus_1745, retro_mmus_1974, retro_mmus_1975, retro_mmus_2269, retro_mmus_2527, retro_mmus_2528, retro_mmus_2529, retro_mmus_2530, retro_mmus_2531, retro_mmus_2843, retro_mmus_2884, retro_mmus_3248, retro_mmus_3426, retro_mmus_461, retro_mmus_626, retro_mmus_642, retro_mmus_796, retro_mmus_861, retro_mmus_901, retro_mmus_902, retro_mmus_904, retro_mmus_905,
Nomascus leucogenys	ENSNLEG00000006662	3 retrocopies	retro_nleu_113, retro_nleu_517, retro_nleu_550,
Oryctolagus cuniculus	ENSOCUG00000000074	1 retrocopy	retro_ocun_1829,
Otolemur garnettii	ENSOGAG00000017149	3 retrocopies	retro_ogar_3117, retro_ogar_3323, retro_ogar_3336,
Pongo abelii	ENSPPYG00000015204	3 retrocopies	retro_pabe_297, retro_pabe_3005, retro_pabe_3380,
Pan troglodytes	ENSPTRG00000016597	3 retrocopies	retro_ptro_19, retro_ptro_2484, retro_ptro_2789,
Pteropus vampyrus	ENSPVAG00000014656	1 retrocopy	retro_pvam_872,
Rattus norvegicus	ENSRNOG00000013167	2 retrocopies	retro_rnor_173, retro_rnor_54,
Ictidomys tridecemlineatus	ENSSTOG00000023980	2 retrocopies	retro_itri_1720, retro_itri_880,
Tursiops truncatus	ENSTTRG00000015650	1 retrocopy	retro_ttru_1640,