RetrogeneDB ID: retro_mmus_2232

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 3:27308405..27308675(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Arl5a
• Ensembl ID: ENSMUSG00000036093
• Aliases: Arl5a, 2410015N24Rik, 2810410P22Rik, AA408731, AW610751, Arl5, T25534
• Description: ADP-ribosylation factor-like 5A [Source:MGI Symbol;Acc:MGI:1922673]

Sequence

>retro_mmus_2232
GGTGGCCAAGAATCTCTTCTTTCTTCCGAGAATACTCCATATACTAACACAGAGTTTGTACCCGTTGCTGATGGTACAGA
AAGGGATTTCTGTAATAGAGATGAGCTCTACAAAATTTGAGCCCACAAGGACATAATGGAAACGGGATTACTGGCACATG
CTAATAAACAAGATGTGAAAGAATGTGTGACAGTGGCAGAAAAATCCCAATTTTTTAAAACAACTTCTATTGAAGATCGC
CAGTGGTATATCCAAGCATGTTGTATTCTT

Alignment

ORF - retro_mmus_2232 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 64.52 %
• Parental protein coverage: 51.96 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  GGQESLRPSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQDVKECMTVAE
          GGQESL..S.NT.YTNTEFV..V.D.T.R......R.ELYK..AH.D....GLL..ANKQDVKEC.TVAE
Retrocopy GGQESLLSSENTPYTNTEFV-PVADGTERDFCN--RDELYKI*AHKDIMETGLLAHANKQDVKECVTVAE

Parental  ISQFLKLTSIKDHQWHIQACCAL
          .SQF.K.TSI.D.QW.IQACC.L
Retrocopy KSQFFKTTSIEDRQWYIQACCIL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	61.44 RPM
SRP007412_cerebellum	0.00 RPM	57.97 RPM
SRP007412_heart	0.00 RPM	27.11 RPM
SRP007412_kidney	0.02 RPM	47.95 RPM
SRP007412_liver	0.00 RPM	72.80 RPM
SRP007412_testis	0.00 RPM	3.20 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_2232 was not detected

EST

No EST(s) were mapped for retro_mmus_2232 retrocopy.

TSS

No TSS is located nearby retro_mmus_2232 retrocopy 5' end.

Lab

retro_mmus_2232 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_2232 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 24 parental genes, and 118 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000005062	25 retrocopies	retro_chof_1109, retro_chof_1132, retro_chof_1205, retro_chof_1218, retro_chof_1407, retro_chof_1414, retro_chof_1443, retro_chof_1573, retro_chof_1712, retro_chof_1953, retro_chof_206, retro_chof_2081, retro_chof_2131, retro_chof_2142, retro_chof_2433, retro_chof_2464, retro_chof_2470, retro_chof_2713, retro_chof_373, retro_chof_547, retro_chof_836, retro_chof_857, retro_chof_865, retro_chof_972, retro_chof_98,
Callithrix jacchus	ENSCJAG00000003311	9 retrocopies	retro_cjac_1054, retro_cjac_1111, retro_cjac_1255, retro_cjac_1921, retro_cjac_2949, retro_cjac_3920, retro_cjac_4131, retro_cjac_4175, retro_cjac_4211,
Cavia porcellus	ENSCPOG00000005209	1 retrocopy	retro_cpor_913,
Dasypus novemcinctus	ENSDNOG00000013331	16 retrocopies	retro_dnov_105, retro_dnov_1165, retro_dnov_1244, retro_dnov_1953, retro_dnov_2159, retro_dnov_226, retro_dnov_2265, retro_dnov_2268, retro_dnov_2344, retro_dnov_2394, retro_dnov_563, retro_dnov_671, retro_dnov_713, retro_dnov_811, retro_dnov_818, retro_dnov_881,
Equus caballus	ENSECAG00000023672	1 retrocopy	retro_ecab_1087,
Erinaceus europaeus	ENSEEUG00000009350	3 retrocopies	retro_eeur_240, retro_eeur_642, retro_eeur_699,
Felis catus	ENSFCAG00000014742	2 retrocopies	retro_fcat_569, retro_fcat_65,
Homo sapiens	ENSG00000162980	5 retrocopies	retro_hsap_2549, retro_hsap_4715, retro_hsap_4768, retro_hsap_4894, retro_hsap_721,
Gorilla gorilla	ENSGGOG00000002066	5 retrocopies	retro_ggor_1131, retro_ggor_1594, retro_ggor_2930, retro_ggor_2971, retro_ggor_3056,
Loxodonta africana	ENSLAFG00000032104	4 retrocopies	retro_lafr_1178, retro_lafr_1228, retro_lafr_1244, retro_lafr_599,
Microcebus murinus	ENSMICG00000015788	7 retrocopies	retro_mmur_1271, retro_mmur_1487, retro_mmur_1586, retro_mmur_1618, retro_mmur_468, retro_mmur_652, retro_mmur_923,
Macaca mulatta	ENSMMUG00000010521	5 retrocopies	retro_mmul_2519, retro_mmul_2543, retro_mmul_2630, retro_mmul_616, retro_mmul_641,
Monodelphis domestica	ENSMODG00000003978	1 retrocopy	retro_mdom_75,
Mustela putorius furo	ENSMPUG00000000396	2 retrocopies	retro_mputfur_1477, retro_mputfur_352,
Mus musculus	ENSMUSG00000036093	1 retrocopy	retro_mmus_2232 ,
Mus musculus	ENSMUSG00000060904	1 retrocopy	retro_mmus_3285,
Nomascus leucogenys	ENSNLEG00000011191	2 retrocopies	retro_nleu_1259, retro_nleu_2280,
Otolemur garnettii	ENSOGAG00000011424	6 retrocopies	retro_ogar_1879, retro_ogar_2112, retro_ogar_2675, retro_ogar_3146, retro_ogar_3465, retro_ogar_728,
Pongo abelii	ENSPPYG00000012848	4 retrocopies	retro_pabe_3711, retro_pabe_3806, retro_pabe_3832, retro_pabe_621,
Pan troglodytes	ENSPTRG00000012538	5 retrocopies	retro_ptro_1486, retro_ptro_3134, retro_ptro_3175, retro_ptro_3262, retro_ptro_514,
Ictidomys tridecemlineatus	ENSSTOG00000016326	1 retrocopy	retro_itri_62,
Tupaia belangeri	ENSTBEG00000011511	8 retrocopies	retro_tbel_1173, retro_tbel_1540, retro_tbel_3202, retro_tbel_3464, retro_tbel_3681, retro_tbel_3835, retro_tbel_4207, retro_tbel_4665,
Tursiops truncatus	ENSTTRG00000015564	2 retrocopies	retro_ttru_1008, retro_ttru_1843,
Vicugna pacos	ENSVPAG00000002172	2 retrocopies	retro_vpac_318, retro_vpac_399,