RetrogeneDB ID: retro_cfam_437

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 11:73019889..73020425(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCAFG00000003544
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: RPL12
• Ensembl ID: ENSCAFG00000020136
• Aliases: None
• Description: 60S ribosomal protein L12 [Source:UniProtKB/Swiss-Prot;Acc:E2RR58]

Sequence

>retro_cfam_437
CTTTGGTCGTCCTGAATCCGGGTTCATCCAACACCAGCTGCCTCCACCATGCCGCCTAAGTTTGACCCCAACGAGATCAA
AGTCGTGTACCTGAGGTGCACCAGTGGTGAGGTCGGTGCCATGTCTGCCCTGGCCCCGAAGATCGGTCCGCTGGGTCTGT
CTCCAAAAAAGGTTGGTGATGACATCGCCAAGGCAACTGGTGATTGGAAGGGTCTAAGGATTACAGTGAAACTGACCATT
CAGAGCAGACAGGCCCAGATTGAAGTGGTACCTTCTGCCTTTGCCCTGATTATCAAAGCCCTCAAGGAACATCAAGAGAC
AGAAAGAAGCAGAAAAACATTGAGCACAGTGGAAATATCACTTTTGATGAGATTGTCAATATTGACAGACAGATGCGACA
CCGATCTTTAGCCAGAGAACTCTCTGGAACCATTAAAGAAATCCTGGGGACTGCCCAGTCTGTGGGCTGCAATGTTGATG
GCCATCACCCTCATGACATCATAGATGACATCAATAGTGGTGCAGTGGAATGTCCA

Alignment

ORF - retro_cfam_437 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 92.78 %
• Parental protein coverage: 94.21 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  LRSSRIRVHPTPAASAMPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWK
          L.SS.IRVHPTPAAS.MPPKFDPNEIKVVYLRCT.GEVGA.SALAPKIGPLGLSPKKVGDDIAKATGDWK
Retrocopy LWSS*IRVHPTPAASTMPPKFDPNEIKVVYLRCTSGEVGAMSALAPKIGPLGLSPKKVGDDIAKATGDWK

Parental  GLRITVKLTIQNRQAQIEVVPSASALIIKALKE-PPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLAR
          GLRITVKLTIQ.RQAQIEVVPSA.ALIIKALKE...RDRKKQKNI.HSGNITFDEIVNI.RQMRHRSLAR
Retrocopy GLRITVKLTIQSRQAQIEVVPSAFALIIKALKE<TSRDRKKQKNIEHSGNITFDEIVNIDRQMRHRSLAR

Parental  ELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECP
          ELSGTIKEILGTAQSVGCNVDG.HPHDIIDDINSGAVECP
Retrocopy ELSGTIKEILGTAQSVGCNVDGHHPHDIIDDINSGAVECP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.08 RPM	305.54 RPM
SRP017611_brain	0.08 RPM	91.54 RPM
SRP017611_kidney	0.26 RPM	791.32 RPM
SRP017611_liver	0.07 RPM	227.18 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_437 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_437 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_437 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 319 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016712	15 retrocopies	retro_amel_1131, retro_amel_1172, retro_amel_1208, retro_amel_1400, retro_amel_1508, retro_amel_1558, retro_amel_17, retro_amel_174, retro_amel_1856, retro_amel_203, retro_amel_260, retro_amel_293, retro_amel_688, retro_amel_876, retro_amel_952,
Canis familiaris	ENSCAFG00000020136	31 retrocopies	retro_cfam_1016, retro_cfam_1139, retro_cfam_1141, retro_cfam_1143, retro_cfam_1151, retro_cfam_1166, retro_cfam_1181, retro_cfam_1203, retro_cfam_1257, retro_cfam_1470, retro_cfam_1484, retro_cfam_1558, retro_cfam_1591, retro_cfam_1597, retro_cfam_1632, retro_cfam_1796, retro_cfam_1880, retro_cfam_1986, retro_cfam_2009, retro_cfam_2094, retro_cfam_2194, retro_cfam_437 , retro_cfam_588, retro_cfam_706, retro_cfam_728, retro_cfam_748, retro_cfam_759, retro_cfam_76, retro_cfam_850, retro_cfam_950, retro_cfam_955,
Cavia porcellus	ENSCPOG00000013769	18 retrocopies	retro_cpor_1, retro_cpor_1069, retro_cpor_1108, retro_cpor_1373, retro_cpor_140, retro_cpor_1473, retro_cpor_1510, retro_cpor_1513, retro_cpor_1514, retro_cpor_313, retro_cpor_342, retro_cpor_553, retro_cpor_556, retro_cpor_664, retro_cpor_874, retro_cpor_910, retro_cpor_921, retro_cpor_954,
Equus caballus	ENSECAG00000010622	17 retrocopies	retro_ecab_1024, retro_ecab_1027, retro_ecab_1119, retro_ecab_157, retro_ecab_335, retro_ecab_379, retro_ecab_457, retro_ecab_475, retro_ecab_605, retro_ecab_666, retro_ecab_679, retro_ecab_699, retro_ecab_708, retro_ecab_843, retro_ecab_895, retro_ecab_967, retro_ecab_973,
Echinops telfairi	ENSETEG00000006941	7 retrocopies	retro_etel_1508, retro_etel_1714, retro_etel_318, retro_etel_345, retro_etel_750, retro_etel_919, retro_etel_983,
Felis catus	ENSFCAG00000010302	31 retrocopies	retro_fcat_1078, retro_fcat_1115, retro_fcat_1118, retro_fcat_1149, retro_fcat_1206, retro_fcat_1276, retro_fcat_1288, retro_fcat_1298, retro_fcat_1376, retro_fcat_1482, retro_fcat_1527, retro_fcat_1637, retro_fcat_1638, retro_fcat_1676, retro_fcat_1854, retro_fcat_1873, retro_fcat_1977, retro_fcat_2009, retro_fcat_302, retro_fcat_35, retro_fcat_352, retro_fcat_359, retro_fcat_415, retro_fcat_455, retro_fcat_502, retro_fcat_509, retro_fcat_53, retro_fcat_638, retro_fcat_767, retro_fcat_819, retro_fcat_902,
Latimeria chalumnae	ENSLACG00000015373	3 retrocopies	retro_lcha_31, retro_lcha_87, retro_lcha_92,
Macropus eugenii	ENSMEUG00000007380	12 retrocopies	retro_meug_1102, retro_meug_1107, retro_meug_1199, retro_meug_1357, retro_meug_1426, retro_meug_1611, retro_meug_1634, retro_meug_1691, retro_meug_1953, retro_meug_265, retro_meug_479, retro_meug_493,
Myotis lucifugus	ENSMLUG00000009551	2 retrocopies	retro_mluc_1222, retro_mluc_1797,
Myotis lucifugus	ENSMLUG00000013404	1 retrocopy	retro_mluc_14,
Monodelphis domestica	ENSMODG00000004571	9 retrocopies	retro_mdom_1061, retro_mdom_1177, retro_mdom_1192, retro_mdom_1526, retro_mdom_1719, retro_mdom_1871, retro_mdom_1947, retro_mdom_309, retro_mdom_925,
Mustela putorius furo	ENSMPUG00000013832	34 retrocopies	retro_mputfur_1102, retro_mputfur_1104, retro_mputfur_1137, retro_mputfur_1192, retro_mputfur_1223, retro_mputfur_1283, retro_mputfur_1329, retro_mputfur_1467, retro_mputfur_1526, retro_mputfur_1580, retro_mputfur_260, retro_mputfur_331, retro_mputfur_363, retro_mputfur_445, retro_mputfur_489, retro_mputfur_500, retro_mputfur_508, retro_mputfur_521, retro_mputfur_533, retro_mputfur_534, retro_mputfur_544, retro_mputfur_559, retro_mputfur_594, retro_mputfur_61, retro_mputfur_622, retro_mputfur_632, retro_mputfur_651, retro_mputfur_824, retro_mputfur_828, retro_mputfur_843, retro_mputfur_868, retro_mputfur_884, retro_mputfur_913, retro_mputfur_977,
Otolemur garnettii	ENSOGAG00000000597	120 retrocopies	retro_ogar_1002, retro_ogar_1010, retro_ogar_1049, retro_ogar_1069, retro_ogar_1106, retro_ogar_1117, retro_ogar_1137, retro_ogar_1140, retro_ogar_1181, retro_ogar_1188, retro_ogar_1189, retro_ogar_1192, retro_ogar_1230, retro_ogar_1247, retro_ogar_1263, retro_ogar_1295, retro_ogar_1331, retro_ogar_1341, retro_ogar_1408, retro_ogar_1409, retro_ogar_1427, retro_ogar_1457, retro_ogar_1464, retro_ogar_1489, retro_ogar_1503, retro_ogar_1534, retro_ogar_1536, retro_ogar_1550, retro_ogar_1569, retro_ogar_1570, retro_ogar_1579, retro_ogar_1606, retro_ogar_1621, retro_ogar_1709, retro_ogar_1717, retro_ogar_1739, retro_ogar_1789, retro_ogar_1803, retro_ogar_1810, retro_ogar_1825, retro_ogar_1836, retro_ogar_1881, retro_ogar_1885, retro_ogar_1916, retro_ogar_1923, retro_ogar_1937, retro_ogar_1941, retro_ogar_1948, retro_ogar_1969, retro_ogar_1975, retro_ogar_1987, retro_ogar_2055, retro_ogar_2115, retro_ogar_2134, retro_ogar_2172, retro_ogar_2179, retro_ogar_2180, retro_ogar_2208, retro_ogar_2209, retro_ogar_2230, retro_ogar_2291, retro_ogar_2323, retro_ogar_2387, retro_ogar_2483, retro_ogar_2495, retro_ogar_2511, retro_ogar_2570, retro_ogar_2620, retro_ogar_2622, retro_ogar_2624, retro_ogar_2749, retro_ogar_2768, retro_ogar_2809, retro_ogar_2904, retro_ogar_2935, retro_ogar_2945, retro_ogar_2953, retro_ogar_2980, retro_ogar_3004, retro_ogar_3017, retro_ogar_303, retro_ogar_3035, retro_ogar_3128, retro_ogar_3135, retro_ogar_3164, retro_ogar_3394, retro_ogar_3489, retro_ogar_395, retro_ogar_398, retro_ogar_412, retro_ogar_427, retro_ogar_452, retro_ogar_480, retro_ogar_512, retro_ogar_513, retro_ogar_538, retro_ogar_560, retro_ogar_587, retro_ogar_624, retro_ogar_636, retro_ogar_653, retro_ogar_655, retro_ogar_667, retro_ogar_668, retro_ogar_669, retro_ogar_683, retro_ogar_700, retro_ogar_734, retro_ogar_737, retro_ogar_744, retro_ogar_747, retro_ogar_775, retro_ogar_818, retro_ogar_853, retro_ogar_868, retro_ogar_901, retro_ogar_927, retro_ogar_956, retro_ogar_962, retro_ogar_964,
Rattus norvegicus	ENSRNOG00000016220	4 retrocopies	retro_rnor_166, retro_rnor_236, retro_rnor_247, retro_rnor_312,
Sarcophilus harrisii	ENSSHAG00000017864	8 retrocopies	retro_shar_140, retro_shar_266, retro_shar_284, retro_shar_335, retro_shar_346, retro_shar_453, retro_shar_508, retro_shar_646,
Ictidomys tridecemlineatus	ENSSTOG00000027425	7 retrocopies	retro_itri_1128, retro_itri_1197, retro_itri_1498, retro_itri_445, retro_itri_790, retro_itri_833, retro_itri_840,