RetrogeneDB ID: retro_mmus_218

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 13:108670602..108671397(+)
• Located in intron of: ENSMUSG00000021699

Retrocopy information

• Ensembl ID: ENSMUSG00000059751
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: Rps3a1
• Ensembl ID: ENSMUSG00000028081
• Aliases: Rps3a1, Rps3a
• Description: ribosomal protein S3A1 [Source:MGI Symbol;Acc:MGI:1202063]

Sequence

>retro_mmus_218
ATGGCGGTCGGCAAGAACAAGCGCCTGACGAAAGGTGGCAAGAAGGGAGCTAAGAAGAAAGTGGTCGATCCATTTTCTAA
GAAAGACTGGTACGATGTGAAAGCTCCAGCCATGTTCAATATTAGGAACATCGGGAAGACACTAGTCACGAGGACTCAAG
GAACCAAAATTGCCTCTGATGGCCTCAAGGGTCGTGTGTTTGAAGTGAGCCTTGCCGATCTACAGAATGATGAAGTTGCG
TTTAGAAAATTCAAGCTAACCACTGAGGACGTTCAGGGCAAAAACTGTCTGACTAACTTCCATGGTATGGATCTTACCCG
GGACAAAATGTGCTCCATGGTCAAGAAGTGGCAGACCATGATTGAAGCTCACGTTGATGTCAAGACGACCGATGGGTATT
TGCTCCGACTTTTCTGTGTTGGCTTCTCTAAGAAACGCAACAACCAGATAAGAAAGACATCCTATGCGCAGCACCAGCAA
GTCCGCCAGATCCGGAAGAAGATGATGGAAATCATGACCCGAGAGGTGCAGACCAATGACTTGAAGGAAGTAGTTAATAA
ACTGATTCCAGACAGCATTGGTAAAGACATAGAAAAGGCTTGCCAGTCCATTTATCCTCTCCATGACGTCTTTGTTAGAA
AAGTAAAAATGCTGAAGAAGCCCAAGTTTGAATTGGGCAAGCTCATGGAGCTGCATGGGGAAGGCGGCAGCTCTGGCAAA
GCAGCTGGAGACGAGACGGGTGCTAAGGTTGAGCGAGCTGATGGATATGAACCGCCAGTCCAAGAATCAGTATAA

Alignment

ORF - retro_mmus_218 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 99.24 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVS
          MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVS
Retrocopy MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVS

Parental  LADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCV
          LADLQNDEVAFRKFKL.TEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCV
Retrocopy LADLQNDEVAFRKFKLTTEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCV

Parental  GFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDV
          GF.KKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDV
Retrocopy GFSKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKACQSIYPLHDV

Parental  FVRKVKMLKKPKFELGKLMELHGEGGSSGKAAGDETGAKVERADGYEPPVQESV
          FVRKVKMLKKPKFELGKLMELHGEGGSSGKAAGDETGAKVERADGYEPPVQESV
Retrocopy FVRKVKMLKKPKFELGKLMELHGEGGSSGKAAGDETGAKVERADGYEPPVQESV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	4.56 RPM	87.75 RPM
SRP007412_cerebellum	12.77 RPM	33.22 RPM
SRP007412_heart	0.22 RPM	106.53 RPM
SRP007412_kidney	15.78 RPM	81.85 RPM
SRP007412_liver	9.07 RPM	82.55 RPM
SRP007412_testis	8.14 RPM	17.98 RPM

ChIP-Seq

RNA Polymerase II actvity near the 5' end of retro_mmus_218 was not detected

EST

No EST(s) were mapped for retro_mmus_218 retrocopy.

TSS

TSS No.	TSS Name	TSS expression level (Expr) in TPM range:
		no expression	0 < Expr ≤ 1	1 < Expr ≤ 5	5 < Expr ≤ 10	Expr > 10
TSS #1	TSS_26490	76 libraries	251 libraries	113 libraries	62 libraries	570 libraries

The graphical summary, for retro_mmus_218 TSS expression levels > 0 TPM .
TSS expression levels were studied across 1072 TSS-CAGE libraries, based on FANTOM5 data.
The expression values were visualized using beanplot. If you have any doubts, how to read it, read more in Kampstra P (2008)

Lab

retro_mmus_218 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_218 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 32 parental genes, and 397 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000018425	11 retrocopies	retro_amel_1333, retro_amel_1361, retro_amel_1380, retro_amel_1514, retro_amel_159, retro_amel_1697, retro_amel_1732, retro_amel_1739, retro_amel_230, retro_amel_367, retro_amel_863,
Bos taurus	ENSBTAG00000009908	3 retrocopies	retro_btau_1284, retro_btau_1733, retro_btau_233,
Canis familiaris	ENSCAFG00000007990	7 retrocopies	retro_cfam_103, retro_cfam_146, retro_cfam_169, retro_cfam_170, retro_cfam_179, retro_cfam_222, retro_cfam_77,
Choloepus hoffmanni	ENSCHOG00000007238	34 retrocopies	retro_chof_1076, retro_chof_1092, retro_chof_1207, retro_chof_126, retro_chof_1309, retro_chof_1311, retro_chof_1341, retro_chof_1362, retro_chof_1377, retro_chof_1393, retro_chof_1395, retro_chof_1441, retro_chof_1488, retro_chof_1490, retro_chof_1598, retro_chof_1626, retro_chof_2056, retro_chof_2179, retro_chof_220, retro_chof_2201, retro_chof_2282, retro_chof_2417, retro_chof_2465, retro_chof_2500, retro_chof_2613, retro_chof_2628, retro_chof_2635, retro_chof_2668, retro_chof_342, retro_chof_370, retro_chof_685, retro_chof_824, retro_chof_826, retro_chof_912,
Callithrix jacchus	ENSCJAG00000002268	7 retrocopies	retro_cjac_2, retro_cjac_21, retro_cjac_249, retro_cjac_312, retro_cjac_337, retro_cjac_368, retro_cjac_78,
Cavia porcellus	ENSCPOG00000015569	9 retrocopies	retro_cpor_1154, retro_cpor_1229, retro_cpor_210, retro_cpor_383, retro_cpor_460, retro_cpor_555, retro_cpor_609, retro_cpor_646, retro_cpor_789,
Dipodomys ordii	ENSDORG00000002250	10 retrocopies	retro_dord_142, retro_dord_168, retro_dord_193, retro_dord_209, retro_dord_229, retro_dord_314, retro_dord_380, retro_dord_752, retro_dord_757, retro_dord_95,
Equus caballus	ENSECAG00000009573	6 retrocopies	retro_ecab_168, retro_ecab_222, retro_ecab_256, retro_ecab_597, retro_ecab_626, retro_ecab_885,
Erinaceus europaeus	ENSEEUG00000004994	4 retrocopies	retro_eeur_297, retro_eeur_510, retro_eeur_517, retro_eeur_66,
Felis catus	ENSFCAG00000031288	5 retrocopies	retro_fcat_1110, retro_fcat_134, retro_fcat_1878, retro_fcat_780, retro_fcat_858,
Homo sapiens	ENSG00000145425	40 retrocopies	retro_hsap_1080, retro_hsap_1178, retro_hsap_1320, retro_hsap_144, retro_hsap_1507, retro_hsap_1559, retro_hsap_1620, retro_hsap_1891, retro_hsap_1994, retro_hsap_2575, retro_hsap_2578, retro_hsap_2607, retro_hsap_2700, retro_hsap_274, retro_hsap_2803, retro_hsap_2908, retro_hsap_2909, retro_hsap_3020, retro_hsap_3112, retro_hsap_313, retro_hsap_3213, retro_hsap_3366, retro_hsap_3675, retro_hsap_3876, retro_hsap_3878, retro_hsap_3879, retro_hsap_3910, retro_hsap_3929, retro_hsap_3931, retro_hsap_4017, retro_hsap_4020, retro_hsap_4021, retro_hsap_588, retro_hsap_602, retro_hsap_613, retro_hsap_683, retro_hsap_789, retro_hsap_838, retro_hsap_888, retro_hsap_914,
Gorilla gorilla	ENSGGOG00000003182	2 retrocopies	retro_ggor_70, retro_ggor_97,
Loxodonta africana	ENSLAFG00000017660	3 retrocopies	retro_lafr_10, retro_lafr_38, retro_lafr_385,
Microcebus murinus	ENSMICG00000004921	9 retrocopies	retro_mmur_1230, retro_mmur_1289, retro_mmur_193, retro_mmur_299, retro_mmur_330, retro_mmur_526, retro_mmur_592, retro_mmur_626, retro_mmur_945,
Myotis lucifugus	ENSMLUG00000014788	8 retrocopies	retro_mluc_1197, retro_mluc_1397, retro_mluc_1568, retro_mluc_1846, retro_mluc_2130, retro_mluc_2158, retro_mluc_2388, retro_mluc_862,
Macaca mulatta	ENSMMUG00000021821	1 retrocopy	retro_mmul_2297,
Monodelphis domestica	ENSMODG00000000969	6 retrocopies	retro_mdom_1040, retro_mdom_1229, retro_mdom_1396, retro_mdom_1480, retro_mdom_627, retro_mdom_694,
Mustela putorius furo	ENSMPUG00000007139	8 retrocopies	retro_mputfur_1293, retro_mputfur_1363, retro_mputfur_278, retro_mputfur_316, retro_mputfur_504, retro_mputfur_695, retro_mputfur_764, retro_mputfur_847,
Mus musculus	ENSMUSG00000028081	2 retrocopies	retro_mmus_218 , retro_mmus_254,
Nomascus leucogenys	ENSNLEG00000005815	26 retrocopies	retro_nleu_1160, retro_nleu_1177, retro_nleu_1402, retro_nleu_1472, retro_nleu_1483, retro_nleu_1487, retro_nleu_1816, retro_nleu_1878, retro_nleu_1992, retro_nleu_209, retro_nleu_2437, retro_nleu_2567, retro_nleu_2571, retro_nleu_2753, retro_nleu_281, retro_nleu_2979, retro_nleu_3087, retro_nleu_443, retro_nleu_526, retro_nleu_654, retro_nleu_658, retro_nleu_758, retro_nleu_767, retro_nleu_799, retro_nleu_942, retro_nleu_962,
Oryctolagus cuniculus	ENSOCUG00000007011	1 retrocopy	retro_ocun_257,
Procavia capensis	ENSPCAG00000015040	6 retrocopies	retro_pcap_211, retro_pcap_286, retro_pcap_355, retro_pcap_420, retro_pcap_456, retro_pcap_57,
Pongo abelii	ENSPPYG00000025869	27 retrocopies	retro_pabe_1339, retro_pabe_1572, retro_pabe_1636, retro_pabe_1895, retro_pabe_1899, retro_pabe_2117, retro_pabe_2570, retro_pabe_2578, retro_pabe_2661, retro_pabe_2769, retro_pabe_2779, retro_pabe_2826, retro_pabe_2942, retro_pabe_3014, retro_pabe_3076, retro_pabe_3186, retro_pabe_3214, retro_pabe_3560, retro_pabe_369, retro_pabe_3692, retro_pabe_394, retro_pabe_473, retro_pabe_550, retro_pabe_602, retro_pabe_789, retro_pabe_912, retro_pabe_985,
Pteropus vampyrus	ENSPVAG00000015406	24 retrocopies	retro_pvam_1053, retro_pvam_1056, retro_pvam_1058, retro_pvam_1138, retro_pvam_1180, retro_pvam_1203, retro_pvam_1476, retro_pvam_149, retro_pvam_311, retro_pvam_330, retro_pvam_354, retro_pvam_36, retro_pvam_368, retro_pvam_376, retro_pvam_462, retro_pvam_486, retro_pvam_582, retro_pvam_73, retro_pvam_754, retro_pvam_799, retro_pvam_86, retro_pvam_893, retro_pvam_917, retro_pvam_996,
Rattus norvegicus	ENSRNOG00000011893	1 retrocopy	retro_rnor_198,
Sorex araneus	ENSSARG00000000717	15 retrocopies	retro_sara_103, retro_sara_178, retro_sara_238, retro_sara_257, retro_sara_390, retro_sara_401, retro_sara_449, retro_sara_451, retro_sara_482, retro_sara_63, retro_sara_666, retro_sara_676, retro_sara_723, retro_sara_762, retro_sara_91,
Sarcophilus harrisii	ENSSHAG00000015088	2 retrocopies	retro_shar_777, retro_shar_95,
Sus scrofa	ENSSSCG00000009019	3 retrocopies	retro_sscr_27, retro_sscr_749, retro_sscr_762,
Ictidomys tridecemlineatus	ENSSTOG00000024203	1 retrocopy	retro_itri_58,
Tupaia belangeri	ENSTBEG00000002963	98 retrocopies	retro_tbel_1005, retro_tbel_11, retro_tbel_1119, retro_tbel_116, retro_tbel_1232, retro_tbel_1318, retro_tbel_133, retro_tbel_137, retro_tbel_1375, retro_tbel_1378, retro_tbel_1383, retro_tbel_1417, retro_tbel_1421, retro_tbel_1509, retro_tbel_1686, retro_tbel_1698, retro_tbel_172, retro_tbel_1720, retro_tbel_1721, retro_tbel_1744, retro_tbel_1814, retro_tbel_1829, retro_tbel_1856, retro_tbel_1896, retro_tbel_1948, retro_tbel_1960, retro_tbel_1999, retro_tbel_206, retro_tbel_2200, retro_tbel_2306, retro_tbel_2463, retro_tbel_2483, retro_tbel_2510, retro_tbel_2626, retro_tbel_2654, retro_tbel_2657, retro_tbel_2745, retro_tbel_2759, retro_tbel_2760, retro_tbel_2764, retro_tbel_281, retro_tbel_2857, retro_tbel_2957, retro_tbel_2959, retro_tbel_3114, retro_tbel_317, retro_tbel_3212, retro_tbel_3255, retro_tbel_3259, retro_tbel_3299, retro_tbel_336, retro_tbel_3372, retro_tbel_3416, retro_tbel_3471, retro_tbel_3486, retro_tbel_3513, retro_tbel_3558, retro_tbel_3613, retro_tbel_3631, retro_tbel_3655, retro_tbel_3705, retro_tbel_373, retro_tbel_375, retro_tbel_3755, retro_tbel_3786, retro_tbel_3815, retro_tbel_3823, retro_tbel_3832, retro_tbel_386, retro_tbel_3882, retro_tbel_39, retro_tbel_3947, retro_tbel_3966, retro_tbel_399, retro_tbel_4116, retro_tbel_4144, retro_tbel_4147, retro_tbel_4211, retro_tbel_4220, retro_tbel_423, retro_tbel_4294, retro_tbel_4304, retro_tbel_4347, retro_tbel_438, retro_tbel_4428, retro_tbel_445, retro_tbel_4579, retro_tbel_598, retro_tbel_619, retro_tbel_623, retro_tbel_671, retro_tbel_859, retro_tbel_90, retro_tbel_912, retro_tbel_92, retro_tbel_928, retro_tbel_956, retro_tbel_973,
Tursiops truncatus	ENSTTRG00000013094	10 retrocopies	retro_ttru_101, retro_ttru_1014, retro_ttru_1456, retro_ttru_170, retro_ttru_1789, retro_ttru_1945, retro_ttru_263, retro_ttru_319, retro_ttru_779, retro_ttru_940,
Vicugna pacos	ENSVPAG00000004235	8 retrocopies	retro_vpac_253, retro_vpac_31, retro_vpac_322, retro_vpac_439, retro_vpac_486, retro_vpac_497, retro_vpac_529, retro_vpac_88,